Chemical Variability and Chemotype Concept of Essential Oils from Algerian Wild Plants

Benomari, Fatima Zahra; Sarazin, Mathieu; Chaib, Djamel; Pichette, André; Boumghar, Hinane; Boumghar, Yacine; Djabou, Nassim

doi:10.3390/molecules28114439

Cited by 11 publications

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References 44 publications

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“…Moreover, many studies reported that the chemical composition and essential oils yield depend on age, circadian rhythm, soil, temperature conditions, plant organ, and extraction method, among others ( Benomari et al, 2023 ). Therefore, studies are necessary to analyze the influence of these factors on the chemical variability of essential oils, knowledge of which is essential for applying essential oils for phytotherapeutic purposes.…”

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confidence: 99%

Exploring the impact of seasonal variations on the chemical composition, antinociceptive, and anti-inflammatory properties of Pogostemon heyneanus Benth. essential oil

Santos,

Jerônimo,

Ribeiro

et al. 2024

Front. Pharmacol.

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Background:Pogostemon heyneanus leaves infusions are relevant in ethnopharmacology for treating colds, coughs, headaches, and asthma.Purpose: The essential oil chemical composition of a Pogostemon heyneanus specimen was monthly monitored from October 2021 to July 2022 to evaluate the climatic influences on its yield and chemical composition and antinociceptive, andanti-inflammatory properties.Methods: The leaves, collected monthly over a 10-month period, were submitted to hydrodistillation. The oils obtained were analyzed by gas chromatography coupled to a mass spectrometer and gas chromatography coupled to flame ionization detector. The P. heyneanus essential oil (PhEO) was tested in vivo to evaluate its peripheral analgesic actions through the abdominal writhing test induced by acetic acid, and peripheral analgesia by tail immersion. Neurogenic and inflammatory pain were evaluated by formalin test, and acute oral toxicity of the oil was also verified.Results: PhEO presented 27 chemical constituents with the highest predominance of patchoulol (43.6%–76.9%), α-bulnesene (0.2%–12.7%), α-guaiene (0.4%–8.9%), seychellene (3.8%–5.1%) and pogostol (0.0%–8.2%). The climatic parameters insolation, humidity, rainfall, and temperature did not influence the essential oil yield or the main chemical constituents, except for pogostol, which presented a strong (r = 0.73) and statistically significant (p < 0.05) correlation with temperature. PhEO did not display toxicity at the maximum 300 mg/kg dosage. The oil showed low peripheral and central analgesic action at 100 mg/kg, while in the neurogenic and inflammatory pain inhibition tests, no actions related to PhEO were observed. In the carrageenan-induced peritonitis test, PhEO did not reduce the migration of leukocytes to the peritoneal cavity compared to the control group.Conclusion:Pogostemon heyneanus is a resistant plant to seasonal influences and a source of patchoulol. Despite ethnopharmacological indications, no in-vivo biological activities such as neurogenic or inflammatory pain were identified in the present work. So, the low influence of the climatic parameters on chemical composition can infer that the low pharmacological activity is also not subject to climatic variations, that is, it does not change due to the climate.

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Section: Introductionmentioning

confidence: 99%

Exploring the impact of seasonal variations on the chemical composition, antinociceptive, and anti-inflammatory properties of Pogostemon heyneanus Benth. essential oil

Santos,

Jerônimo,

Ribeiro

et al. 2024

Front. Pharmacol.

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Chemical Variability and Anti‐Inflammatory Activity of Rosmarinus officinalis L. Leaf Essential Oil from Algerian Sahara

Bekhechi,

Malti,

Babali

et al. 2024

Chemistry & Biodiversity

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The chemical composition of 71 oil samples from the leaves of Rosmarinus officinalis L., harvested in three provinces: Naâma (Western Algeria), Béchar and Adrar (Algerian Sahara), was investigated by GC‐FID, GC/MS and 13CNMR. In total, 52 compounds were identified accounting for 88.8 % to 99.9 % of the total composition. The chemical composition of the oils was largely dominated by monoterpenes, with 1,8‐cineole (9.7–70.2 %), camphor (0.3–31.0 %) being the major compounds followed by borneol (0.3–21.0 %), α‐pinene (4.5–14.5 %), β‐pinene (0.1–12.0 %), linalool (0.7–9.9 %) and verbenone (up to 11.1 %) which was present only in the samples harvested in Adrar. All compositions (71 samples) were submitted to statistical analysis. Combination of hierarchical clustering dendrogram and principal component analysis suggested the existence of three groups (one of these being subdivided into two sub‐groups) which were distinguished on the basis of 1,8‐cineole, camphor and verbenone contents. Four essential oil samples, containing 1,8‐cineole and/or camphor as main components, exhibited anti‐inflammatory activity against lipoxygenase, with IC50 values in the range 93 to 155 μg/mL.

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Plant Tissue Culture: Industrial Relevance and Future Directions

Zuzarte,

Salgueiro,

Canhoto

2024

Advances in Biochemical Engineering/Biotechnology

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Chemical Variability and Chemotype Concept of Essential Oils from Algerian Wild Plants

Cited by 11 publications

References 44 publications

Exploring the impact of seasonal variations on the chemical composition, antinociceptive, and anti-inflammatory properties of Pogostemon heyneanus Benth. essential oil

Exploring the impact of seasonal variations on the chemical composition, antinociceptive, and anti-inflammatory properties of Pogostemon heyneanus Benth. essential oil

Chemical Variability and Anti‐Inflammatory Activity of Rosmarinus officinalis L. Leaf Essential Oil from Algerian Sahara

Plant Tissue Culture: Industrial Relevance and Future Directions

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