Chemical Compositions and Biological Activities of Scutellaria Genus Essential Oils (Lamiaceae)

Abstract

Context: Essential oils are secondary metabolites with versatile organic structures that, due to their compounds, have useful medicinal properties. There are about 250 species of the genus of Scutellaria perennial flowering plants from the Lamiaceae family. Its application for the treatment of allergy, inflammatory, hyperlipidemia, arteriosclerosis, hypertension, and hepatitis has a long history. Evidence Acquisition: Various studies on the chemical compounds of the Scutellaria genus have identified several ‎compounds, especially essentials oils. The current review is based on the evidence found in Chemical Abstract, Science Direct, Scopus, PubMed, Web of Knowledge, and Google Scholar databases. Results: Many studies on the chemical components of essential oils from the Scutellaria genus have identified several compounds. We summarized the chemical compositions and biological activities of Scutellaria essential oils. Hexadecanoic acid, germacrene D, β-caryophyllene, linalool, β-farnesene, and eugenol are the main compounds in essential oils of this genus. Despite many reports about essential oils of Scutellaria species (more than 38), a large number of species have not been studied yet. Therefore, several studies should be conducted on the chemical compounds and biological activities of unstudied Scutellaria essential oils. Conclusions: This review has summarized reports on the chemistry and biological activities of Scutellaria essential oils,‎ such as antioxidant, antimicrobial, antifeedant, phytotoxic, and acaricidal toxicities, based on the recent literature.

GC-MS Analysis and Biomedical Therapy of Oil from n-Hexane Fraction of Scutellaria edelbergii Rech. f.: In Vitro, In Vivo, and In Silico Approach

“…Our data also agree with the reported data of Yu et al [43], where the oils of S. barbata were tested against different bacterial strains. Gram-positive strains are more susceptible to oil compared to Gram-negative bacterial strains, which agrees with the findings of Kasaian et al [4].…”

“…The study will update, and validate the aroma therapeutic importance, and add a further implication to the biopotency. Plant species from the same genus Scutellaria have been previously investigated for the oil composition and their therapeutic importance where it has been concluded that the Scutellaria genus plays a key role in curing various ailments, however, this still requires further scientific authentication [4].…”

“…To evaluate the significance of the tested samples, experimental animals' paw diameter was measured and noted after 1, 2, and 3 h, respectively. The anti-inflammatory % inhibition was calculated as per Equation (4).…”

“…Plants extracted oils consist of versatile chemical constituents and are well known for their diverse medicinal significance, originating from plants using classical and advanced approaches [4]. Numerous techniques were adopted for the extraction of oils including hydro-distillation, steam-distillation, micro-wave, and organic solvent extraction [5].…”

Scutellaria petiolata Hemsl. ex Lace & Prain (Lamiaceae).: A New Insight in Biomedical Therapies

“…In addition to that five terpenoids ( 9, 10, 11, 13, and 14 ) were observed in PIM in the most active extract previously reported from S. drummondii , S. rubicunda , and S. barbata [ 62 , 66 , 67 ] having the therapeutic significance to act as an antioxidant, antibacterial, and anti-inflammatory agent [ 32 , 68 , 69 ]. The SPM contains three alkaloids two compounds ( 1 and 3 ) were noticed in NIM and one compound ( 5 ) was observed in PIM previously reported from S. flavescens [ 70 ] and is well-known for its antioxidant, antimicrobial, anti-allergenic, analgesic, and anti-inflammatory [ 71 , 72 , 73 ], while one compound 19 observed in PIM was representing the phenolic group which was previously reported from S. baicalensis [ 74 ] and can inhibit microbial growth [ 75 ].…”