Chemical composition, antioxidant, antimicrobial and antifungal activity of Moroccan Cistus Creticus leaves

Lahcen, S Ait; Hattabi, Latifa El; Benkaddour, R.; Chahboun, N.; Ghanmi, Mohamed; Satrani, Badr; Tabyaoui, Mohamed; Zarrouk, A.

doi:10.1016/j.cdc.2020.100346

Cited by 33 publications

(29 citation statements)

References 31 publications

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“…Since ancient times, Cistaceae have been used in ethnomedicine due to their pharmacological potential against a broad range of disorders, including various skin diseases, diarrhea, ulcers, dysentery, catarrh, menstruation difficulties, and gout due to a number of natural pharmacological compounds they consist of [ 2 , 3 , 4 ]. According to ethno-pharmacology, the Cistus species has been used due to its antimicrobial, antiproliferative, anticancer, antiviral, antioxidant, anti-inflammatory, antiulcerogenic, antidiarrheal, and antispasmodic activity [ 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 ]. It is also known that some Cistus species have been used in human and animal diets, such as goats, lamb and beef [ 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 ].…”

Section: Introductionmentioning

confidence: 99%

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UPLC-MS/MS Phytochemical Analysis of Two Croatian Cistus Species and Their Biological Activity

Carev

Maravić

Ilić

et al. 2020

Life

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Aqueous extracts of two Cistus species wild growing in Croatia—Cistus creticus (CC) and Cistus salviifolius (CS)—have been assessed with UPLC-MS/MS, showing 43 different phytochemicals, with flavonol glycosides: myricetin-3-hexoside and myricetin-rhamnoside, predominate ones in CC and myricetin-3-hexoside in CS. Antioxidant potential tested with the FRAP method showed no difference between CS and CC aqueous extracts, while higher phenolic content of CC comparing to CS, determined with a Folin–Cicolateu reagent correlated to its higher antioxidant capacity observed by the DPPH method. Both extracts were assessed for antimicrobial activity, using disc-diffusion and broth microdilution assays, targeting the opportunistic pathogens, associated with food poisoning, urinary, respiratory tract, blood stream and wound infections in humans. Antimicrobial assays revealed that fungi were in general more sensitive to both Cistus aqueous extracts, comparing to the bacteria where two extracts showed very similar activity. The most potent activity was observed against A. baumannii for both extracts. The extracts were tested on human lung cancer (A549) cell line using the MTT assay, showing very similar antiproliferative activity. After 72 h treatment with CC and CS aqueous extracts in concentration of 0.5 g/L, the viability of the cells were 37% and 50% respectively, compared to non-treated cells.

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Section: Introductionmentioning

confidence: 99%

“…Phytochemical profile of different Cistus species aqueous extracts reveals their polyphenolic profile, having flavonoids, phenolic acids, and ellagitanins as their main constituents [ 2 , 3 , 6 , 8 , 10 , 15 , 23 , 26 , 31 , 32 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 ].…”

Section: Introductionmentioning

confidence: 99%

UPLC-MS/MS Phytochemical Analysis of Two Croatian Cistus Species and Their Biological Activity

Carev

Maravić

Ilić

et al. 2020

Life

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“…Familya Dünya genelinde dokuz cins ve yaklaşık 200-250 kadar bitki türü ihtiva etmekle birlikte; Helianthemum, Halimium, Fumara, Tuberaria ve Cistus cinsleri en yaygın olanlarıdır. [17][18][19] Önemli cinslerinden biri Cistus (laden)' dur, laden cinsine ait bitki türleri Güney Avrupa ile Kuzey Afrika orijinli olup, Akdeniz iklim kuşağında taşlı ve kiremitli açık alanlarda yayılış gösterirler. Çok yıllık veya çalımsı yapıda olan Laden türleri, her dem yeşil veya kısmen yeşil olan bitki türleridir.…”

Section: Coğrafik Dağılımı Ve Botanik öZellikleriunclassified

Türkiye’nin Virüs Savar Bitkisi Laden (Cistus spp.) Türleri: Geleneksel Kullanımları, Biyoaktif Kimyasal Bileşenleri ve Farmakolojik Aktiviteleri

Şekeroğlu¹,

Gezici²

2021

Mersin Üniversitesi Tıp Fakültesi Lokman Hekim Tıp Tarihi Ve Folklorik Tıp Dergisi

