“…[92][93][94][95][96][97][98] Molecular organic transformations with heterogeneous catalystimmobilized flow microreactors are representative examples of these systems, where the efficiency of various organic transformations has been found to increase due to the vast interfacial area and the close distance of the molecular diffusion path in the narrow space of the flow microreactor. [99][100][101][102][103][104][105][106][107][108][109][110] If a heterogeneous catalyst was immobilized as a membranous composite at the interface of an organic layer and aqueous layer (the center of the microchannel), two reactants could be oppositely charged into and flow through the divided channel, all the while in contact with the vast interfacial surface of the catalytic membrane from both front and back sides, thereby realizing an instantaneous chemical reaction.…”
Section: Development Of Catalytic Membrane-installed Microflow Reactomentioning
My mission in catalysis research is to develop highly active and reusable supported catalytic systems in terms of fundamental chemistry and industrial application. For this purpose, I developed three types of highly active and reusable supported catalytic systems. The first type involves polymeric base-supported metal catalysts: Novel polymeric imidazole-Pd and Cu complexes were developed that worked at the mol ppm level for a variety of organic transformations. The second involves catalytic membrane-installed microflow reactors: Membranous polymeric palladium and copper complex/nanoparticle catalysts were installed at the center of a microtube to produce novel catalytic membrane-immobilized flow microreactor devices. These catalytic devices mediated a variety of organic transformations to afford the corresponding products in high yield within 1-38 s. The third is a silicon nanowire array-immobilized palladium nanoparticle catalyst. This device promoted a variety of organic transformations as a heterogeneous catalyst. The Mizoroki-Heck reaction proceeded with 280 mol ppb (0.000028 mol%) of the catalyst, affording the corresponding products in high yield.
“…[92][93][94][95][96][97][98] Molecular organic transformations with heterogeneous catalystimmobilized flow microreactors are representative examples of these systems, where the efficiency of various organic transformations has been found to increase due to the vast interfacial area and the close distance of the molecular diffusion path in the narrow space of the flow microreactor. [99][100][101][102][103][104][105][106][107][108][109][110] If a heterogeneous catalyst was immobilized as a membranous composite at the interface of an organic layer and aqueous layer (the center of the microchannel), two reactants could be oppositely charged into and flow through the divided channel, all the while in contact with the vast interfacial surface of the catalytic membrane from both front and back sides, thereby realizing an instantaneous chemical reaction.…”
Section: Development Of Catalytic Membrane-installed Microflow Reactomentioning
My mission in catalysis research is to develop highly active and reusable supported catalytic systems in terms of fundamental chemistry and industrial application. For this purpose, I developed three types of highly active and reusable supported catalytic systems. The first type involves polymeric base-supported metal catalysts: Novel polymeric imidazole-Pd and Cu complexes were developed that worked at the mol ppm level for a variety of organic transformations. The second involves catalytic membrane-installed microflow reactors: Membranous polymeric palladium and copper complex/nanoparticle catalysts were installed at the center of a microtube to produce novel catalytic membrane-immobilized flow microreactor devices. These catalytic devices mediated a variety of organic transformations to afford the corresponding products in high yield within 1-38 s. The third is a silicon nanowire array-immobilized palladium nanoparticle catalyst. This device promoted a variety of organic transformations as a heterogeneous catalyst. The Mizoroki-Heck reaction proceeded with 280 mol ppb (0.000028 mol%) of the catalyst, affording the corresponding products in high yield.
“…[10,37,40] Die kleinen Reaktorvolumina (nL-mL) gewährleisten einen geringen Reagentienverbrauch und eine schnelle Reaktion auf Systemstörungen, was eine kurzfristige Anpassung der Versuchsbedingungen zur Abstimmung der Materialeigenschaften in Echtzeit ermög-licht. [41] Eine Integration von Chemikaliendetektoren im Mikrofluidiksystem würde ein Screening des chemischen Prozesses unter kontrollierten Bedingungen und mit einem hohen Durchsatz gestatten, was in konventionellen makroskopischen Systemen oft schwierig ist. [39] hängiger Reaktionen zur Synthese neuer Verbindungen durchgeführt werden kann.…”
Section: Mikrofluidik Mikromischer Und Mikroreaktorenunclassified
In den letzten Jahren hat die Mikrofluidik in der Chemie stark an Bedeutung gewonnen. Miniaturisierte chemische Vorrichtungen ermöglichen einen kontrollierten Flüssigkeitstransport und schnelle chemische Reaktionen und sind darüber hinaus Kosten sparend, wenn man sie mit konventionellen Reaktoren vergleicht. Sowohl in der (Bio‐)Analytik als auch in der organischen Synthese werden diese Vorteile bereits ausgiebig genutzt, weniger hingegen in der anorganische Chemie und den Materialwissenschaften. Dennoch wird diese Thematik auch in der Anorganik bei der Entwicklung von Mikroreaktoren für die Trennung und selektive Extraktion von Metallionen gestreift. Bei Funktionsmaterialien wird die Mikrofluidik hauptsächlich für Verbesserungen in der Synthese von Nanopartikeln (besonders von Metall‐, Metalloxid‐ und Halbleiternanopartikeln) eingesetzt. Mikrofluidiktechniken können auch für die Entwicklung von komplizierteren anorganischen (Hybrid‐)Materialien genutzt werden.
“…Whereas a reaction in a flask or batch vessel usually takes several hours, the same reaction can be carried out here in seconds to minutes. Pennemann et al [13] compare the reaction times and conversions of different reactions. The comparison in Table 1 1.1. shows that a significant change in the magnitude of reaction times may be observed.…”
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