Chemical composition, antibacterial activity and study of the interaction mechanisms of the main compounds present in the Alpinia galanga rhizomes essential oil

Zhou, Changqian; Li, Changzhu; Siva, S.; Cui, Haiying; Lin, Lin

doi:10.1016/j.indcrop.2021.113441

Cited by 62 publications

(31 citation statements)

References 71 publications

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“…Bonilla et al [32] also showed that the cohesion was reduced because of the discontinuity of the polymer network due to MOEO nanoemulsion. Similar trends were found in CMCSpullulan active films containing galangal essential oil and in xanthan gum/locust bean gum films containing tea polyphenols [33].…”

Section: Wvp and Water Contact Anglesupporting

confidence: 77%

Effect of Melissa officinalis L. Essential Oil Nanoemulsions on Structure and Properties of Carboxymethyl Chitosan/Locust Bean Gum Composite Films

Zhang

Xie

et al. 2022

Membranes

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This study aimed to develop active films based on carboxymethyl chitosan (CMCS)/locust bean gum (LBG) films containing Melissa officinalis L. essential oil (MOEO) nanoemulsions. The results showed that the active films incorporated with MOEO nanoemulsion resulted in an increase in the elongation of break, water resistance and improved the film hydrophilicity. Elongation of break increased from 18.49% to 27.97% with the addition of 4% MOEO nanoemulsion. Water resistance was decreased from 56.32% to 25.43%, and water contact angle was increased from 75.13 to 83.86 with the addition of 4% MOEO nanoemulsion. However, the water vapor barrier properties and tensile strength decreased with the addition of MOEO nanoemulsions. The scanning electron microscopic images and Fourier transform infrared spectroscopy results showed that the MOEO was very compatible with the film materials and dispersed evenly in the films. At the same time, the addition of MOEO nanoemulsion significantly enhanced antioxidant and antibacterial activities of C/L-MOEO films. The antioxidant and antimicrobial activities of C/L-MOEO films were increased from 7.16% to 33.81% and 3.52% to 54.50%, respectively. In general, C/L-MOEO film has great application prospects.

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Section: Wvp and Water Contact Anglesupporting

confidence: 77%

Effect of Melissa officinalis L. Essential Oil Nanoemulsions on Structure and Properties of Carboxymethyl Chitosan/Locust Bean Gum Composite Films

Zhang

Xie

et al. 2022

Membranes

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“… Dai et al (2021) reported that the strain cells treated with Litsea cubeba essential oil lead to disordered function of cell membranes and obvious intracellular injury appeared. Zhou et al (2021) showed that treatment of E. coli with Alpinia galanga rhizomes essential oil can stimulate the efflux of intracellular material. Liu W. et al (2020) interpreted that cell membranes and walls of P. fluorescens and S. putrefaciens treated with Daphnetin were disrupted and resolved, and the cytoplasm of the bacteria leaked, creating a clear cavity.…”

Section: Resultsmentioning

confidence: 99%

“…In general, Lux systems can affect the formation of biofilms in Vibrio species. D-limonene, linalool, and citronellol were the main components of MOEO, which have been shown to inhibit the QS system of bacteria (Deborah and Groisman, 2013;Ding et al, 2018;Zhang et al, 2018;He et al, 2019;Dai et al, 2021;Liu et al, 2021;Zhou et al, 2021). D-limonene can inhibit the activity of signaling molecules by degrading them or reducing their production (He et al, 2019).…”

Section: Melissa Officinalis L Essential Oil Suppressed the Virulence...mentioning

confidence: 99%

The Antimicrobial Effect of Melissa officinalis L. Essential Oil on Vibrio parahaemolyticus: Insights Based on the Cell Membrane and External Structure

Pei

Qiu

et al. 2022

Front. Microbiol.

