Chemical Compounds from Patrinia Villosa (Thunb.) Juss

Abstract

The objective of this research is to isolate and identify the bioactive components from Patrinia villosa (Thunb.) Juss. 70% EtOH extract of P. villosa was firstly partitioned with light petroleum, dichloromethane and n-BuOH, and then subjected to normal-phase silica, ODS silica gel column chromatography and semi-preparative HPLC chromatography. NMR method was adopted in this research to elucidate the chemical structures of the compounds. Four known compounds were isolated from P. villosa, and identified as Patrinalloside (1), Patrinoside-aglycone-11-O-2'-deoxy-β-D-glucopyranoside (2), Patrinoside-a-glucone (3), Sweroside (4) by comparison of their spectral data with the reported data. This is the first time that the compounds mentioned above were isolated from P. villosa.