Chemical Composition, Antibacterial, and Anti-Inflammatory Activities of Essential Oils from Flower, Leaf, and Stem of Rhynchanthus beesianus

Chen, Qi; Zhao, Xiaoge; Lu, Tingya; Yang, Y.; Hong, Yi; Tian, Min-Yi

doi:10.1155/2021/5562461

Cited by 3 publications

(2 citation statements)

References 26 publications

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“…Research by Gachkar et al [ 71 ] has attributed the antimicrobial activity of some essential oils to the presence borneol, which has been identified as a major constituent of the essential oils obtained from the flowers, leaves, and stem of Rhynchanthus beesianus [ 72 ], which presented significant antibacterial activity against Bacillus subtilis , Enterococcus faecalis , S. aureus , Proteus vulgaris , P. aeruginosa , and E. coli .…”

Section: Resultsmentioning

confidence: 99%

Potentiation of the Activity of Antibiotics against ATCC and MDR Bacterial Strains with (+)-α-Pinene and (-)-Borneol

Leite-Sampaio

Gondim

Martins

et al. 2022

BioMed Research International

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The increasing rates of antimicrobial resistance have demanded the development of new drugs as conventional antibiotics have become significantly less effective. Evidence has identified a variety of phytocompounds with the potential to be used in the combat of infections caused by multidrug-resistant (MDR) bacteria. Considering the verification that terpenes are promising antibacterial compounds, the present research aimed to evaluate the antibacterial and antibiotic-modulating activity of (+)-α-pinene and (-)-borneol against MDR bacterial strains. The broth microdilution method was used to determine the minimum inhibitory concentration (MIC) of the compounds and antibiotics and further evaluate the intrinsic and associated antibiotic activity. These analyses revealed that (+)-α-pinene showed significant antibacterial activity only against E. coli ( MIC = 512 μ g . m L − 1 ), while no significant inhibition of S. aureus and P. aeruginosa growth was observed ( MIC ≥ 1024 μ g m L − 1 ). However, when combined with antibiotics, this compound induced a significant improvement in the activity of conventional antibiotics, as observed for ciprofloxacin, amikacin, and gentamicin against Staphylococcus aureus, as well as for amikacin and gentamicin against Escherichia coli, and amikacin against Pseudomonas aeruginosa. On the other hand, (-)-borneol was found to inhibit the growth of E. coli and enhance the antibiotic activity of ciprofloxacin and gentamicin against S. aureus. The present findings indicate that (+)-α-pinene and (-)-borneol are phytocompounds with the potential to be used in the combat of antibacterial resistance.

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Section: Resultsmentioning

confidence: 99%

Potentiation of the Activity of Antibiotics against ATCC and MDR Bacterial Strains with (+)-α-Pinene and (-)-Borneol

Leite-Sampaio

Gondim

Martins

et al. 2022

BioMed Research International

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“…The diameter of the inhibition zone (DIZ) was determined with the disc diffusion method described by Chen et al [21]. Briefly, 100 µL of bacterial suspension (1 × 10 6 CFU/mL) was evenly spread on Mueller-Hinton agar medium.…”

Section: Antibacterial Activitymentioning

confidence: 99%

Chemical Composition, Antibacterial, Enzyme-Inhibitory, and Anti-Inflammatory Activities of Essential Oil from Hedychium puerense Rhizome

