Chemical Constituents of the Rhizome of Typhonium giganteum

Chemical composition and antibacterial activities of ethanolic extract from rhizomes and aerial parts of Typhonium lineare Hett. and V.D. Nguyen (Araceae)

“…It was thus able to resist against this bacterial strain [SCOPEL et al, 2013] . In a contrary manner, the bioactivities of three constituents, including 5-(2'-methylpropyl) hydantoin, 5-(4'-hydroxybenzyl) hydantoin and gigantin have not been reported before in which gigantin, a new compound, was isolated from T. giganteum rhizomes [LIU et al, 2014] .…”

“…As a result, there were 6 compounds present in the ethanolic extract of rhizomes and aerial parts of T. lineare with similar molecular weights of the compounds found in previous studies (Table 1). Accordingly, four constituents, including 5-(2-methylpropyl) hydantoin, 5-(4-hydroxybenzyl) hydantoin, cyclo(leucyltyrosyl) and gigantin were found in rhizomes of T. giganteum [LIU et al, 2014] .…”

“…Several Typhonium species have been known for their medicinal uses in Vietnam and many Asian countries, including T. trilobatum, T. flagelliforme, and T. giganteum [CHEN et al, 2001;LAI et al, 2010;MANKARAN et al, 2013;MANNA et al, 2016;PHAM, 2000] . Furthermore, many studies have identified proved phytochemical composition and proved some bioactivities of extracts from the aerial parts and the tuberous rhizomes of many species of Typhonium genus, such as antimicrobial and antioxidant activities [CHEN et al, 2001;LAI et al, 2010;MANKARAN et al, 2013;MANNA et al, 2016;LIU et al, 2014].…”

Novel Antioxidants and α-Glycosidase and Protein Tyrosine Phosphatase 1B Inhibitors from an Endophytic Fungus Penicillium brefeldianum F4a

“…Six known compounds were identified as penialidin A (4), penialidin F (5), myxotrichin C (6), riboflavin (7), indole-3-acetic acid (8), and 2-(4-hydroxy-2-methoxy-6-methylphenyl) acetic acid (9) by comparing their spectroscopic data with the literature (Figure 1) [26][27][28][29][30][31].…”

“…Furthermore, the absolute configuration of 3 was determined by ECD analysis and the calculated ECD curve showed a high degree of similarity to the experimental ECD spectrum of 3a (Figure3), which indicated that the absolute configuration of 3 is 5R. Therefore, compound 3 was characterized as a new skeleton compound and named peniorcinol C.Six known compounds were identified as penialidin A (4), penialidin F (5), myxotrichin C (6), riboflavin(7), indole-3-acetic acid (8), and 2-(4-hydroxy-2-methoxy-6-methylphenyl) acetic acid (9) by comparing their spectroscopic data with the literature (Figure1)[26][27][28][29][30][31].…”