Chemical Constituents from the Stems of Manihot esculenta

Yamei, Pan; Wang, Xiaonan; Chen, Heping; Li, Shun‐Lin; Di, Ying‐Tong; Chen, Duo-Zhi; Guo, Ling‐Li; Hao, Xiao‐Jiang; He, Hongping

doi:10.1007/s13659-015-0052-8

Cited by 6 publications

(4 citation statements)

References 15 publications

(16 reference statements)

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“…Prior research on K. ceratoides has primarily focused on its ecological and physiological traits [ 12 – 15 ], anatomical structure of vegetative organs [ 16 ], chromosome karyotype [ 17 ], application potential [ 18 ], chemical components [ 19 ], and genetic diversity [ 20 ]. For instance, Han et al [ 20 ] used the RAPD (Random Amplified Polymorphic DNA) technique to investigate seven Krascheninnikovia species , uncovering significant distinctions and a wealth of genetic diversity among these species.…”

Section: Introductionmentioning

confidence: 99%

Comparative analysis and characterization of the chloroplast genome of Krascheninnikovia ceratoides (Amarathaceae): a xerophytic semi-shrub exhibiting drought resistance and high-quality traits

Liu,

Zheng,

et al. 2024

BMC Genom Data

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Background Krascheninnikovia ceratoides, a perennial halophytic semi-shrub belonging to the genus Krascheninnikovia (Amarathaceae), possesses noteworthy ecological, nutritional, and economic relevance. This species is primarily distributed across arid, semi-arid, and saline-alkaline regions of the Eurasian continent, encompassing Inner Mongolia, Xinjiang, Qinghai, Gansu, Ningxia, and Tibet. Results We reported the comprehensive chloroplast (cp) genome of K. ceratoides, characterized by a circular conformation spanning 151,968 bp with a GC content of 36.60%. The cp genome encompassed a large single copy (LSC, 84,029 bp), a small single copy (SSC, 19,043 bp), and a pair of inverted repeats (IRs) regions (24,448 bp each). This genome harbored 128 genes and encompassed 150 simple sequence repeats (SSRs). Through comparative analyses involving cp genomes from other Cyclolobeae (Amarathaceae) taxa, we observed that the K. ceratoides cp genome exhibited high conservation, with minor divergence events in protein-coding genes (PCGs) accD, matK, ndhF, ndhK, ycf1, and ycf2. Phylogenetic reconstructions delineated K. ceratoides as the sister taxon to Atriplex, Chenopodium, Dysphania, and Suaeda, thus constituting a robust clade. Intriguingly, nucleotide substitution ratios (Ka/Ks) between K. ceratoides and Dysphania species for ycf1 and ycf2 genes surpassed 1.0, indicating the presence of positive selection pressure on these loci. Conclusions The findings of this study augment the genomic repository for the Amarathaceae family and furnish crucial molecular instruments for subsequent investigations into the ecological adaptation mechanisms of K. ceratoides within desert ecosystems.

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Section: Introductionmentioning

confidence: 99%

Comparative analysis and characterization of the chloroplast genome of Krascheninnikovia ceratoides (Amarathaceae): a xerophytic semi-shrub exhibiting drought resistance and high-quality traits

Liu,

Zheng,

et al. 2024

BMC Genom Data

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“…The isolated compounds were tested for their antimicrobial activity against five bacterial strains ( Pseudomonas aeruginosa ATCC 27853, Enterococcus faecalis ATCC 10541, Escherichia coli ATCC 11775, Staphylococcus aureus ATCC 25922, and Klepsiella pneumoniae ATCC 13883) using the broth microdilution method . The alkaloids 1 – 16 , 25 – 27 , 31 , and 32 showed the best antibacterial activity against P. aeruginosa (MIC range 2–22 μM), while compounds 2 (MIC = 5 μM), 5 (MIC = 5 μM), 11 (MIC = 2 μM), and 15 (MIC = 2 μM) showed the best activity against E. faecalis (Table ).…”

