Chemical composition of the rhizomes of the Rhodiola rosea by the HPLC method

Dubichev, A. G.; Куркин, В. А.; Zapesochnaya, G. G.; Vorontsov, E. D.

doi:10.1007/bf00629750

Cited by 9 publications

(13 citation statements)

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“…rosea cultivated in the Moscow, Leningrad, and Samara regions [5,36,38] contains practically the same set of substances which is characteristic of wildgrowing plants [5,59,[65][66][67]; the relative contents of the major biologically active components was also virtually iden- tical in the materials of the two types. There was a difference in the absolute content of these components, because cultivated plants contain a smaller amount of extracted substances.…”

Section: Standardization Methodsmentioning

confidence: 99%

“…rosea, developed at the Institute of Medicinal and Aromatic Plants (VILAR Corporation), are based on the results obtained using TLC, HPLC, and spectrophotometric techniques [40,62,[65][66][67][68]. The methods employ SSS "Rosavin" prepared using a special technology developed at the VILAR Corporation, included in a project of the corresponding Pharmacopoeial Issue.…”

Section: Standardization Methodsmentioning

confidence: 99%

“…The pharmacological data on the activity of new individual substances isolated from Rh. rosea [67][68][69]71], in combination with the results of chemical investigations, led to the development of a method providing maximum extraction and preservation in natural form of all biologically active components of this valuable plant material [73].…”

Section: Standardization Methodsmentioning

confidence: 99%

“…rosea was studied using the HPLC procedure developed for rosavin determination [67]. It was found that the content of rosavin drops sharply already in the stage of raw material conversion into pulp at room temperature, although the process markedly accelerates at 40~ Apparently, the most active enzyme in the glycosylating system of Rh.…”

Section: Chemical Compositionmentioning

confidence: 99%

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Traditional and biotechnological aspects of obtaining medicinal preparations fromRhodiola Rosea L. (A review)

1999

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By now, there are about 300 medicinal plants successfully used in medical practice. Moreover, recent years showed a steady tendency for extending this class.Obtaining phytopreparations always involves extraction of the biologically active substances, followed by their separation and purification using various technological methods. One of the main negative factors, introducing instability in the manufacture of phytopreparations, is an irregular character of the supply of raw materials for their production. The reasons include, in particular, a sharp decrease in the natural stock of both wild-growing and cultivated medicinal plants.In connection with this, both the search for new medicinal plants and work on creation of a reliable stock of pharmacopoeial plants are of considerable practical value. Besides the traditional work on large-scale cultivation of medicinal plants, a highly promising direction is the biotechnological production of raw plant materials and related preparations.Biotechnology, which means carrying out technological processes with the aid of biological systems, has been rapidly developing in the past years and is recognized as a priority direction in the future scientific progress [ 1 -8].An important field of biotechnology is the growth of plant cells (or medicinal plant tissue cultures), in which the main difficulties are related to development of the necessary commercial equipment. This field is most extensively developed in Japan, where large-scale cultivation of plant cells was successfully realized many years ago (a 20-m 3 biomass reported in 1976) [1].From the standpoint of the commercial growth of cultures, the most efficient technology is that based on bulk cultivation (suspension cell culture). This method reduces the process time and minimizes manual operations as compared

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Section: Standardization Methodsmentioning

confidence: 99%

Section: Standardization Methodsmentioning

confidence: 99%

Section: Standardization Methodsmentioning

confidence: 99%

Section: Chemical Compositionmentioning

confidence: 99%

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Traditional and biotechnological aspects of obtaining medicinal preparations fromRhodiola Rosea L. (A review)

1999

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“…Processes of separation and purification of aromatic acids are extensively studied both by the conventional methods of liquid column chromatography [1][2][3], ion-exchange chromatography [4,5], and high-performance liquid chromatography [6][7][8][9], and by the non-classical affinity chromatography techniques using affinity-type adsorbents (ATA) [10][11][12]. For example, Meyerhaff et al [10] immobilized tetraphenylporphyrin and its complexes with metal ions on aminopropyl silica gel and successfully used this ATA for the separation of aromatic acids in various chromatographic regimes (anion exchange, etc.).…”

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confidence: 99%

Polymeric affinity-type adsorbents in the study of physiologically active substances. Part XI. Effect of structure parameters of hydrazono(azomethino)-containing adsorbents on the separation of aromatic acids

1997

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Herbal medicines in the treatment of psychiatric disorders: 10‐year updated review

Sarris

2018

Phytotherapy Research

136

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This paper provides a 10-year update of the 2007 systematic review of herbal medicines studied in a broad range of psychiatric disorders, including depression, anxiety, obsessive-compulsive, seasonal affective, bipolar, psychotic, phobic, somatoform, and attention-deficit hyperactivity disorders. Ovid Medline, PubMed, and the Cochrane Library were searched for herbal medicines with both pharmacological and clinical evidence of psychotropic activity. This updated review now covers clinical trial evidence for 24 herbal medicines in 11 psychiatric disorders. High-quality evidence was found to exist for the use of Piper methysticum (Kava), Passiflora spp. (passionflower) and Galphimia glauca (galphimia) for anxiety disorders; and Hypericum perforatum (St John's wort) and Crocus sativus (saffron) for major depressive disorder. Other encouraging herbal medicines with preliminary evidence include Curcuma longa (turmeric) in depression, Withania somnifera (ashwagandha) in affective disorders, and Ginkgo biloba (ginkgo) as an adjunctive treatment in Schizophrenia. Although depression and anxiety are commonly researched, many other mental disorders still require further prospective investigation. Although the previous review suggested increasing the adjunctive study of select herbal medicines with pharmaceuticals, this was still only found to sparingly occur in research designs. Aside from this, future focus should involve the incorporation of more biomarker analysis, in particular pharmacogenomics, to determine genetic factors moderating response to herbal medicines.

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Chemical composition of the rhizomes of the Rhodiola rosea by the HPLC method

Cited by 9 publications

References 0 publications

Traditional and biotechnological aspects of obtaining medicinal preparations fromRhodiola Rosea L. (A review)

Traditional and biotechnological aspects of obtaining medicinal preparations fromRhodiola Rosea L. (A review)

Polymeric affinity-type adsorbents in the study of physiologically active substances. Part XI. Effect of structure parameters of hydrazono(azomethino)-containing adsorbents on the separation of aromatic acids

Herbal medicines in the treatment of psychiatric disorders: 10‐year updated review

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