Chemical Studies of Cremanthodium (Asteraceae) Species; Sesquiterpenoids and Related Compounds

Abstract

Chemical constituents of Cremanthodium angustifolium, C. brunneopilosum, C. campanulatum, C. daochengense, C. discoideum, C. ellisii, C. helianthus, C. lineare, C. nobile, C. potaninii, C. principis, C. pulchrum, C. rhodocephalum, C. stenactinium, C. pleurocaule, and C. stenoglossum were reviewed. They produced mainly sesquiterpenoids–bicyclic and/or tricyclic eremophilanes, bisabolanes, bakkanes–and related compounds. Cremanthodium was shown to be close to Ligularia in chemical constituents.

New Benzofuran Oligomers from the Roots of Eupatorium heterophyllum Collected in China

“…Plausible biosynthetic pathways for the new benzofuran oligomers (1)(2)(3)(4)(5) are depicted in Scheme 1. Compound 1 can be a homocoupling product of two ortho-radicals generated by one-electron oxidation of known compound 29.…”

“…Plants in the Hengduan mountains area are useful for studying plant diversity and evolution. We have been studying inter-and intra-specific diversity in chemical constituents of some Asteraceae plants growing in this area, including Ligularia [1,2], Cremanthodium [3], Saussurea [4,5], and Eupatorium [6][7][8][9]. To date, the presence of intra-specific diversity has been discovered at various levels in most species, affording numerous new compounds produced by limited populations within a species.…”

“…In this study, two additional root samples of E. heterophyllum were collected at different locations in Yunnan Province of China as part of our ongoing research into the chemical diversity of the genus Eupatorium. Fifteen new compounds, including five benzofuran oligomers (1)(2)(3)(4)(5), were isolated from the MeOH extract of the roots of the collected samples. Herein, we report the isolation and structural elucidation of these compounds.…”

The natural hybridization between speciesLigularia nelumbifoliaandCremanthodium stenoglossum(Senecioneae, Asteraceae) suggests underdeveloped reproductive isolation and ambiguous intergeneric boundary

“…In Ligularia , many species occur together with overlapping flowering periods, and natural hybridization has frequently been observed ( Pan et al 2008 ; Yu et al 2011 , 2014a, b ; Pante et al 2015 ; Zhang et al 2018a ), whereas little is known about hybridization in Cremanthodium . In recent years, studies on Cremanthodium have focused on its chemical composition and the description of new species ( Wang et al 2018 ; Fei et al 2019 ; Tori et al 2019 ). Meanwhile, intergeneric hybridization within Asteraceae is rarely reported.…”