Section: Resultsmentioning

confidence: 99%

“…The strains were obtained from the American Type Culture Collection (ATCC, Rockville, MD, USA), Centraalbureau voor Schimmelcultures (CBS, Holland), Ecole Nationale Vétérinaire d’Alfort (France), and Centre Pasteur of Yaounde (Cameroon). The MIC values were determined by the broth microdilution method as described . The tests were conducted for three independent replicates.…”

Section: Methodsmentioning

confidence: 99%

Melokhanines A–J, Bioactive Monoterpenoid Indole Alkaloids with Diverse Skeletons fromMelodinus khasianus

Cheng

Hou

et al. 2016

J. Nat. Prod.

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The new melokhanines A-J (1-10) and 22 known (11-32) alkaloids were isolated from the twigs and leaves of Melodinus khasianus. The new compounds and their absolute configurations were elucidated by extensive analysis of spectroscopic, X-ray diffraction, and computational data. Melokhanine A (1), composed of a hydroxyindolinone linked to an octahydrofuro[2,3-b]pyridine moiety, is an unprecedented monoterpenoid indole alkaloid. Melokhanines B-H (2-8) possess a new 6/5/5/6/6 pentacyclic indole alkaloid skeleton. Alkaloids 1-16, 25-27, 31, and 32 showed the best antibacterial activity against Pseudomonas aeruginosa (MIC range 2-22 μM). Among the seven dermatophytes tested, compound 1 showed significant inhibitory activity against Microsporum canis, M. ferrugineum, and Trichophyton ajelloi (MIC range 38-150 μM), i.e., half the efficacy of the positive control, griseofulvin.

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“…Chemical Components Summary of Cassava. 19,22,23,25,31,33,34,38,40,45,[47][48][49]53,88,89,93,[95][96][97][98] Phytochemical groups Components Plant part Extraction methods/solvent used References…”

Section: Phytochemistrymentioning

confidence: 99%

Cassava (Manihot esculenta Crantz): A Systematic Review for the Pharmacological Activities, Traditional Uses, Nutritional Values, and Phytochemistry

Mohidin,

Moshawih,

Hermansyah

et al. 2023

J Evid Based Complementary Altern Med

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Cassava ( Manihot esculenta Crantz) is considered one of the essential tuber crops, serving as a dietary staple food for various populations. This systematic review provides a comprehensive summary of the nutritional and therapeutic properties of cassava, which is an important dietary staple and traditional medicine. The review aims to evaluate and summarize the phytochemical components of cassava and their association with pharmacological activities, traditional uses, and nutritional importance in global food crises. To collect all relevant information, electronic databases; Cochrane Library, PubMed, Scopus, Web of Science, Google Scholar, and Preprint Platforms were searched for studies on cassava from inception until October 2022. A total of 1582 studies were screened, while only 34 were included in this review. The results of the review indicate that cassava has diverse pharmacological activities, including anti-bacterial, anti-cancer, anti-diabetic, anti-diarrheal, anti-inflammatory, hypocholesterolemic effects, and wound healing properties. However, more studies that aim to isolate the phytochemicals in cassava extracts and evaluate their pharmacological property are necessary to further validate their medical and nutritional values.

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Chemical Constituents from the Stems of Manihot esculenta

Cited by 6 publications

References 15 publications

Comparative analysis and characterization of the chloroplast genome of Krascheninnikovia ceratoides (Amarathaceae): a xerophytic semi-shrub exhibiting drought resistance and high-quality traits

Comparative analysis and characterization of the chloroplast genome of Krascheninnikovia ceratoides (Amarathaceae): a xerophytic semi-shrub exhibiting drought resistance and high-quality traits

Melokhanines A–J, Bioactive Monoterpenoid Indole Alkaloids with Diverse Skeletons fromMelodinus khasianus

Cassava (Manihot esculenta Crantz): A Systematic Review for the Pharmacological Activities, Traditional Uses, Nutritional Values, and Phytochemistry

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