Chemical Sensors

Fraden, Jacob

doi:10.1007/978-1-4419-6466-3_17

Cited by 6 publications

(10 citation statements)

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“…A chemical FET can also possess a gas-selective coating/a series of coatings, between the transistor gate and the analyte. Different chemical modification of the gate allows reaction with different chemical species hence permitting their differentiation [ 43 , 143 ]. For ion sensitive FETs charged species at the sensing interface of the gate, change the polarization of the underlying semiconductor/dielectric interface.…”

Section: Types Of Nanomaterial-based Sensors In Breath Analysismentioning

confidence: 99%

“…Electrochemical sensors are divided into potentiometric (voltage measurement), amperometric (electric current measurement), or conductometric (conductivity or resistivity measurement) [ 143 ]. Analyte detection occurs on appropriate electrodes on which a chemical reaction (oxidation or reduction) takes place.…”

Section: Types Of Nanomaterial-based Sensors In Breath Analysismentioning

confidence: 99%

“…Electrochemical sensors typically consist of a sensing (working) electrode and a counter electrode separated by a thin layer of electrolyte [ 51 ]. The sensing electrode, on which the reaction occurs, is characterized by high surface-to-volume ratio (for signal enhancement) and is composed of catalytic materials, e.g., platinum, palladium, or carbon-coated metals [ 143 ] that are specific for the desired analyte [ 51 ]. Analyte-electrode reaction generates a sufficient electrical signal [ 51 ] measured with respect to the counter electrode [ 143 ].…”

Section: Types Of Nanomaterial-based Sensors In Breath Analysismentioning

confidence: 99%

“…The sensing electrode, on which the reaction occurs, is characterized by high surface-to-volume ratio (for signal enhancement) and is composed of catalytic materials, e.g., platinum, palladium, or carbon-coated metals [ 143 ] that are specific for the desired analyte [ 51 ]. Analyte-electrode reaction generates a sufficient electrical signal [ 51 ] measured with respect to the counter electrode [ 143 ]. A schematic representation of electrochemical sensors is presented in Figure 4 .…”

Section: Types Of Nanomaterial-based Sensors In Breath Analysismentioning

confidence: 99%

“…Acoustic wave devices are used in piezoelectric sensors, also called mass, gravimetric, or microbalance sensors. An oscillating circuit is used for the generation of acoustic waves, allowing the piezoelectric crystal to resonate [ 143 ]. The most important categories of piezoelectric gas sensors are QCM and SAW [ 40 ].…”

Section: Types Of Nanomaterial-based Sensors In Breath Analysismentioning

confidence: 99%

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Breath Analysis: A Promising Tool for Disease Diagnosis—The Role of Sensors

Kaloumenou

Skotadis

Lаgopati

et al. 2022

Sensors

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Early-stage disease diagnosis is of particular importance for effective patient identification as well as their treatment. Lack of patient compliance for the existing diagnostic methods, however, limits prompt diagnosis, rendering the development of non-invasive diagnostic tools mandatory. One of the most promising non-invasive diagnostic methods that has also attracted great research interest during the last years is breath analysis; the method detects gas-analytes such as exhaled volatile organic compounds (VOCs) and inorganic gases that are considered to be important biomarkers for various disease-types. The diagnostic ability of gas-pattern detection using analytical techniques and especially sensors has been widely discussed in the literature; however, the incorporation of novel nanomaterials in sensor-development has also proved to enhance sensor performance, for both selective and cross-reactive applications. The aim of the first part of this review is to provide an up-to-date overview of the main categories of sensors studied for disease diagnosis applications via the detection of exhaled gas-analytes and to highlight the role of nanomaterials. The second and most novel part of this review concentrates on the remarkable applicability of breath analysis in differential diagnosis, phenotyping, and the staging of several disease-types, which are currently amongst the most pressing challenges in the field.

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Section: Types Of Nanomaterial-based Sensors In Breath Analysismentioning

confidence: 99%

Section: Types Of Nanomaterial-based Sensors In Breath Analysismentioning

confidence: 99%