Chemical constituents from<i>Sedum aizoon</i>and their hemostatic activity

Lin, Zongkai; Fang, Yingjuan; Huang, Anyu; Chen, Liyun; Suhua, Guo; Chen, Jianwei

doi:10.3109/13880209.2014.895019

Cited by 44 publications

(37 citation statements)

References 8 publications

(8 reference statements)

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“…Polyphenolic compounds derived from plants thanks to their antioxidant activity exhibit many medicinal properties such as anti-inflammatory [16], anticancer [17], antiatherogenic [18], antihemorrhagic [19], antibacterial [20], antifungal [21], antiviral [22], spasmolytic [23], diuretic [24], choleretic [25], and hepatoprotective [26] activity. Extracts from apple leaves are rich in phloridzin, which exhibit antidiabetic activity [27].…”

Section: Introductionmentioning

confidence: 99%

Analysis of Polyphenolic Compounds in Extracts from Leaves of SomeMalus domesticaCultivars: Antiradical and Antimicrobial Analysis of These Extracts

Sowa

Zgórka

Szykuła

et al. 2016

BioMed Research International

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In this study, methanol, ethyl acetate, water extracts, and precipitate were obtained from leaves of Malus domestica cultivars: Golden delicious, Jonagold, Elstar, Ligol, and Mutsu. Antiradical activity of these extracts was measured using the ABTS+∙ radical, and antimicrobial activity was measured with the disk-diffusion method. Phenolic compounds were measured with the colorimetric method and identified with high performance liquid chromatography (HPLC). The highest antiradical activity was observed for the Jonagold variety, and in particular strong activity was noted for ethyl acetate extracts. Antimicrobial activity was observed against strains of Staphylococcus aureus, Enterococcus faecalis, and the fungus Candida glabrata. Particularly susceptible to the extracts activity appeared to be Staphylococcus aureus, but the growth of Candida glabrata was inhibited in the presence of ethyl acetate extracts. With the HPLC method we identified a high amount of phloridzin (above 500 mg per g of ethyl acetate extracts), lower amounts of hyperoside, isoquercitrin, and quercitrin, and traces of p-hydroxybenzoic and chlorogenic acids. The contribution of phloridzin to antiradical activity of methanol and ethyl acetate extracts was very high (above 90%). In water extract the contribution of phloridzin was between 38.9 and 55.2%, chlorogenic acid 22.7 and 36.1%, and hyperoside 12.2 and 13.3%.

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Section: Introductionmentioning

confidence: 99%

Analysis of Polyphenolic Compounds in Extracts from Leaves of SomeMalus domesticaCultivars: Antiradical and Antimicrobial Analysis of These Extracts

Sowa

Zgórka

Szykuła

et al. 2016

BioMed Research International

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“…Other five known compounds were identified as aurantiamide acetate ( 2 ), 3‐formyl‐6‐methoxycarbazole ( 3 ), aralia cerebroside ( 4 ), uracil ( 5 ), thymine ( 6 ) by extensive 1D and 2D NMR spectroscopy according to the reported data in the literatures. In our present phytochemical study, six nitrogen‐containing organic compounds, including three alkaloids ( 1 – 3 ), two nucleic acid‐containing nitrogenous bases ( 5 and 6 ) and one cerebroside ( 4 ) were isolated from the aerial parts of Bupleurum chinense DC.…”

Section: Resultsmentioning

confidence: 99%

A New Alkaloid from the Aerial Parts of Bupleurum chinense DC.

Xiao

Liu

Sun

et al. 2020

Chemistry & Biodiversity

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A new isoalloxazine alkaloid, named bupleurine A (1), along with five known compounds (2–6), were isolated from the aerial parts of Bupleurum chinense DC. The structure elucidation of the new alkaloid (1) was employed by combining NMR and HR‐MS data with comparison of reference in the literature. Five known compounds (2–6) were isolated from Bupleurum genus for the first time. Additionally, their antiproliferative activities on HeLa cells were evaluated by MTT assay and IC50 of compounds 1 and 4–6 were below 10 μm after treatment for 24 h.

