Chemical constituents of Euphorbia tirucalli L.

Abstract

Euphorbia tirucalli has not been chemically studied much in Vietnam. This research described the isolation and elucidation of compounds isolated from the plant collected in Binh Thuan. Multiple chromatographic methods were applied, including normal phase silica gel column chromatography and thin-layer chromatography. Seven compounds were isolated and their chemical structures were elucidated by spectroscopic analysis as well as comparing their data with the ones in the literature. They are arjunolic acid (1), eriodictyol (2), quercitrin (3), afzelin (4), scopoletin (5), 3,3′,4- trimethylellagic acid (6), and gallic acid (7). Among them, compound 1 a major component was isolated for the first time in Euphorbia genus, while three compounds 2, 4, and 5 were isolated from this species for the first time.

Phytochemical Screening and Evaluation of Antioxidant Properties and Antimicrobial Activity against Xanthomonas axonopodis of Euphorbia tirucalli Extracts in Binh Thuan Province, Vietnam

“…EA3.2 was run via CC with methanol and afforded three fractions EA3.2.1-3. EA3.2.1 (166.3 mg) was continuously run via CC with the elute of methanol: water (1: 2 to 1: 1, v / v ) to obtain three compounds 1 (20 mg), 2 (4.3 mg) and 3 (4.6 mg) [ 8 ].…”

“…1, 1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assay was according to the protocol described by Blois [ 8 ] and adapted by Brand-Williams et al [ 41 ]. Briefly, 0.5 mL of ethanol containing different concentrations (31.25, 62.50, 125, 250 and 500 µg/mL) of each extract ( v / v ) was mixed with 1.5 mL of DPPH• ethanol solution (6 × 10 −5 M).…”

“…1, 1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assay was according to the protocol described by Blois [8] and adapted by Brand-Williams et al [41]. Briefly, 0.…”

“…In Vietnam, located on the Indochinese peninsula, Southeast Asia, the Pacific coast, E. tirucalli showed the presence of arjunolic acid, eriodictyol, quercitrin, afzelin, scopoletin, 3,3′,4- trimethylellagic acid, and gallic acid [ 8 , 9 ]. Euphorbia tirucalli is used in popular medicine to treat cancer, antibiotics, and antiviral diseases, popularly known as “giao” or “xuong ca” or “san ho xanh” in Vietnam.…”

Structure-Based Virtual Screening and Molecular Dynamics of Phytochemicals Derived from Saudi Medicinal Plants to Identify Potential COVID-19 Therapeutics

“…Quercetin, isokaempferoside, kaempferol-3β-rutinoside, eriodicytol, genistein, cupressuflavone, luteolin 7rutinoside Delonix elata [7] Dodonea angustifolia [8] Eruca sativa [9] Euphoria tirucalli [10] Fiscus benghalensis [11] Juniperus phonicea [12] Mrrrubium vulgare [13] Alkaloids (tropane, quinoline, isoquinoline, indole, pyrrolidine, and protoberberine) (+)-Bicuculine, adlumidiceine, tetrahydroharman, haplotubinone, solanocapsine, solamargine…”