Chemical composition, antioxidant, antibacterial, and tyrosinase inhibition activity of extracts from Newhall navel orange (<scp><i>Citrus sinensis</i></scp> Osbeck cv. Newhall) peel

Guo, Can; Shan, Youxia; Yang, Zhiqiang; Zhang, Linyan; Ling, Wei; Liang, Yan; Ouyang, Zhigang; Zhong, Balian; Zhang, Jun

doi:10.1002/jsfa.10297

Cited by 63 publications

(40 citation statements)

References 41 publications

(103 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In β-carotene, this extract exhibited an IC 50 value of 0.23 mg/mL. Da Silva et al (2018) Guo et al (2020) for Citrus sinensis cv. Newhall peels extract.…”

Section: Antioxidant Effectsmentioning

confidence: 91%

Citrus species: Modern functional food and nutraceutical-based product ingredient

2021

View full text Add to dashboard Cite

Citrus is the most cultivated fruit crop in the world and occupies a place of considerable importance in the country’s economy. Almost 33% of the citrus fruits are processed for juice production; however, a great amount of wastes, including peels, segment membranes, and seeds are also produced. Indeed, citrus fruits consist of 45% juice, 26% pulp, 27% peels, and 2% seeds. Pruning, a cultural practice involving the removal of tree branches and limbs, was applied to improve fruit’s quality. A large amount of leaves are produced through pruning. These agri-food matrices contain a wide range of bioactive phytochemicals compared to fruits. The present review covers the past 5 years of research carried out in chemistry, health properties, and applications in food and nutraceutical industries of all portions of citrus fruit and its major bioactive compounds. Additionally, patents are also included.

show abstract

“…In β-carotene, this extract exhibited an IC 50 value of 0.23 mg/mL. Da Silva et al (2018) Guo et al (2020) for Citrus sinensis cv. Newhall peels extract.…”

Section: Antioxidant Effectsmentioning

confidence: 91%

Citrus species: Modern functional food and nutraceutical-based product ingredient

2021

View full text Add to dashboard Cite

show abstract

“…In addition to well-known medicinal plants, researchers have investigated the antibacterial activity of extracts from certain by-products of food consumption and synthesized green nanoparticles to valorize them in the search for new antimicrobials that may overcome antibiotic resistance [16][17][18][19][20][21][22][23][24][25]. Therefore, the aim of this study was to assess the antibacterial properties of aqueous and hydroalcoholic extracts of grapefruit peels as well as their inclusion in green-synthesized silver nanoparticles (AgNPs).…”

Section: Introductionmentioning

confidence: 99%

Antibacterial activity of grapefruit peel extracts and green-synthesized silver nanoparticles