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The study was to evaluate the antimicrobial impacts on Melissa officinalis L. essential oil (MOEO) against Vibrio parahaemolyticus. The minimum inhibitory concentration (MIC) of MOEO on Vibrio parahaemolyticus was 1 μL⋅mL–1. The kill-time curve exhibited that MOEO had good antimicrobial activity. The analysis of cellular ingredients leakage and cell viability illustrated that MOEO has destruction to the morphology of the cell membrane. The damage to the membrane integrity by MOEO has been confirmed by transmission and scanning electron microscopy, obvious morphological and ultrastructural changes were observed in the treated bacterial cells. The MOEO at 0.5 μL⋅mL–1 can inhibit the biofilm formation, biofilm motility, and extracellular polysaccharide production. Meanwhile, the qPCR results exhibited MOEO inhibited the expression of virulence genes. The findings showed that MOEO exerted its antimicrobial effect mainly by destroying the membrane, which indicated its potential as a natural food preservative.

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“…Kaempferol and isorhamnetin have also been proven to affect fibrosis, and the pharmacological effects of isorhamnetin are related to the regulation of NF-κB, PI3K/AKT, MAPK and other signaling pathways ( Li et al, 2016 ; Gong et al, 2020 ; Kim et al, 2015 ). The high affinity between active compounds (kaempferol, quercetin) and targets (SRC and AKT1) were verified using molecular docking, which has been widely used to study the interaction between small molecule and target protein via visualizing the binding mode for the structure-based drug discovery ( Zhou et al, 2021 ). Reports showed that quercetin and kaempferol restrained the PI3K-Akt signal pathway by inhibiting the expression of p-Akt1 ( Lu et al, 2018 ; Imran et al, 2019), and the latter compound also suppressed the expression of Src contributing to its anti-inflammatory activity (Imran et al, 2019).…”

Section: Discussionmentioning

confidence: 99%

Anti-Liver Fibrosis Activity and the Potential Mode of Action of Ruangan Granules: Integrated Network Pharmacology and Metabolomics

et al. 2022

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Ruangan granules (RGGs) have been used to treat liver fibrosis with good clinical efficacy for many years. However, the potential mechanism of action of RGGs against liver fibrosis is still unclear. In this study, we evaluated the quality and safety of this preparation and aimed to explore the anti-liver fibrosis activity and potential mode of action of RGGs using network pharmacology and metabolomics. The results showed that RGGs contained abundant ferulic acid, salvianolic acid B and paeoniflorin, and at the given contents and doses, RGGs were safe and presented anti-liver fibrosis activity. They presented anti-liver fibrosis activity by improving liver function (ALT and AST, p < 0.01) and pathology and decreasing fibrosis markers in the serum of rats caused by CCl4, including HA, LN, PC III, HYP, CoII-V, and α-SMA, and the oxidant stress and inflammatory response were also alleviated in a dose-dependent manner, especially for high-dose RGGs (p < 0.01). Further studies showed that RGGs inhibited the activation of the PI3K-Akt signaling pathway in rats induced by CCl4, regulated pyrimidine metabolism, improved oxidative stress and the inflammatory response by regulating mitochondrial morphology, and alleviated liver fibrosis. Luteolin, quercetin, morin and kaempferol were active compounds and presented the cytotoxicity toward to LX-02 cells. This study provides an overall view of the mechanism underlying the action of RGGs protecting against liver fibrosis.

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Chemical composition, antibacterial activity and study of the interaction mechanisms of the main compounds present in the Alpinia galanga rhizomes essential oil

Cited by 62 publications

References 71 publications

Effect of Melissa officinalis L. Essential Oil Nanoemulsions on Structure and Properties of Carboxymethyl Chitosan/Locust Bean Gum Composite Films

Effect of Melissa officinalis L. Essential Oil Nanoemulsions on Structure and Properties of Carboxymethyl Chitosan/Locust Bean Gum Composite Films

The Antimicrobial Effect of Melissa officinalis L. Essential Oil on Vibrio parahaemolyticus: Insights Based on the Cell Membrane and External Structure

Anti-Liver Fibrosis Activity and the Potential Mode of Action of Ruangan Granules: Integrated Network Pharmacology and Metabolomics

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