et al. 2021

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Hedychium puerense, a perennial rhizomatous herb, is used as an ornamental, medicinal, and edible plant in Yunnan Province, China. Essential oils from Hedychium plants are widely used in perfumes and traditional medicine, but there are no studies on the constituents and bioactivities of H. puerense essential oil (EO). Therefore, this study was designed to explore the chemical composition, antibacterial, enzyme-inhibitory, and anti-inflammatory activities of H. puerense rhizome EO. The gas chromatography with flame ionization or mass selective detection (GC-FID/MS) results indicated that H. puerense EO was mainly composed of linalool (26.5%), β-pinene (18.6%), γ-terpinene (12.1%), terpinen-4-ol (7.7%), α-pinene (5.8%), sabinene (4.9%), E-nerolidol (4.1%), and p-cymene (3.6%). For biological activities, H. puerense EO displayed broad-spectrum antibacterial properties against Enterococcus faecalis, Bacillus subtilis, Staphylococcus aureus, Proteus vulgaris, Pseudomonas aeruginosa, and Escherichia coli with diameter of inhibition zone (DIZ) values ranging from 7.44 to 10.30 mm, a minimal inhibitory concentration (MIC) of 3.13–6.25 mg/m), and a minimal bactericidal concentration (MBC) of 3.13–12.50 mg/mL. Moreover, the EO significantly inhibited acetylcholinesterase (AChE) (IC50 = 0.94 ± 0.02 mg/mL) and butyrylcholinesterase (BChE) (IC50 = 1.32 ± 0.06 mg/mL) activities, and exhibited a moderate inhibitory effect on α-glucosidase (IC50 = 5.42 ± 0.32 mg/mL) and tyrosinase (IC50 = 3.23 ± 0.21 mg/mL). Furthermore, the EO significantly suppressed the secretion of the pro-inflammatory mediator, nitric oxide (NO) (99.23 ± 0.26%), cytokines tumor necrosis factor-α (TNF-α) (97.14 ± 0.11%), and interleukin-6 (IL-6) (82.42 ± 0.16%) in lipopolysaccharide (LPS)-stimulated RAW264.7 cells at 250 μg/mL without cytotoxicity. Hence, H. puerense EO can be considered a bioactive, natural product that has great potential for utilization in the fields of food, cosmetics, and pharmaceutics.

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Insecticidal activities of the essential oil of Rhynchanthus beesianus rhizomes and its constituents against two species of grain storage insects

Pan

et al. 2022

Zeitschrift Für Naturforschung C

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The aim of this research was to evaluate insecticidal activities of the essential oil of Rhynchanthus beesianus rhizomes against adults of Liposcelis entomophila and Tribolium castaneum. Gas chromatography-mass spectrometry analyses revealed the presence of 44 compounds with β-eudesmol (19.1%), elemol (8.1%), α-terpineol (8.0%), methyl eugenol (6.5%), and caryophyllene (4.8%) being the major constituents. Bioactivity-directed chromatographic separation of the oil led to the isolation of four constituents, elemol, β-eudesmol, methyl eugenol, and α-terpineol. The essential oil exhibited fumigant toxicity against the adults of L. entomophila and T. castaneum with LC50 values of 0.57 and 4.96 mg/L air while the two isolates, methyl eugenol and α-terpineol possessed fumigant toxicity against the booklice (LC50 = 0.15 and 0.48 mg/L air, respectively) and the beetles (LC50 = 1.81 and 4.96 mg/L air, respectively). The oil also possessed contact toxicity against the booklice and the beetles with LD50 values of 121.56 μg/cm2 and 54.93 μg/adult, respectively, while the two isolates β-eudesmol and elemol showed contact toxicity against L. entomophila (LD50 = 99.21 and 35.19 μg/cm2, respectively) and T. castaneum (LD50 = 35.26 and 8.89 μg/adult, respectively). The results indicate that the oil of R. beesianus rhizomes and its isolates have potential as a source for natural insecticides.

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Chemical Composition, Antibacterial, and Anti-Inflammatory Activities of Essential Oils from Flower, Leaf, and Stem of Rhynchanthus beesianus

Cited by 3 publications

References 26 publications

Potentiation of the Activity of Antibiotics against ATCC and MDR Bacterial Strains with (+)-α-Pinene and (-)-Borneol

Potentiation of the Activity of Antibiotics against ATCC and MDR Bacterial Strains with (+)-α-Pinene and (-)-Borneol

Chemical Composition, Antibacterial, Enzyme-Inhibitory, and Anti-Inflammatory Activities of Essential Oil from Hedychium puerense Rhizome

Insecticidal activities of the essential oil of Rhynchanthus beesianus rhizomes and its constituents against two species of grain storage insects

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