Chemical compounds, antioxidant and scolicidal potencies of Thymus fontanesii essential oil

Selles, Sidi Mohammed Ammar; Belhamiti, Belkacem Tahar; Kouidri, Mokhtaria; Ait Amrane, Amar; Kadari, Yamina; Kaddour, Zohra; Kabrit, Souad

doi:10.1016/j.exppara.2024.108699

Experimental Parasitology

2024

DOI: 10.1016/j.exppara.2024.108699

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Chemical compounds, antioxidant and scolicidal potencies of Thymus fontanesii essential oil

Sidi Mohammed Ammar Selles,

Belkacem Tahar Belhamiti,

Mokhtaria Kouidri

et al.

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2024

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Genotoxic and antiproliferative effect of Alpinia zerumbet (Zingiberaceae) essential oil in Allium cepa biotest

Sousa,

Silva,

Orlanda

2024

CeN

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The species Alpinia zerumbet popularly known as colony is quite abundant in northeastern Brazil and is widely used for medicinal purposes, due to its hypotensive and cardiovascular effect, without, however, due scientific evidence. Therefore, the objective of this study was to evaluate the genotoxic and antiproliferative effect of A. zerumbet essential oil, in test systems with Allium cepa. The chemical composition of the essential oil was determined by gas chromatography coupled with mass spectrometry (GC-MS). The antiproliferative and genotoxic effect was tested in seven treatments with three replications, and five concentrations of essential oil (0.01 to 1.0%) using onion bulbs. Two roots were analyzed from each bulb, with a count of 500 cells per slide/root, totaling 3,000 cells per treatment. The results showed that the main chemical constituents of the essential oil were 1.8 cineole (60.50%) and terpinen-4-ol (23.80%). In the assays with A. cepa, both the mitotic index (MI) and the cellular alteration percentages differed significantly in relation to the control, through the appearance of chromosomal and nuclear aberrations at the concentrations tested, revealing possible harmful effects to human health.

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Genotoxic and antiproliferative effect of Alpinia zerumbet (Zingiberaceae) essential oil in Allium cepa biotest

Sousa,

Silva,

Orlanda

2024

CeN

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show abstract

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Chemical compounds, antioxidant and scolicidal potencies of Thymus fontanesii essential oil

Cited by 1 publication

References 45 publications

Genotoxic and antiproliferative effect of Alpinia zerumbet (Zingiberaceae) essential oil in Allium cepa biotest

Genotoxic and antiproliferative effect of Alpinia zerumbet (Zingiberaceae) essential oil in Allium cepa biotest

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