2021
DOI: 10.3390/beverages8010001
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Chemical Composition and Polyphenolic Compounds of Red Wines: Their Antioxidant Activities and Effects on Human Health—A Review

Abstract: Red wine, an alcoholic beverage is composed of a spectrum of complex compounds such as water, alcohol, glycerol, organic acid, carbohydrates, polyphenols, and minerals as well as volatile compounds. Major factors that affect the levels of phenolic compounds in red wines are the variety of grapes and the storage of the wines. Among the constituents of red wine, phenolic compounds play a crucial role in attributes including color and mouthfeel and confer beneficial properties on health. Most importantly, phenoli… Show more

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Cited by 42 publications
(30 citation statements)
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“…The use of red wine contributed to a statistically significant lower content of hydroperoxides and malonaldehyde (MDA) in the finished sausages (samples SD25 and SD50), (p < 0.05), compared to the wine-free sample (Figure 1). These data correlate well with the antioxidant activity against free radicals reported for polyphenols (Nemzer et al, 2022). Slower lipid oxidation after addition of 5% red wine to the sausage batter was also observed by Feng et al (2018), who, however, found accelerated lipid oxidation in the manufacture of a type of uncured frankfurter when the wine quantity was increased to 10% (v/w).…”
Section: Lipid Oxidation Analysissupporting
confidence: 86%
“…The use of red wine contributed to a statistically significant lower content of hydroperoxides and malonaldehyde (MDA) in the finished sausages (samples SD25 and SD50), (p < 0.05), compared to the wine-free sample (Figure 1). These data correlate well with the antioxidant activity against free radicals reported for polyphenols (Nemzer et al, 2022). Slower lipid oxidation after addition of 5% red wine to the sausage batter was also observed by Feng et al (2018), who, however, found accelerated lipid oxidation in the manufacture of a type of uncured frankfurter when the wine quantity was increased to 10% (v/w).…”
Section: Lipid Oxidation Analysissupporting
confidence: 86%
“…Wine is produced by fermentation with fresh grape or grape must, which is carried out by yeasts via the consumption grape sugars, subsequently producing ethanol and CO 2 [ 98 ]. A variety of other substances, such as organic acids, polysaccharides and polyphenols, are also produced or transported from grape in the processes of the wine production, storage and maturation, some of which are responsible for the sensory properties (such as flavor, color and taste) and health benefits of wine [ 99 ]. Many health benefits of wine are attributed to resveratrol, which is mainly found in grape skins and enters into wine through maceration and fermentation.…”
Section: Applications Of Grape In the Food Industrymentioning
confidence: 99%
“…Nowadays, it is a generally accepted premise that moderate and regular consumption of red wine might be the key to the prevention of cardiovascular, oncological and neurodegenerative diseases, type 2 diabetes and other chronic diseases [ 106 ]. However, winemaking by-products present a much higher total content of anthocyanins, stilbenes, and flavanols, being much more effective in antioxidant therapy than wine itself [ 107 ].…”
Section: Potential Uses Of Grapevine Waste-derived Products In Biomed...mentioning
confidence: 99%
“…Thus, flavonoids from grape pomace can decrease the production of RONS (reactive oxygen species and nitrogen) by inhibiting the enzymes that produce them, in particular NOX4 (NADPH oxidase 4), eNOS (endothelial nitric oxide synthase), COX2 (ciclooxigenase 2) and SOD1 and 2 (superoxide dismutase 1 and 2), upregulating NF-κB (nuclear factor-kappa B) and downregulating Nrf2 (nuclear factor erythroid 2-related factor 2) pathways [ 109 ]. Enzymatic grape pomace extracts can adapt, in vitro, the transcription of 7α-hydroxylase cholesterol and 27-hydroxylase sterol [ 110 ], and ex vivo tests in Wistar rats show lowering levels of VLDL cholesterol and triacylglycerol [ 106 ]. Ulcerative colitis, induced by acetic acid, showed ulceration, edema and erosions to the colon in laboratory mice.…”
Section: Potential Uses Of Grapevine Waste-derived Products In Biomed...mentioning
confidence: 99%