Chemical Constituents from Alseodaphne andersonii

Abstract

Five new compounds, including four C(17) gamma-lactones, dihydroisoobtusilactone (1), dihydroobtusilactone (2), 3-epilitsenolide D(2) (3), and 3-epilitsenolide D(1) (4), and one furanone alseodafuranone (5), were isolated from the root and stem of Alseodaphne andersonii. Their structures were elucidated mainly by spectral analysis (NMR and MS) and partially by chemical correlation.

Revision of the Absolute Configuration of Plumericin and Isoplumericin fromPlumeria rubra

“…4). The calculated CD spectrum exhibited a negative couplet at 219 nm, again in accordance with the literature data (226 nm; Table 1) [33]. The results of these two calculations demonstrate the accuracy of the applied calculations and also confirmed the absolute configuration of the loganin derivative 5, which is homochiral with the corresponding substructure of the more-condensed plumericins (1 and 2; hitherto accepted configuration) regarding the stereogenic centers C(1), C(4a), and C(7a) of 5.…”

“…In order to probe the method on plumericin (1), and to test whether the program would give reliable results for these complicated chromophores, we calculated the CD spectra of the two plumericin fragments 5 and 6, which contain a,b-unsaturated ester and g-lactone moieties, respectively. These fragments were selected because the CD data of the loganin derivative 5 [32], and that of 3-epilitsenolide D 2 (7) [33], are available in the literature.…”

The Effect of the Aerial Part of Lindera akoensis on Lipopolysaccharides (LPS)-Induced Nitric Oxide Production in RAW264.7 Cells

“…Extensive normal phase Si gel column chromatographic purification of the EtOAc-soluble fraction afforded four new compounds, 3α-(( E )-Dodec-1-enyl)-4β-hydroxy-5β-methyldihydrofuran-2-one ( 1 ), linderinol ( 6 ), 4′- O -methylkaempferol 3- O -α- l -(4″- E - p -coumaroyl)rhamnoside ( 11 ), kaempferol 3- O -α- l -(4″- Z - p- coumaroyl) rhamnoside ( 12 ), as well as eleven known compounds, 3-epilistenolide D 1 ( 2 ) [17], 3-epilistenolide D 2 ( 3 ) [17], (3 Z ,4α,5β)-3-(dodec-11-ynylidene)-4-hydroxy-5-methylbutanolide ( 4 ) [18], (3 E ,4β,5β)-3-(dodec-11-ynylidene)-4-hydroxy-5-methylbutanolide ( 5 ) [19], matairesinol ( 7 ) [20], syringaresinol ( 8 ) [21], (+)-pinoresinol ( 9 ) [22], salicifoliol ( 10 ) [23], 4″- p -coumaroylafzelin ( 13 ) [24], catechin ( 14 ) [25] and epicatechin ( 15 ) [25] (Figure 1). …”

The natural compounds atraric acid and N-butylbenzene-sulfonamide as antagonists of the human androgen receptor and inhibitors of prostate cancer cell growth

“…1). AA occurs in lichens and has been isolated from higher plants like Newbouldia laevis (Gormann et al, 2003), Alseodaphne andersonii (Lee et al, 2001), Acer nikense (Nagumo et al, 1996) and Frullania brasiliensis (Bardón et al, 2002). Previously it was found as a degradation product of various natural depsides.…”