Chemical constituents and pharmacological effects of genus Engelhardia

Pang, Yanmei; Qi, Shihua; Fang, Zhou; Hua, Jie; Hou, Wenting

doi:10.1016/j.chmed.2018.01.007

Cited by 7 publications

(12 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The main secondary metabolites isolated from this species are steroidal saponins, isoflavones, and polysaccharides. [68,69]…”

Section: Discussionmentioning

confidence: 99%

The Potential of Huangqi Decoction for Treating Diabetic Kidney Disease

Chen,

Liu,

Cao

2024

Integr Med Nephrol Androl

View full text Add to dashboard Cite

Diabetic kidney disease (DKD) is a prevalent complication of diabetes mellitus that primarily affects the kidney microvasculature. According to the Traditional Chinese Medicine (TCM) theory, early-stage DKD is characterized by deficiencies in essence and Qi and is often accompanied by spleen and kidney deficiencies. Huangqi decoction (HQD), a classic Chinese herbal formula with historical use in treating thirst-related ailments, is described in Shiyin Yang's Renzhai Zhizhi Fang Lun. This review aimed to investigate the potential molecular mechanisms, pharmacological effects, and key targets of HQD to establish a theoretical and scientific foundation for further research and clinical applications. The bioactive compounds and targets of HQD were retrieved from the Traditional Chinese Medicine Systems Pharmacology (TCMSP) database, and compound-target and protein-protein interaction networks were constructed using Cytoscape and BisoGent, respectively. A total of 172 bioactive compounds were identified in HQD. Gene Ontology (GO) enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses of the hub targets indicated associations between diverse biological processes, cellular components, and molecular functions. These findings signify a promising avenue for the development of evidence-based treatments for DKD by leveraging the potential of TCM to enhance patient outcomes.

show abstract

“…The main secondary metabolites isolated from this species are steroidal saponins, isoflavones, and polysaccharides. [68,69]…”

Section: Discussionmentioning

confidence: 99%

The Potential of Huangqi Decoction for Treating Diabetic Kidney Disease

Chen,

Liu,

Cao

2024

Integr Med Nephrol Androl

View full text Add to dashboard Cite

show abstract

“…Atractylodes can enhance the function of red blood cells, which also has the effect of antioxidant and anti-inflammatory. Moreover, Atractylodes can regulate immunity, which can enhance the body's non-specific immunity [ [51] , [52] , [53] ]. Achyranthes-Huai has an active effect on T cells, which has the effect of regulating immunity and anti-inflammatory [ 48 , 54 ].…”

Section: Discussionmentioning

confidence: 99%

Efficacy and safety of Simiao decoction in the treatment of cervical HPV infection: A systematic review and meta-analysis of randomized clinical trials

Qiu,

Chen,

Wang

et al. 2023

Heliyon

View full text Add to dashboard Cite

“…experiencing tropical warm humid climate (Fig. 8) (Meng et al, 2015;Pang et al, 2018;Song et al, 2019). We assume that the disappearance of Palaeocarya sect.…”

Section: Monocostatamentioning

confidence: 99%

“…Engelhardia, a semi-evergreen deciduous tree, grows in mixed tropical forests at an altitude of about 2000 m above sea level (Pang et al, 2018). This genus consists of five species (Song et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

First fossil evidence of Palaeocarya (Engelhardioideae: Juglandaceae) from India and its biogeographical implications

Hazra

Kumar

et al. 2021

J of Sytematics Evolution

View full text Add to dashboard Cite

Even though presently indigenous to eastern Himalaya in India, no Engelhardioideae have been reported from the Cenozoic sediments of India till date. Here, we report the first Indian occurrence of a characteristic engelhardioid winged samaroid fruit having a tri-lobed wing (oblong-ovate median lobe and two lateral lobes) and a globose nut from the latest Neogene (Pliocene: Rajdanda Formation) sediments of Chotanagpur Plateau, eastern India. This is the first fossil evidence of relict family Juglandaceae from the Indian Cenozoic. We determine its taxonomic position on the basis of detailed macromorphological comparison with similar extant and fossil specimens and discuss its palaeoclimatic significance in terms of the present-day distribution of modern analogous species. We assign this Pliocene winged fruit specimen to the morphogenus Palaeocarya sect. Monocosta Manchester and describe it as a new species, namely Palaeocarya indica Hazra, Hazra M & Khan sp. nov. Palaeocarya sect. Monocosta has rich fossil records from the Cenozoic sediments of Europe, North America, and eastern Asia (China, Korea), but the modern analog, Engelhardia, is presently native only to India and neighboring Southeast Asia. We discuss the possible causes of disappearance of Engelhardia from the present-day vegetation of Chotanagpur Plateau. Its disappearance may be related to the gradual intensification of monsoonal rainfall seasonality since the Pliocene. Here, we also review in detail the biogeographic history of Palaeocarya sect. Monocosta and suggest its possible migration routes.

show abstract

Chemical constituents and pharmacological effects of genus Engelhardia

Cited by 7 publications

References 34 publications

The Potential of Huangqi Decoction for Treating Diabetic Kidney Disease

The Potential of Huangqi Decoction for Treating Diabetic Kidney Disease

Efficacy and safety of Simiao decoction in the treatment of cervical HPV infection: A systematic review and meta-analysis of randomized clinical trials

First fossil evidence of Palaeocarya (Engelhardioideae: Juglandaceae) from India and its biogeographical implications

Contact Info

Product

Resources

About