2020
DOI: 10.22146/ijc.46643
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Chemical Investigation and Antimicrobial Activity of Medicinal Plant <i>Toddalia asiatica</i> Lam

Abstract: Medicinal plants have become important sources of natural products, which have been used in the development of therapeutic agents. Four new coumarins (1-4) have been isolated together with five known metabolites (5-9) from the medicinal plant T. asiatica. The structures of 1-9 were assigned based on their spectroscopic data. Compounds (1-9) inhibited the growth of the Gram-negative bacteria E. coli and Gram-positive bacteria S. aureus at a concentration of 25 and 50 μg/disc. Compounds (2-4) inhibited the phyto… Show more

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Cited by 4 publications
(4 citation statements)
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“…The results of this assay are presented in Table 4. All most all the methanol and ethanol extract were showed significant Biofilm reduction as compared to negative control except for ethanol and methanol extract of Taza The Indian Tea ++ +++ DISCUSSION: Green tea is one of the most popular beverages worldwide due to its healthpromoting properties, which reflect the presence of antioxidants and also antimicrobial substances that are active against various Gram-positive and Gramnegative bacteria [12][13][14][15][16] . Both activities are mainly due to polyphenols, the most abundant of which is the catechins, particularly epigallocatechin gallate (EGCG), representing 50-80% of the total catechin content 17 .…”
Section: Resultsmentioning
confidence: 99%
“…The results of this assay are presented in Table 4. All most all the methanol and ethanol extract were showed significant Biofilm reduction as compared to negative control except for ethanol and methanol extract of Taza The Indian Tea ++ +++ DISCUSSION: Green tea is one of the most popular beverages worldwide due to its healthpromoting properties, which reflect the presence of antioxidants and also antimicrobial substances that are active against various Gram-positive and Gramnegative bacteria [12][13][14][15][16] . Both activities are mainly due to polyphenols, the most abundant of which is the catechins, particularly epigallocatechin gallate (EGCG), representing 50-80% of the total catechin content 17 .…”
Section: Resultsmentioning
confidence: 99%
“…Oleh karena itu, pencarian senyawa antibakteri yang berasal dari alam terus dilakukan. [4][5][6][7][8][9][10][10][11][12][13][14][15][16] . Penelitian tentang antibakteri yang berasal daun awar-awar telah dilaporkan 17 , namun sejauh ini belum ada informasi tentang ekstrak buah awar-awar sebagai anti bakteri.…”
Section: Pendahuluanunclassified
“…It is known that plants that have been used in the treatment of diseases for a very long time have various biological activities (Li et al, 2020). These biological activities; such as antimicrobial, antioxidant, analgesic, antiproliferative, anticancer, antiallergic, antihypertensive (Pehlivan et al, 2018;Sevindik, 2018;Fujitaka et al, 2020;Lisa et al, 2020;Maarisit and Lawani, 2020;Ng et al, 2020;Chen et al, 2021). Today, with the use of advanced instrumental methods, it is possible to isolate the components found in plant tissues, even in traces, and to determine their biological activities by making qualitative and quantitative analyzes .…”
Section: Introductionmentioning
confidence: 99%