Chemical Profile of the Sulphated Saponins from the Starfish Luidia senegalensis Collected as by-Catch Fauna in Brazilian Coast

Abstract

The by-catch fauna of the shrimp fishery includes a number of marine invertebrates that are discarded because they do not have commercial value. In order to try to add some value to these materials, we analyzed the chemical composition of the starfish Luidia senegalensis collected in the Brazilian coast as a consequence of the trawling fishery method. In order to access their chemical composition, we used a combination of solid phase extraction (SPE) followed by ultra-high performance liquid chromatography coupled to electrospray ionization ion trap tandem mass spectrometry (UPLC-ESI-IT-MSn). Luidia senegalensis contains asterosaponins, which are sulphated glycosilated steroids, containing five and six sugar moieties, in addition to polyhydroxysteroids. This study helped us to support the presence of important and potentially bioactive compounds in invertebrates associated to the by-catch fauna of the shrimp fishery, using a fast and efficient method.Graphical Abstract

Marine natural products and human immunity: novel biomedical resources for anti-infection of SARS-CoV-2 and related cardiovascular disease

“…In recent years, a series of literatures published in Natural Products and Bioprospecting showed that MNPs including Ascidians [ 172 ], brown algae [ 173 ], invertebrates [ 174 ], soft corals [ 175 ], some marine animals and creatures (e.g., salmon, shrimp, trout, krill, crayfish, microalgae Heamatococcus pluvialis, Chlorococcum, Chlorella zofingiensis) [ 176 ], and marine sponges [ 177 ] have exhibited a strong antimicrobial activity [ 173 ], with important and potentially bioactive compounds [ 174 ], for example, Astaxanthin [ 176 ], Cembranoids [ 175 ], and Terpenes [ 177 ], and have a broad range of biological activities, and present a huge potential for the development of various drugs for its remarkable bioactivities against mNCDs (such as CVD, cancer, diabetes, neurodegenerative and immune disorders, and others) due to a series of anti-aging [ 178 ], antioxidant, anti-inflammatory, anti-cancer, anti-diabetic, anti-obese, anti-viral (COVID-19 infection), neuro- & nephro-protective, and fertility-enhancing properties. Here, this article also summarized MNPs-derived bioactive compounds and/or targets, their chemical structures, and related potentials on human diseases (Table 2 ).…”

Application of MS-Based Metabolomic Approaches in Analysis of Starfish and Sea Cucumber Bioactive Compounds

“…A combination of SPE and ultra-high performance liquid chromatography (UPLC) coupled with ion trap (IT) mass spectrometry was used to profile asterosaponins from the Brazilian starfish Luidia senegalensis [ 88 ]. Seven components were detected as a result, and five of which were characterized as asterosaponins.…”