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“…Meanwhile, this herb could also reduce the risk of chronic and cardiovascular diseases and effectively improve the blood pressure and cholesterol levels in the human body (Xu et al., 2015). The health beneficial properties of Sedum aizoon L. have been confirmed to be attributed primarily to phytochemicals, such as flavonoids, phenolic acids, polysaccharose, and alkaloids according to the previous studies (Lin et al., 2014; Liu et al., 2012; Xu et al., 2019). For instance, it has been reported that Sedum aizoon L. contained high levels of myricetrin, myricetin, quercitrin, quercetin, gallic acid, and kaempferol (Lin et al., 2014; Liu et al., 2012; Xu et al., 2019; Yan, 2013).…”

Section: Introductionmentioning

confidence: 82%

“…This flowering plant is characterized by light green leaves on the thick stems and blooms in the summer period with yellow flowers. Sedum aizoon L. has been generally consumed as a folk medicine in China and mainly planted in the province of Fujian, Jiangsu, Zhejiang, and Henan in China (Lin et al., 2014). Sedum aizoon L. is also known as “tusanqi” in China and it is served as a traditional medicine with multiple health beneficial features (Li et al., 2011; Liu, Ma, Wu, Lai, & Zhang, 2012).…”

Section: Introductionmentioning

confidence: 99%

Effect of different drying methods on phenolic compounds and antioxidant capacity in different fractions of Sedum aizoon L.

Gong

Qiu

Weng

et al. 2020

J Food Process Preserv

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This study investigated the effect of different drying treatments on phenolic composition and antioxidant activity in different fractions of Sedum aizoon L. Results showed that the highest flavonoids content was found in the flower fraction, which also possessed the strongest antioxidant capacity confirmed by DPPH, ABTS, and FRAP assays. Four phenolic compounds were detected in Sedum aizoon L. Myricetrin and quercitrin were the dominant phenolic compounds in all the fractions, whereas the stem fraction did not contain myricetin. Among the drying treatments, each freeze‐dried fraction exhibited the highest antioxidant activities and total flavonoids. The oven‐ and sun‐drying treatments resulted in a loss on the total flavonoids and antioxidant properties. A positive correlation of antioxidant activities in Sedum aizoon L. was found with myricetrin, quercitrin and total flavonoids. This study could provide useful information on the nutritional quality improvement of Sedum aizoon L. through different drying methods. Practical applications Sedum aizoon L. has been generally consumed as a folk medicine with multiple health beneficial features in China. The health beneficial properties of Sedum aizoon L. have been confirmed to be attributed primarily to phytochemicals, such as flavonoids and phenolic acids. The major consumption parts in Sedum aizoon L. in China include stems, leaves, and flowers. Normally, a drying process has been applied to Sedum aizoon L. for a longer shelf life need. The present study investigated the distribution of gallic acid, myricetrin, quercitrin, and myricetin in different parts of Sedum aizoon L., and further assessed if different drying methods could alter the level of these phenolic compounds and antioxidant properties in these parts of Sedum aizoon L. This study provides direct knowledge on the accumulation of phenolic compounds in different parts of Sedum aizoon L., and further bring a practical method on the best preserve functional compounds in Sedum aizoon L.

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Chemical constituents fromSedum aizoonand their hemostatic activity

Abstract: SA produced hemostatic activity possibly related to the presence of gallic acid, vallinic acid, and luteolin, which may be potent candidates of hemostatic drug.

Cited by 44 publications

References 8 publications

Analysis of Polyphenolic Compounds in Extracts from Leaves of SomeMalus domesticaCultivars: Antiradical and Antimicrobial Analysis of These Extracts

Analysis of Polyphenolic Compounds in Extracts from Leaves of SomeMalus domesticaCultivars: Antiradical and Antimicrobial Analysis of These Extracts

A New Alkaloid from the Aerial Parts of Bupleurum chinense DC.

Effect of different drying methods on phenolic compounds and antioxidant capacity in different fractions of Sedum aizoon L.

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