Chemical composition, antioxidant and antimicrobial activity of the essential oil of the thyme and rosemary

Abozid, M. M.; Asker, Mohsen S.

doi:10.7813/2075-4124.2013/5-3/a.26

Cited by 10 publications

(4 citation statements)

References 49 publications

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“…Nevertheless, there are indications of its antioxidant and antibacterial activity. The composition of thyme EO was comparable with the composition previously reported, although the amount of some components in other EOs differs [37]. For rosemary EO, the amount of Linalool (13.34%) was higher for other reports that present 0.4-0.5% [38,39].…”

Section: Discussionsupporting

confidence: 85%

Synergy of Plant Essential Oils in Antibiotic Therapy to Combat Klebsiella pneumoniae Infections

Romo-Castillo,

Flores-Bautista,

Guzmán-Gutiérrez

et al. 2023

Pharmaceuticals

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Increased antibiotic resistance presents a health problem worldwide. The World Health Organization published a list of pathogens considered a priority for designing new treatments. Klebsiella pneumoniae (Kp) is a top-priority microorganism, highlighting the strains that produce carbapenemases. Developing new efficient therapies or complementing existing treatments is a priority, and essential oils (EOs) provide an alternative. EOs could act as antibiotic adjuvants and enhance antibiotic activity. Employing standard methodologies, the antibacterial activity of the EOs and their synergic effect with antibiotics were detected. A string test was used to identify the impact of the EOs over the hypermucoviscosity phenotype presented by Kp strains, and Gas Chromatography–Mass Spectrometry analysis identified EOs and the composition of EOs. The potential of EOs for designing synergistic therapies with antibiotics to combat the infection of KPC diseases was demonstrated. In addition, the alteration of the hypermucoviscosity phenotype was shown as the principal mechanism of a synergic action between EOs and antibiotics. The differential composition of the EOs lets us identify some molecules that will be analyzed. Synergic activity of EOs and antibiotics can provide a solid platform for combating multiresistant pathogens that represent a severe health sector problem, such as Kp infections.

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Section: Discussionsupporting

confidence: 85%

Synergy of Plant Essential Oils in Antibiotic Therapy to Combat Klebsiella pneumoniae Infections

Romo-Castillo,

Flores-Bautista,

Guzmán-Gutiérrez

et al. 2023

Pharmaceuticals

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“…The chemical compounds of the hydrodistilled THO (Table 2) was analyzed through a gas chromatography-spectrometry (GC-MS; Sigma 300 apparatus attached to a HP of 5970 300 mass spectrometer) system. Thyme essential oils (TEO) were analyzed by gas chromatography (Delsi 121C gas chromatograph) according to Abozid and Asker [22] (Table 2, Figure 2).…”

Section: Zinc Oxide Nanoparticles and Thyme Oil Preparationmentioning

confidence: 99%

Combined Supplementation of Nano-Zinc Oxide and Thyme Oil Improves the Nutrient Digestibility and Reproductive Fertility in the Male Californian Rabbits

Abdel-Wareth

Alkahtani

Alsyaad

et al. 2020

Animals

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The present study aimed to determine the effects of zinc oxide nanoparticles (ZnO-NPs), thyme oil (THO), or their combination on the nutrient digestibility coefficients, reproductive parameters, and some blood metabolites of male Californian rabbits. One hundred rabbits, 29-weeks of age (initial body weight 3.48 ± 0.08 kg) were randomly distributed into four groups, 25 rabbits each. Treatment groups were fed a control diet, a control diet supplemented with ZnO-NPs (100 mg/kg), THO (500 mg/kg), or combination of ZnO-NPs (100 mg/kg) and THO (500 mg/kg). The feeding trial lasted for 35 days. Results showed improvements in dry matter, crude protein, ether extract, and crude fiber in ZnO-NPs, THO, and their combination treated groups compared to those of control. Furthermore, semen volume, sperm motility, vitality, and morphology were significantly improved (p < 0.01) in ZnO-NPs and THO groups rather than the control. Both ZnO-NPs and THO, as either individual or combined treatments significantly improved the serum alanine amino-transferase (ALT), aspartate amino-transferase (AST), urea, and creatinine compared to the control. Moreover, serum concentrations of testosterone were significantly increased in rabbits supplemented with ZnO-NPs, THO, or their combination compared to those of control (p < 0.05). In conclusion, ZnO-NPs, THO, or their combination improved the digestibility of nutrients, liver/ kidney functions, semen characteristics, and testosterone concentration in male rabbits.

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“…Analysis of the chemical composition of hydrodistilled TEO (Table 2) was conducted using a gas chromatography-mass spectrometry (GC/MS) system as per Abozid and Asker [21]. The TEO was purchased from El Hawag Natural Oils Company, Cairo, Egypt.…”

Section: Chemical Analysismentioning

confidence: 99%

Productive and Physiological Response of Male Rabbits to Dietary Supplementation with Thyme Essential Oil

Abdel-Wareth

Metwally

2020

Animals

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The present study aimed at assessing the efficiency of thyme essential oil (TEO) as an alternative to antibiotics for improving the productive performance and serum metabolic profile of male rabbits. A total of one hundred and fifty 70-day-old male Californian rabbits were assigned to five dietary treatments, including a basal diet as a negative control (NC), a basal diet supplemented with an antibiotic as a positive control (PC), and a basal diet supplemented with 60, 120, or 180 mg/kg of TEO. The experiment period lasted for 60 days. Supplementation of TEO levels significantly (P < 0.01) increased daily body weight gain and improved feed conversion ratio of male Californian rabbits compared to NC and PC groups. Similarly, the TEO remarkably enhanced the semen characteristics of rabbits compared to NC and PC groups. Supplementation of TEO significantly decreased aspartate transaminase, alanine transaminase, urea, and creatinine compared with NC and PC groups. Supplementation with TEO increased serum testosterone concentration compared to NC and PC treatments. Our data demonstrate that TEO levels up to 180 mg/kg can play a major role as an alternative to dietary antibiotics, in improving the productive performance, semen quality, testosterone levels, and the kidney and liver functions in California male rabbits.

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Chemical composition, antioxidant and antimicrobial activity of the essential oil of the thyme and rosemary

Cited by 10 publications

References 49 publications

Synergy of Plant Essential Oils in Antibiotic Therapy to Combat Klebsiella pneumoniae Infections

Synergy of Plant Essential Oils in Antibiotic Therapy to Combat Klebsiella pneumoniae Infections

Combined Supplementation of Nano-Zinc Oxide and Thyme Oil Improves the Nutrient Digestibility and Reproductive Fertility in the Male Californian Rabbits

Productive and Physiological Response of Male Rabbits to Dietary Supplementation with Thyme Essential Oil

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