Chemical constituents of Pholidota leveilleana

Yuan, Zhi‐Peng; Zhong, Yu‐Jiao; Su, Xue‐Hui; Li, Congying; Du, Hongjian; Wen, Yaya; Li, Yanfang; Liang, Bing

doi:10.1016/j.bse.2013.03.017

Cited by 8 publications

References 23 publications

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Dihydrophenanthrene Dimers: Why and Where It Is Possible to Isolate Their Precursors

Fabio

Zarrelli

2023

Chemistry & Biodiversity

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An interesting class of compounds of natural origin is dihydrophenanthrene dimers, which are characterized by a series of remarkable biological properties. Considering the hypothesis that each dimer is obtained through a biosynthetic mechanism that involves the coupling of the corresponding radicals of the single dihydrophenanthrene unit, we identified 29 dihydrophenanthrenes. Of these dihydrophenanthrenes, 11 were new compounds that could be isolated from 10 different plant species; 11 had already been identified, but not yet isolated in the 17 different plant species from which the corresponding dimers had been isolated; and 7 were known and had been isolated in the same plant sources of the corresponding dimers. A targeted analysis of several natural extracts from specific plant sources would allow the identification of known or new molecules with potential and/or specific biological activities and, in a final analysis, would confirm the relative biosynthetic mechanism.

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Dihydrophenanthrene Dimers: Why and Where It Is Possible to Isolate Their Precursors

Fabio

Zarrelli

2023

Chemistry & Biodiversity

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Separation and purification of 9,10-dihydrophenanthrenes and bibenzyls fromPholidota chinensisby high-speed countercurrent chromatography

et al. 2015

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Stilbenoids are the main components of leaves and stems of Pholidota chinensis. In the present investigation, high-speed counter-current chromatography was used for the separation and purification of two classes of stilbenoids, namely, bibenzyls and 9,10-dihydrophenanthrenes, on a preparative scale from whole plants of P. chinensis with different solvent systems after silica gel column chromatography fractionation. n-Hexane/ethyl acetate/methanol/water (1.2:1:1:0.8, v/v/v/v) was selected as the optimum solvent system to purify 1-(3,4,5-trimethoxyphenyl)-1',2'-ethanediol (1), coelonin (2), 3,4'-dihydroxy-5,5'-dimethoxybibenzyl (3), and 2,7-dihydroxy-3,4,6-trimethoxy-9,10-dihydrophenanthrene (4). While 2,7-dihydroxy-3,4,6-trimethoxy-9,10-dihydrophenanthrene (5), batatasin III (6), orchinol (7), and 3'-O-methylbatatasin III (8) were purified by n-hexane/ethyl acetate/methanol/water (1.6:0.8:1.2:0.4, v/v/v/v). After the high-speed counter-current chromatography isolation procedure, the purity of all compounds was over 94% assayed by ultra high performance liquid chromatography. The chemical structure identification of all compounds was carried out by mass spectrometry and (1)H and (13)C NMR spectroscopy. To the best of our knowledge, the current investigation is the first study for the separation and purification of bibenzyls and 9,10-dihydrophenanthrenes by high-speed counter-current chromatography from natural resources.

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Bioactive stilbenes from plants

Zhou²,

Li³

2022

Studies in Natural Products Chemistry

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Chemical constituents of Pholidota leveilleana

Cited by 8 publications

References 23 publications

Dihydrophenanthrene Dimers: Why and Where It Is Possible to Isolate Their Precursors

Dihydrophenanthrene Dimers: Why and Where It Is Possible to Isolate Their Precursors

Separation and purification of 9,10-dihydrophenanthrenes and bibenzyls fromPholidota chinensisby high-speed countercurrent chromatography

Bioactive stilbenes from plants

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