Chemically Functionalized Water Soluble Single-Walled Carbon Nanotubes Modulate Neurite Outgrowth

Ni, Yingchun; Hu, Hui; Malarkey, Erik B.; Zhao, Bin; Montana, Vedrana; Haddon, Robert C.; Parpura, Vladimir

doi:10.1166/jnn.2005.189

Cited by 133 publications

(130 citation statements)

References 0 publications

Supporting

Mentioning

129

Contrasting

Order By: Relevance

“…They concluded that more positively charged groups incite greater neurite length and more numerous growth cones. 146 Gabay et al showed that softlithography techniques could be coupled with CNT growth in order to create nanotopographical surfaces, allowing greater control in cell growth and attachment. Neurons aggregated and accumulated in CNT-coated regions, while the rest of the quartz substrate had very low cell density.…”

Section: Cnt and Neuron Interactionmentioning

confidence: 99%

Carbon nanotube interaction with extracellular matrix proteins producing scaffolds for tissue engineering

Tonelli¹,

Santos²,

Gomes³

et al. 2012

IJN

View full text Add to dashboard Cite

Abstract:In recent years, significant progress has been made in organ transplantation, surgical reconstruction, and the use of artificial prostheses to treat the loss or failure of an organ or bone tissue. In recent years, considerable attention has been given to carbon nanotubes and collagen composite materials and their applications in the field of tissue engineering due to their minimal foreign-body reactions, an intrinsic antibacterial nature, biocompatibility, biodegradability, and the ability to be molded into various geometries and forms such as porous structures, suitable for cell ingrowth, proliferation, and differentiation. Recently, grafted collagen and some other natural and synthetic polymers with carbon nanotubes have been incorporated to increase the mechanical strength of these composites. Carbon nanotube composites are thus emerging as potential materials for artificial bone and bone regeneration in tissue engineering.

show abstract

Section: Cnt and Neuron Interactionmentioning

confidence: 99%

Carbon nanotube interaction with extracellular matrix proteins producing scaffolds for tissue engineering

Tonelli¹,

Santos²,

Gomes³

et al. 2012

IJN

View full text Add to dashboard Cite

show abstract

“…Recently we obtained evidence indicating that enticement of peripheral nerve regeneration through a non-obstructive multielectrode array (MEA), either after acute or chronic nerve amputation, offers a viable alternative to obtain early neural recordings and long-term interfacing of nerve activity (unpublished data). We and others have also demonstrated that neurons grow onto pristine CNTs at rates comparable to the most permissive lamincoated substrates and that chemically modified CNTs offer a viable substrate for neuron recording and stimulation in vitro ( Figure 1) [11][12][13][14]. Furthermore, CNT-gold or CNT-polypyrrole coating of platinum electrodes, enhances the electrical performance of the electrodes up to 45 fold by decreasing the impedance and increasing the sensitivity and charge storage capacity ( Figure 2) [15].…”

Section: Electrode Design With Cntsmentioning

confidence: 85%

Carbon nanotube coated high-throughput neurointerfaces in assistive environments

Romero-Ortega

Butt

Iqbal

2009

Proceedings of the 2nd International Conference on PErvasive Technologies Related to Assistive Environments

View full text Add to dashboard Cite

Loosing motor activity due to impaired or damaged nerves or muscles affects millions of people world-wide. The resulting lack of mobility and/or impaired communication bears enormous personal, economical and social costs. While several assistive technologies exist, they rely on device surrogates to compensate for the lack of movement and thus provide limited utility and unnatural interface with the user. The ability of interfacing populations of neurons with super high-density multielectrode arrays (SD-MEA) can provide the sensing from and control of bionics devices by thought. Here we propose a neurointerfacing approach using SD-MEAs coated with carbon nanotubes and high-speed computing to overcome latency and long-term electrical viability bottlenecks that are essential in assistive environments. The proposed approach provides ability for fast integration of recording/stimulation from thousands of individually addressable electrodes, while coordinating a real-time computing approach to register, recognize, analyze and respond appropriately to the biological signals from the motor neurons and sensory signals from the robotic prosthesis.

show abstract

“…The authors speculated that the CNTs blocked the channel pore and thus influenced ionic permeability through the membrane. Significant increase in cytoplasmic calcium ions after neurons were depolarized via single-walled CNT (SWCNT) was also reported (Ni et al, 2005). Carboxyl (COOH)-terminated MWCNTs interacted like an antagonist towards three kinds of potassium channels expressed on undifferentiated PC12 cells (Xu et al, 2009).…”

Section: Issues Associated With Cnts As Neural Electrodesmentioning

confidence: 87%

Implantable Electrodes with Carbon Nanotube Coatings

Minnikanti¹,

Peixoto²

2011

Carbon Nanotubes Applications on Electron Devices

View full text Add to dashboard Cite

Chemically Functionalized Water Soluble Single-Walled Carbon Nanotubes Modulate Neurite Outgrowth

Cited by 133 publications

References 0 publications

Carbon nanotube interaction with extracellular matrix proteins producing scaffolds for tissue engineering

Carbon nanotube interaction with extracellular matrix proteins producing scaffolds for tissue engineering

Carbon nanotube coated high-throughput neurointerfaces in assistive environments

Implantable Electrodes with Carbon Nanotube Coatings

Contact Info

Product

Resources

About