Chemical constituents, pharmacological activities, and uses of common ayurvedic medicinal plants: a future source of new drugs

LC-HRMS analysis of corn mint Mentha arvensis L. for anticancer activity against triple-negative breast cancer targeting inflammatory and apoptosis signaling pathways

“…8 Menthol obtained from M. arvensis is used in medicine for stomach disorders, ointments for headaches, anti-peptic, and ulcer agents, and has been used for the treatment of skin diseases and throat and nose infections in traditional medicine. 9,10 M. arvensis has traditionally been used for the treatment of various health disorders and has shown antiinflammatory activity against arthritis problems 11,12 arousing the curiosity to utilize the plant for curing other diseases, such as cancer and diabetes. Since the antidiabetic activity of M. arvensis has already been reported, 13 the present study was designed to investigate the effect of M. arvensis on anticancer activity against human breast cancer cell lines using various morphological and molecular analyses.…”

Evaluation of Saraca asoca for its Anti‐Tubercular Potential via Molecular Docking and Molecular Dynamics Simulation Studies

“…Ayurvedic and Unani medicine use various parts of the tree as astringents, hemostatics, alexiterics, anthelmintics, antibacterials, demulcents, diuretics, anti‐inflammatory, and CNS depressants. Extracts obtained from the different plant parts of S. asoca have been reported to be used to treat extreme uterus bleeding, gynecological issues, stomach pain, leucorrhoea, irregular menstrual cycles, internal piles, cracks, cancers, chews, bleeding ulcers, skin discoloration, and other conditions [14,15,16] . In the current work, various phytochemicals from S. asoca were examined in‐vitro and computationally to study their bio‐availability and interactions with proteins through ADME methods and docking studies.…”

“…Extracts obtained from the different plant parts of S. asoca have been reported to be used to treat extreme uterus bleeding, gynecological issues, stomach pain, leucorrhoea, irregular menstrual cycles, internal piles, cracks, cancers, chews, bleeding ulcers, skin discoloration, and other conditions. [14,15,16] In the current work, various phytochemicals from S. asoca were examined in-vitro and computationally to study their bio-availability and interactions with proteins through ADME methods and docking studies. Additionally, molecular dynamics (MD) simulations of the promising compounds with selected targets were performed to examine how well these phytocompounds can inhibit target proteins when they interact with them.…”

Antibacterial Activity of Phyto-Chemicals Obtained From Leafextracts of Some Medicinal Plants on Pathogens of Semi-Arid Soil

“…Plants being rich in number of secondary metabolites saponin, alkaloids, flavonoids, steroids, tannins, glycosides, phytosterol and phenolic compounds are identified for the study of their antimicrobial potential and can be used for the treatment against a number of diseases (Nimri et al, 1999;Saxena, 1997;Banso & Adeyemo et al, 2006;Robe & Vanstrden, 1997;Ongaskul et al, 2009;Ansan et al, 2009). Drugs purified from the medicinal plants have been found to be very effec tive against many antibacterial, antifungal, antithrombotic, anti-malarial diseases and have been effective as anticancerous drug (Kaushik and Dhiman, 2000).The use of plant extracts as antimicrobial drugs is becoming very popular and significant, as microbes resistance to the drugs increased rapidly (Banso & Adeyemo et al, 2006;Elbashiti et al, 2010). The plants are very effective against treatment of many infectious diseases and the combination of the sec ondary metabolites is responsible for the physiological action on the body (Joshi et al, 2009;Mishra & Mishra, 2011).…”