Chemically induced graft copolymerization of 2-hydroxyethyl methacrylate onto polyurethane surface for improving blood compatibility

He, Chunli; Wang, Miao; Cai, Xianmei; Huang, Xiaobo; Li, Li; Zhu, Hongmin; Shen, Jian; Yuan, Jiang

doi:10.1016/j.apsusc.2011.08.074

Cited by 81 publications

(45 citation statements)

References 25 publications

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“…The grafting of functional molecules to PU has previously been applied for improving biocompatibility [18,19], hydrophilicity [20], low-temperature flexibility [21], and antimicrobial activity [22]. However, the hydrophilicity of cellulose must be reduced for grafting to PU because of compatibility problems with the PU.…”

Section: Introductionmentioning

confidence: 99%

Polyurethane membrane functionalization with the grafted cellulose derivatives to control water vapor permeability

et al. 2015

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Cellulose derivatives were grafted to polyurethane (PU), and the effect of grafting on water vapor permeation was evaluated. The cellulose derivative grafting did not significantly change the soft segment melting temperature; however, the grafting affected the enthalpy change for the soft segment melting. The light cross-linking by the grafted cellulose derivatives significantly increased PU tensile strength but did not affect tensile strain. Unexpectedly, water vapor permeability (WVP) at 50 o C was decreased by the grafted cellulose derivative, and the decrease in WVP was particularly severe for the cellulose acetate-PU. The molecular weight and capping group of the cellulose derivative affected PU membrane WVP. In addition, the PU layer became less permeable to water vapor with the increase of cellulose derivative content because the water vapor path was restricted.

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Section: Introductionmentioning

confidence: 99%

Polyurethane membrane functionalization with the grafted cellulose derivatives to control water vapor permeability

et al. 2015

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“…Segmented polyurethanes have gained considerable scientific and technical interest as useful biomaterials for implants or biomedical devices [1][2][3][4]. This class of polymers have been extensively used for various commercial and experimental blood contacting and tissue-contacting application, because of their generally excellent surface physical properties, together with their fairly good biocompatibility and haemocompatibility characteristics [5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of polyurethane based on cellulose derivative-ketoprofen biosystem for implant biomedical devices

Macocinschi¹,

Filip²,

Vlad³

et al. 2013

International Journal of Biological Macromolecules

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“…Therefore, the development of biodegradable PU materials becomes the key to solving this problem. Currently available biodegradable PU include oligosaccharides-derived PU; lignin, tannin, and bark-derived PU; cellulose derivatives of PU; and starch derivatives of PU [44,47]. Since PU has good biological compatibility and resists thrombosis, biodegradable PU has great development potential in the biomedical field.…”

Section: Chemically Synthesized Polymer Materialsmentioning

confidence: 99%

“…Anti-adhesion materials, patch, drug-delivery carrier, bone-fixing device, suture, tissue-engineered scaffold [40][41][42] Biocompatibility, good mechanical properties, safe, non-toxic [40][41][42] Poor toughness, degradation speed slow, hydrophobicity, lack of reactive side chain groups [40][41][42] Polyurethane Excipients, medical bandage [43][44][45] Low cost, rich resource, good mechanical properties [43,44,46,47] Degradation speed slow [43,46,47] Poly(lactic-glycolic acid) (PLGA)…”

Section: Chitosanmentioning

confidence: 99%

Polymer-Based Nanomaterials and Applications for Vaccines and Drugs

et al. 2018

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Nanotechnology plays a significant role in drug development. As carriers, polymeric nanoparticles can deliver vaccine antigens, proteins, and drugs to the desired site of action. Polymeric nanoparticles with lower cytotoxicity can protect the delivered antigens or drugs from degradation under unfavorable conditions via a mucosal administration route; further, the uptake of nanoparticles by antigen-presenting cells can increase and induce potent immune responses. Additionally, nanomaterials are widely used in vaccine delivery systems because nanomaterials can make the vaccine antigen long-acting. This review focuses on some biodegradable polymer materials such as natural polymeric nanomaterials, chemically synthesized polymer materials, and biosynthesized polymeric materials, and points out the advantages and the direction of research on degradable polymeric materials. The application and future perspectives of polymeric materials as delivery carriers and vaccine adjuvants in the field of drugs and vaccines are presented. With the increase of knowledge and fundamental understandings of polymer-based nanomaterials, means of integrating some other attractive properties, such as slow release, target delivery, and alternative administration methods and delivery pathways are feasible. Polymer-based nanomaterials have great potential for the development of novel vaccines and drug systems for certain needs, including single-dose and needle-free deliveries of vaccine antigens and drugs in the future.

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Chemically induced graft copolymerization of 2-hydroxyethyl methacrylate onto polyurethane surface for improving blood compatibility

Cited by 81 publications

References 25 publications

Polyurethane membrane functionalization with the grafted cellulose derivatives to control water vapor permeability

Polyurethane membrane functionalization with the grafted cellulose derivatives to control water vapor permeability

Evaluation of polyurethane based on cellulose derivative-ketoprofen biosystem for implant biomedical devices

Polymer-Based Nanomaterials and Applications for Vaccines and Drugs

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