Chemical peels: A review of current practice

O'Connor, Alicia A; Lowe, Patricia; Shumack, Stephen; Lim, Adrian

doi:10.1111/ajd.12715

Cited by 77 publications

(125 citation statements)

References 57 publications

(152 reference statements)

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“…Additionally, the sensations of pain and itching can overlap in both AD and psoriasis, even if different neural pathways are involved. Similar to chronic inflammatory diseases, dermatological procedures, such as laser treatment, chemical peels and photodynamic therapy, also disrupt the skin barrier and are associated with cutaneous pain 12,13 …”

Section: Introductionmentioning

confidence: 99%

A spray containing extracts of oat plantlets and Uncaria tomentosa relieves pain associated with chronic inflammatory skin diseases and dermatological procedures

Reich

Estebaranz

Bahadoran

et al. 2020

Acad Dermatol Venereol

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Background Inflammation from skin conditions such as psoriasis, eczema‐like atopic dermatitis (AD) and hand eczema (HE) and following dermatological procedures (post‐acts) can result in intense itching and cutaneous pain. Dermo‐cosmetics containing plant extracts have been shown to reduce or alleviate these symptoms. Objectives Assessment of the tolerability and efficacy of a spray containing Rhealba\xAE Oat plantlets and Uncaria tomentosa extracts in adults and children with inflammatory skin diseases and after dermatological procedures. Methods Data from five open label studies were analysed (Study 1: adults with AD; Study 2: children with AD; Study 3: adults with psoriasis; Study 4: adults with HE; Study 5: adults who had undergone a dermatological procedure: laser, intense pulsed light, glycolic acid peeling, photodynamic therapy or cryotherapy procedure). In all studies, subjects could use the test product up to six times per day for symptom relief. Physical and functional signs of inflammation, treatment‐emergent adverse events (TEAEs), soothing effect, changes in quality of life, cutaneous pain and cosmetic acceptability were compared pre‐ and postapplication. Results A total of 176 subjects were enrolled across the five studies. Overall, investigators judged the dermatological tolerance of the test product containing Rhealba\xAE Oat plantlets extract and Uncaria tomentosa as good to excellent. All studies showed significant improvements in physical signs, reduction in itching and feeling of pain (P < 0.05). The soothing effect was evident after the first application. TEAEs were mostly mild, transient and occurred within the first few days of treatment. The majority of subjects reported improved QoL across the studies. Conclusions The dermo‐cosmetic spray containing Rhealba\xAE Oat plantlets extract and U. tomentosa was well tolerated and efficacious in providing relief of symptoms associated with cutaneous pain from inflammatory skin diseases and following dermatological procedures; however, further studies are needed to rule out alternative explanations of symptom reduction such as natural history and response biases.

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Section: Introductionmentioning

confidence: 99%

A spray containing extracts of oat plantlets and Uncaria tomentosa relieves pain associated with chronic inflammatory skin diseases and dermatological procedures

Reich

Estebaranz

Bahadoran

et al. 2020

Acad Dermatol Venereol

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“…Research states that Fox mentions a 20% phenol solution to lighten the skin in 1871 . We were not able to verify that.…”

Section: Discussionmentioning

confidence: 99%

“…Statistics for Germany and Italy reveal that chemical peeling procedures are among the top three non‐surgical facial rejuvenation procedures in these countries . Since there is an increasing number of treatments with chemical peelings worldwide in recent years, the interest in the history of chemical peeling and its agents has also grown . To know where therapies come from and how substances were found for their right use, the history of the most effective chemical peeling agents is most interesting.…”

Section: Introductionmentioning

confidence: 99%

The rise of Chemical Peeling in 19th‐century European Dermatology: emergence of agents, formulations and treatments

Borelli

Ursin

Steger

2020

Acad Dermatol Venereol

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Background Considering the increasing number of chemical peeling applications, also the interest in the history of chemical peelings and agents, has grown in dermatology. Research ascribes the first use of phenol as a chemical peeling agent to William Tilbury Fox (1836–1879) in 1871. Furthermore, Ferdinand von Hebra (1847–1902) is said to describe the properties of various peeling agents in 1874, and Paul Gerson Unna (1850–1929) adds resorcinol and trichloroacetic acid in 1882. Objective To identify the first mentions of chemical peeling applications and agents in 19th‐century dermatology. Methods Nineteenth‐century dermatologists were identified by an examination of literature of the last 30 years on the history of chemical peeling. Systematic examination of the medical textbooks of Hebra, Fox and Unna was conducted. It was proved whether the mentioned agents were used for chemical peeling applications. Results The skin peeling property of phenol was already discovered by its first describer, the chemist Friedlieb Ferdinand Runge (1795–1867) in 1834. The Viennese dermatologist Hebra described phenol as a chemical peeling agent in 1860. Hebra and his associate Moriz Kaposi (1837–1902) stated that ‘Lotio carbolica’ was already used in London. Fox used phenol mostly as a disinfectant and not for chemical peelings since 1869. Unna described the chemical peeling property of salicylic acid in 1882 and gave the most comprehensive account of chemical peels of the 19th century in 1899. Unna also introduced the Gutta‐percha plaster with salicylic acid and phenol. Around 1900, Unna was famous for his peeling paste with resorcinol in Germany. Conclusions A new chronology of the introduction of chemical peeling in dermatology can be drawn from the results. The German‐speaking dermatology pioneered the treatment of skin diseases with chemical peelings as well as for aesthetical purposes 21 years earlier than hitherto known.

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“…Pretreatment improves skin tolerance, regulates fibroblast and melanocyte function, improves dermal circulation, and allows for the treated skin to heal 3–4 days faster due to increased cellular division and new collagen formation. 1,5,9 Modifications to this preprocedure regimen (dosages and application intervals) are made as needed based on tolerance and skin types. A week before peel, patients are started on a cleansing and toning protocol and encouraged to maintain adequate hydration and moisturize of the skin.…”

Section: Trichloroacetic Acid and Jessner’s Solutionmentioning

confidence: 99%

“…Chemical treatments to enhance facial appearance are among the earliest forms of aesthetic procedures, dating back to ancient Egyptians who used animal oils, salt, alabaster, and sour milk to improve the skin. 1 Today, a variety of formulations and concentrations are used to treat conditions such as dyschromias, rhytids, actinic changes, and keratosis. 2 The type of chemical peel is often selected based on depth of penetration required to effectively treat a given condition.…”

mentioning

confidence: 99%

Jessner’s Solution with Trichloroacetic Acid Chemical Peel: Optimizing Outcomes and Safety

Dayan

Rohrich

2019

Plastic and Reconstructive Surgery - Global Open

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Chemical peels: A review of current practice

Cited by 77 publications

References 57 publications

A spray containing extracts of oat plantlets and Uncaria tomentosa relieves pain associated with chronic inflammatory skin diseases and dermatological procedures

A spray containing extracts of oat plantlets and Uncaria tomentosa relieves pain associated with chronic inflammatory skin diseases and dermatological procedures

The rise of Chemical Peeling in 19th‐century European Dermatology: emergence of agents, formulations and treatments

Jessner’s Solution with Trichloroacetic Acid Chemical Peel: Optimizing Outcomes and Safety

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