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Cistaceae familyasından olan Cistus (Laden) türleri; çok yıllık, çalı formunda, beyaz veya pembe çiçekli, genellikle Orta Doğu Akdeniz (Fransa ve İber Yarımadası hariç), Kuzey Afrika ve Batı Asya'da yayılım gösteren bitki türleridir. C. creticus L. (sinonim Cistus x incanus subsp. creticus (L.) Hetwood), C. salviifolius L., C. parviflorus Lam., C. monspeliensis L. ve C. laurifolius L. türleri Türkiye florasında doğal olarak yetişmekte olan, ekonomik ve endüstriyel öneme sahip laden taksonlarıdır. Bu bitkiler; halk arasında 'laden', 'laden otu', 'kaya gülü', 'pamukla', 'pamukluk', 'pamuk otu', 'davşanotu', 'karağan' ve 'tavşançalısı' olarak bilinmektedir. Laden türlerinin yaprakları, çiçekleri, tohumları rezin ve uçucu yağları; Anadolu Halk Hekimliğinde, infüzyon halinde kabızlık giderici, uyarıcı, balgam söktürücü, mide ve romatizmal hastalıkların tedavisinde, ayrıca mikroorganizma enfeksiyonlarına karşı koruyucu ve tedavi edici olarak yüzyıllardır geleneksel olarak kullanılmaktadır. Cistus türleri ihtiva ettikleri quercetin, myricetin, kaempferol, kaempferol-3-metil eter, apigenin, luteolin, aesculin, flavan-3-ol ve proantosiyanidin gibi oldukça farklı fitokimyasal içeriğe sahip olup, içerdiği bu doğal bileşikler sayesinde tıp alanında kullanımlarına yönelik antiviral, antimikrobiyal, antifungal, antioksidan, antienflamatuvar, antispazmodik ve antidiyabetik özelliklere sahip olduğunu rapor eden birçok bilimsel çalışma bulunmaktadır. Bu derlemede; ülkemizin en önemli virüs savar bitkilerinden olan Cistus türlerinin Anadolu geleneksel halk hekimliğindeki kullanımlarının yanı sıra; fitokimyasal bileşimleri, farmakokinetikleri, farmakolojik ve biyolojik aktiviteleri bilimsel veriler ışığında kapsamlı olarak sunulmuştur.

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“…The genus Cistus includes species of medicinal plants with various biological properties 9,[33][34][35][36] . The therapeutic properties of the species Cistus monspeliensis have been demonstrated in vitro; they are due to the presence of active compounds such as polyphenols 33,37,38 .…”

Section: %mentioning

confidence: 99%

“…Indeed, the ability of these inhibitors is generally attributed to the presence of secondary metabolites (polyphenols, alkaloids, saponins, etc.) having antioxidant power, readily available and renewable 8,9 . Currently, natural inhibitors are a topic of research in development based on the number of publications coming out each year [10][11][12][13][14] .…”

Section: Introductionmentioning

confidence: 99%

Cistus monspeliensis extract as antioxidant and corrosion inhibitor of ordinary steel in 1 M hydrochloric acid medium

Haida¹,

Bakkouche²,

Ouakki³

et al. 2020

Mediterr.J.Chem.,

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The aim of this study is the valorization of the Cistus monspeliensis plant, native to North of Morocco, as antioxidant and corrosion inhibitor. Firstly, the plant is extracted by maceration in a mixture of water/acetone solvents. Phytochemical tests are carried out on the extract obtained. The antioxidant power of Cistus monspeliensis extract is evaluated by two methods: the test of reduction of the free radical DPPH∙ (1,1-diphenyl-2-picryl hydrazyl) and that of Ferric reducing antioxidant power (FRAP). The electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization are used to study the anticorrosion effect of Cistus monspeliensis extract. The results showed that the extract, 27.6% yield, contains phenolic compounds in the form of flavonoids, hydrolysable and condensed tannins, saponins, reducing sugars and glycosides. This extract has an antioxidant capacity similar to that of ascorbic acid with an inhibition concentration of 0.077 mg/mL 0.102 mg/mL for DPPH and FRAP test, respectively. Tafel plots show that the extract is an excellent cathodic inhibitor. The maximum inhibition efficiency of 92 % was obtained with 0.25 g/L of the inhibitor at 298 k. The impedance plot is characterized by a single capacitive loop attributed to the charge transfer process. The results also showed that the inhibitor acts on the surface of the metal principally by adsorption, leading to the formation of a protective film limiting the corrosion of ordinary steel.

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Chemical composition, antioxidant, antimicrobial and antifungal activity of Moroccan Cistus Creticus leaves

Cited by 33 publications

References 31 publications

UPLC-MS/MS Phytochemical Analysis of Two Croatian Cistus Species and Their Biological Activity

UPLC-MS/MS Phytochemical Analysis of Two Croatian Cistus Species and Their Biological Activity

Türkiye’nin Virüs Savar Bitkisi Laden (Cistus spp.) Türleri: Geleneksel Kullanımları, Biyoaktif Kimyasal Bileşenleri ve Farmakolojik Aktiviteleri

Cistus monspeliensis extract as antioxidant and corrosion inhibitor of ordinary steel in 1 M hydrochloric acid medium

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