Chemically Grown MoO3 Nanorods for Antibacterial Activity Study

Abstract

In the present investigation, sea urchin like morphology of h-MoO 3 nanorods are successfully synthesized by chemical bath deposition (CBD) technique. The thermal stability, structural details, morphology and compositional analysis of MoO 3 was done using thermogravimetry (TGA), X-ray diffraction (XRD), scanning electron microscopy (SEM), high resolution transmission electron microscopy (HR-TEM), selected area electron diffraction (SAED) and X-ray photoelectron spectroscopy (XPS) techniques respectively. The thermal analysis reveals presence of sharp exothermic peak at 409ºC indicating irreversible phase transition. X-ray diffraction pattern showed hexagonal to orthorhombic phase transition after annealing at 450ºC. As synthesized h-MoO 3 shows well oriented hexagonal rods with sea urchin like architecture while that of annealed MoO 3 sample revealed 2D layer by layer growth. The SAED pattern confirms single crystalline nature of as synthesized h-MoO 3 and polycrystalline nature of annealed α-MoO 3 . While XPS study of both confirms Mo +6 and O 2-oxidation states of elements. Furthermore, characteristic antibacterial properties of h-MoO 3 and α-MoO 3 against gram positive Bacillus megaterium, Streptococcus aureus and gram negative Escherichia coli is noted.

Albumin Carriers for Cancer Theranostics: A Conventional Platform with New Promise

“…According to Sudlow's nomenclature, HSA appears to have two specific drug‐binding sites, namely site I (also called the warfarin binding site) and site II (the benzodiazepine binding site) . Consequently, to improve the pharmacokinetic profile and the therapeutic efficiency, and reduce the side effects of drugs, different types of chemotherapeutic drugs, anti‐inflammatory drugs, hypoglycemic drugs, and a number of other types, may have high affinity to the two binding sites of HSA. After loading with drug molecules, especially water‐insoluble ones such as PTX, nanoparticles with sizes in the range of 50–150 nm are often formed owing to the self‐assembly of many albumin proteins into a single nanoparticle…”

Effects of cerium and tungsten substitution on antiviral and antibacterial properties of lanthanum molybdate

“…We specifically examined the hydrophobicity of rare-earth oxides [ [8] , [9] , [10] , [11] , [12] ] and antibacterial effects of molybdenum [ [13] , [14] , [15] , [16] ]. Then we developed the complex oxide La 2 Mo 2 O 9 (hereinafter LMO) using polymerizable complex method [ 17 ].…”

Multifunctional Albumin Nanoparticles As Combination Drug Carriers for Intra‐Tumoral Chemotherapy

“…Clinically‐used ANPs ( nab‐ paclitaxel, Abraxane, Abraxis BioScience Inc.)38, 39 have already been shown to sequester large amounts of therapeutic cargo,40, 41 improve the pharmacokinetics and circulation half‐life of antitumor agents,42 reduce in vivo toxicity associated with solvent delivery systems21 and possibly enhance tumor uptake of therapeutics via albumin binding interactions 43–45. However, ANPs exhibit limited penetration into tumors and have not yet been reported to deliver a combination of synergistic chemotherapeutics simultaneously.…”