Chemical Constituents and Bioactivities of Plants of Chloranthaceae

Terpenoids from Chloranthus elatior

“…The above NMR spectroscopic data suggested that 1 was an eudesmane-type sesquiterpenoid lactone, which has been widely discovered from this genus. [4][5][6][7][8] Comparison of NMR data of 1 with those of neolitacumone B (7) 15 indicated that 1 differed from 7 by the presence of a methyl (δ H 0.93, d, J = 6.0 Hz and δ C 19.8) and a methine (δ H 1.48, m and δ C 31.6) instead of one terminal double bond in 7, which was reasonable to assume that 1 is the 4,15-dihydrogenation derivative of 7. In the HMBC spectrum (Figure 1), the correlations of Me-15 (δ H 0.93) with C-3 (δ C 33.8), C-4 (δ C 31.6), and C-5 (δ C 50.6) were observed, which confirmed the above assumption.…”

“…3 Previous work on this genus indicated that sesquiterpenoids and disesquiterpenoids were their major secondary metabolites. [4][5][6][7][8][9][10][11] Disesquiterpenoids were reported to exhibit inhibition of cell adhesion molecule expression, antifungal activity, anti-HIV-1 activity, tumor growth inhibitory activity, potent and selective inhibition on the delayed rectifier (I k ）K + current. 10,11 The tyrosinase inhibitory activity and cytotoxicity of sesquiterpenoids also have been reported.…”

Two Flavonoid Dimers from Sarcandra hainanensis (PEI) SWAMY et BAILEY

“…In addition to two new compounds, 3 known compounds (3)(4)(5) were also isolated from the title plant for the first time. Structures of those compounds were identified as isofraxidin (3), 7-hydroxy-5,8-dimethoxyflavanone (4) and pinostrobin (5) by comparison of their spectroscopic data with those reported in literature.…”

“…3 based on its NOESY spectrum and MM 2 calculation. Different stereochemistry of 2 from 1 mainly reflected on the NOEs of H-2 (C), H-4 (C) and 4Ј-OCH 3 …”

Two New Flavan-Flavanones from Sarcandra hainanensis

“…2) Previous chemical studies of Sarcandra species have led to the isolation of chalcones and sesquiterpenes. [3][4][5][6] As a continuous study on the chemical constituents of S. hainanensis, 6,7) two new flavan-flavanones (1, 2, Fig. 1) together with 6 known compounds (3)(4)(5)(6)(7)(8) were isolated.…”