“…Many uses have been developed and suggested for piperazine derivatives (4, 8). Leng (9) describes an analytical method for determining piperazine in feeds, which, however, requires rather large samples and is too long for routine use. Cavett (2) and Perlmutter (70) investigated a method of analysis which uses steam distillation to isolate the piperazine and an acid medium for color development between the drug and /¡-quinone.…”