Chemical vapour deposition polymerization of substituted [2.2]paracyclophanes

Multipotent Polymer Coatings Based on Chemical Vapor Deposition Copolymerization

“…Such a modular surface design may be of great value for future biomedical devices, high-throughput screening platforms, microfluidic analysis devices, or diagnostic platforms. [10]. CVD copolymerization was performed using molar mixtures of 1 and 2 (for the 1:1 feed ratio, we used 38.0 lmol each).…”

“…[9][10][11] This novel coating technology resulted in a diverse class of functionalized poly p-xylylenes containing a wide variety of functional groups such as amines, [12] esters, [13,14] aldehydes, [15] and alcohols. [16] The resulting polymers provide a flexible solution to surface-engineering challenges, as they decouple surface design from bulk properties.…”

“…Prior to CVD copolymerization, 4-trifluoroacetyl [2.2]paracyclophane (1) and 4-aminomethyl-[2.2]paracyclophane (2) were synthesized from commercially available [2.2]paracyclophane following established synthetic routes. [10,19] CVD copolymerization of 1 and 2 was then conducted and resulted in a vacuum-deposited film of copolymer 3 on the substrate (Scheme 1). For CVD copolymerization, mixtures of carefully purified dimers 1 and 2 were initially sublimated under a reduced pressure of 56 Pa at 90-100°C.…”

A Novel Photodefinable Reactive Polymer Coating and Its Use for Microfabrication of Hydrogel Elements

“…[12] Reactive polymer coatings that can be deposited as convergent films on virtually any substrate material provide a flexible solution to surface engineering challenges as they decouple surface design from bulk properties. [13] Recently, chemical vapor deposition (CVD) polymerization was used to prepare poly[(p-xylylene carboxylic acid pentafluorophenolester)-co-(p-xylylene)] [14] and poly(p-xylylene-2,3-dicarboxylic acid anhydride), [15] the first members of a novel class of functionalized poly(p-xylylenes) that may be referred to as reactive coatings. The high chemical reactivity of their functional groups supported rapid conversion with binding partners; even without further chemical activation.…”

Interaction of Insulin and Polymer Surface Investigated by Surface-MALDI-TOF-Mass Spectrometry

“…[17] Briefly the monomer 4-Amino[2.2]-paracyclophane was pyrolyzed at 650 °C under reduced pressure and than condensed at 18 °C on PVDF. After the procedure we had surfaces coated with poly[oamino-p-xylylene-co-p-xylylene] (PVDF-CVD).…”