et al. 2021

View full text Add to dashboard Cite

Background and Aim: The gradual loss of efficacy of conventional antibiotics is a global issue. Plant material extracts and green-synthesized nanoparticles are among the most promising options to address this problem. Therefore, the aim of this study was to assess the antibacterial properties of aqueous and hydroalcoholic extracts of grapefruit peels as well as their inclusion in green-synthesized silver nanoparticles (AgNPs). Materials and Methods: Aqueous and hydroalcoholic extracts (80% v/v) were prepared, and the volume and mass yields were determined. The synthesis of AgNPs was done in an eco-friendly manner using AgNO3 as a precursor. The nanoparticles were characterized by ultraviolet–vis spectrometry and photon cross-correlation spectroscopy. The antibacterial activity of the extracts was tested on three Gram-positive bacteria (Staphylococcus aureus ATCC 6538, clinical Enterococcus faecalis, and S. aureus) and two Gram-negative bacteria (two clinical Escherichia coli) using various concentrations of extracts (100, 50, 25, 12, and 5 mg/mL and 5% dimethyl sulfoxide as negative control). Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined using the microdilution method. Modulation of cefazoline and ampicillin on resistant E. coli and S. aureus strains was added to the mixture design response surface methodology with extreme vertices design, with the diameters of inhibition and the fractional inhibitory concentration index as responses and factors, respectively. The antibiotic, the ethanolic extract, and water varied from 0.1 MIC to 0.9 MIC for the first two and from 0 to 0.8 in proportion for the third. Validating the models was done by calculating the absolute average deviation, bias factor, and accuracy factor. Results: The volume yield of the EE and aqueous extract (AE) was 96.2% and 93.8% (v/v), respectively, whereas their mass yields were 7.84% and 9.41% (m/m), respectively. The synthesized AgNPs were very uniform and homogeneous, and their size was dependent on the concentration of AgNO3. The antibacterial activity of the two extracts was dose-dependent, and the largest inhibition diameter was observed for the Gram-positive bacteria (S. aureus ATCC 6538; AE, 12; EE, 16), whereas AgNPs had a greater effect on Gram-negative bacteria. The MICs (mg/mL) of the AEs varied from 3.125 (S. aureus ATCC 6538) to 12.5 (E. coli 1 and E. coli 2), whereas the MICs of the EEs varied from 1.5625 (S. aureus 1, S. aureus ATCC 6538, and E. faecalis) to 6.25 (E. coli 1). There was a significant difference between the MICs of AEs and EEs (p=0.014). The MBCs (mg/mL) of the AEs varied from 12.5 (S. aureus ATCC 6538) to 50 (S. aureus 1), whereas those of the EEs varied from 6.25 (S. aureus 1) to 25 (E. coli 1 and E. faecalis). Ethanolic grapefruit extracts demonstrated an ability to modulate cefazolin on E. coli and S. aureus but were completely indifferent to ampicillin on E. coli. Conclusion: Grapefruit peel extracts and their AgNPs exhibit antibacterial properties that can be exploited for the synthesis of new antimicrobials and their EEs may be efficiently used synergistically with other antibiotics against bacteria with intermediate susceptibility.

show abstract

“…Extracts prepared from mangosteen bark or fruit pericarp exhibited strong pH-dependent bacteriostatic and bactericidal effects against L. monocytogenes and S. aureus [70]. Ethyl acetate extract of Newhall orange peel showed the best antimicrobial effect due to the presence of sinensetin, 4 ,5,6,7-tetramethoxyflavone, nobiletin, 3,3 ,4 ,5,6,7-hexamethoxyflavone, and narirutin [71]. Punica granatum peels (Bhagwa) furnished extracts, endowing interesting antibacterial properties.…”

Section: Agro-food Wastes As Antimicrobialsmentioning

confidence: 99%

Nanotechnologies: An Innovative Tool to Release Natural Extracts with Antimicrobial Properties

et al. 2021

View full text Add to dashboard Cite

Site-Specific release of active molecules with antimicrobial activity spurred the interest in the development of innovative polymeric nanocarriers. In the preparation of polymeric devices, nanotechnologies usually overcome the inconvenience frequently related to other synthetic strategies. High performing nanocarriers were synthesized using a wide range of starting polymer structures, with tailored features and great chemical versatility. Over the last decade, many antimicrobial substances originating from plants, herbs, and agro-food waste by-products were deeply investigated, significantly catching the interest of the scientific community. In this review, the most innovative strategies to synthesize nanodevices able to release antimicrobial natural extracts were discussed. In this regard, the properties and structure of the starting polymers, either synthetic or natural, as well as the antimicrobial activity of the biomolecules were deeply investigated, outlining the right combination able to inhibit pathogens in specific biological compartments.

show abstract

Chemical composition, antioxidant, antibacterial, and tyrosinase inhibition activity of extracts from Newhall navel orange (Citrus sinensis Osbeck cv. Newhall) peel

Cited by 63 publications

References 41 publications

Citrus species: Modern functional food and nutraceutical-based product ingredient

Citrus species: Modern functional food and nutraceutical-based product ingredient

Antibacterial activity of grapefruit peel extracts and green-synthesized silver nanoparticles

Nanotechnologies: An Innovative Tool to Release Natural Extracts with Antimicrobial Properties

Contact Info

Product

Resources

About