Chemically bonded cyclodextrin stationary phases for liquid chromatographic separation of aromatic compounds

Perphenylcarbamoylated β‐cyclodextrin bonded‐silica particles as chiral stationary phase for enantioseparation by pressure‐assisted capillary electrochromatography

“…The optimized pH for the enantiomer separation was determined to be 4.6, and four chiral solutes were separated into their enantiomers (see Table 1). The enhanced resolution of the enantiomers of Met and propranolol is consistent with the results reported by Fujimura et al [36] and Kawaguchi et al [37]. They highlighted the fact that the presence of two aromatic rings in the chiral solutes may contribute to accentuated resolution because the two aromatic rings can fit better into the cavity of b-CD.…”

Application of Click‐chemistry‐based perphenylcarbamated β‐CD chiral stationary phase in CEC

“…Their popularity is not only due to their special chiral hydrophobic cavity, which affords the remarkable ability in forming inclusion complexes with various organic molecules, but also on account of their low price and chemical stability [16][17][18][19][20][21][22][23]. Perphenylcarbamated b-CD CSPs, which were prepared via amino, urea and Yong Wang Yin Xiao Timothy Thatt Yang Tan à Siu-Choon Ng amido linkage, have proven to be much more effective in enantioseparation of a broad range of racemates [24][25][26]. However, each approach has its own shortcomings such as poor stability in aqueous solution and poor batch-to-batch reproducibility.…”

Separation and Retention Behavior of Aromatic Carboxylic Acid Isomers by High‐Performance‐Liquid‐Chromatography Using β‐Cyclodextrin Bonded Phase with Diamine‐s‐Triazine Moiety

“…[2][3][4][5][6][7][8][9][10][11][12] Separations of the isomers of aromatic carboxylic acids using b-CD bonded phases by HPLC have previously been reported. [7][8][9][13][14][15][16][17][18] In our previous publication, the isomers of the five aromatic carboxylic acids, including toluic acid, aminobenzoic acid, nitrobenzoic acid, hydroxybenzoic acid, and naphthoic acid, were effectively separated on an amine-s-triazine-b-CD bonded phase. 18 With the continuation of our studies, it is of interest to further examine the retention of these analytes on the diamine-s-triazine-b-CD bonded phases, so that the influence of the functionality of the spacer arm of the bonded phase on the retention of the analytes can be evaluated and the retention mechanisms can be better understood.…”