Chemical Constituents of the Flowers of Michelia alba

Chen, C. Y.; Kao, C. L.; Li, W. J.; Yeh, H. C.; Huang, Soon-Cen; Li, H. T.

doi:10.1007/s10600-018-2392-1

Cited by 10 publications

(8 citation statements)

References 12 publications

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“…alba DC. in 2018 . Also in 2011, zizyphusine ( 88 ) was isolated from the seeds of Ziziphus jujuba var.…”

Section: Part 2: Catecholamine Derivatives In Plantsmentioning

confidence: 99%

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Catecholamine Derivatives: Natural Occurrence, Structural Diversity, and Biological Activity

Tang,

Zhao,

Tao

et al. 2023

J. Nat. Prod.

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Catecholamines (CAs) are aromatic amines containing a 3,4-dihydroxyphenyl nucleus and an amine side chain. Representative CAs included the endogenous neurotransmitters epinephrine, norepinephrine, and dopamine. CAs and their derivatives are good resources for the development of sympathomimetic or central nervous system drugs, while they also provide ligands important for G-protein coupled receptor (GPCR) research. CAs are of broad interest in the fields of chemical, biological, medical, and material sciences due to their high adhesive capacities, chemical reactivities, metal-chelating abilities, redox activities, excellent biocompatibilities, and ease of degradability. Herein, we summarize CAs derivatives isolated and identified from microorganisms, plants, insects, and marine invertebrates in recent decades, alongside their wide range of reported biological activities. The aim of this review is to provide an overview of the structural and biological diversities of CAs, the regularity of their natural occurrences, and insights toward future research and development pertinent to this important class of naturally occurring compounds.

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“…alba DC. in 2018 . Also in 2011, zizyphusine ( 88 ) was isolated from the seeds of Ziziphus jujuba var.…”

Section: Part 2: Catecholamine Derivatives In Plantsmentioning

confidence: 99%

“…in 2018. 84 Also in 2011, zizyphusine (88) was isolated from the seeds of Ziziphus jujuba var. spinosa (Bunge) Hu ex H. F. Chow.…”

Section: Plantsmentioning

confidence: 99%

Catecholamine Derivatives: Natural Occurrence, Structural Diversity, and Biological Activity

Tang,

Zhao,

Tao

et al. 2023

J. Nat. Prod.

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“…A total of 42 constituents were identified from the extracts of different plant parts of M. alba ( Supplementary Data S2 ). Out of the total 42 constituents, 19 constituents were isolated from the flower (F), 21 isolated from leaves (L), and 20 from the stem (S) [ 3 , 17 , 18 ]. Different chemical constituents have been identified from various parts of M. alba extracts.…”

Section: Phytochemistrymentioning

confidence: 99%

“…Some of the major compounds discovered include aporphines, amide, benzenoids, and steroids. In 2018, a study by [ 3 ] discovered a new compound named Michelaine (C 16 H 9 NO 4 ) in the flower of M. alba .…”

Section: Phytochemistrymentioning

confidence: 99%

“…Notably, linalool is the primary component found in M. alba which is also found in lavender and jasmine oils [ 2 ] Numerous studies on linalool have reported its anti-cancer, anti-inflammatory, neuroprotective activity, anti-hypertensive activity, anti-ulcer, anti-hypertriglyceridemia, anti-psoriasis, antidepressant, and anti-diarrheal activities. In 2018, a new compound named Michelaine (C 16 H 9 NO 4 ) was discovered from the flower of M. alba [ 3 ]. However, the bioactivities of Michelaine that are uniquely found in M. alba are not established.…”

Section: Introductionmentioning

confidence: 99%

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Phytochemistry, Bioactivities and Traditional Uses of Michelia × alba

et al. 2022

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Michelia × alba (M. alba) is a flowering tree best known for its essential oil, which has long been used as a fragrance ingredient for perfume and cosmetics. In addition, the plant has been used in traditional medicine in Asia and dates back hundreds of years. To date, there is a limited number of publications on the bioactivities of M. alba, which focused on its tyrosinase inhibition, antimicrobial, antidiabetic, anti-inflammatory, and antioxidant activities. Nevertheless, M. alba may have additional unexplored bioactivities associated with its bioactive compounds such as linalool (72.8% in flower oil and 80.1% in leaf oil), α-terpineol (6.04% flower oil), phenylethyl alcohol (2.58% flower oil), β-pinene (2.39% flower oil), and geraniol (1.23% flower oil). Notably, these compounds have previously been reported to exhibit therapeutic activities such as anti-cancer, anti-inflammation, anti-depression, anti-ulcer, anti-hypertriglyceridemia, and anti-hypertensive activities. In this review paper, we examine and discuss the scientific evidence on the phytochemistry, bioactivities, and traditional uses of M. alba. Here, we report a total of 168 M. alba biological compounds and highlight the therapeutic potential of its key bioactive compounds. This review may provide insights into the therapeutic potential of M. alba and its biologically active components for the prevention and treatment of diseases and management of human health and wellness.

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Sesquiterpenoids from the barks and roots of Michelia alba collected in Xuan Mai town, Hanoi City, Viet Nam

Hoai

Luu

Hieu

et al. 2021

Vietnam Journal of Chemistry

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Eight sesquiterpenoids including costunolide (1), parthenolide (2), 11α,13‐dihydroparthenolide (3), 9β‐hydroxy‐dihydroparthenolide (4), (‐)‐bisparthenolidine (5), 11α,13‐dihydro‐β‐cyclocostunolide (6), α‐cadinol (7), magnograndiolide (8) were isolated from the barks and roots of Michelia alba. The structures of these compounds were elucidated by spectroscopic methods (MS, 1D and 2D NMR) and comparison with the reported data. Compounds 5‐8 have been isolated for the first time from Michelia alba.

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Chemical Constituents of the Flowers of Michelia alba

Cited by 10 publications

References 12 publications

Catecholamine Derivatives: Natural Occurrence, Structural Diversity, and Biological Activity

Catecholamine Derivatives: Natural Occurrence, Structural Diversity, and Biological Activity

Phytochemistry, Bioactivities and Traditional Uses of Michelia × alba

Sesquiterpenoids from the barks and roots of Michelia alba collected in Xuan Mai town, Hanoi City, Viet Nam

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