Chemical Composition and Evaluation of Antitumoral Activity of Leaf and Root Essential Oils of Conyza canadensis (Asteraceae)

Aragão, Lucas Wagner Ribeiro; Fernandes, Shaline Séfara Lopes; Mallmann, Viviane; Facco, Janaina T.; Matos, Maria de Fátima Cepa; Cabral, Márcia Regina Pereira; Carvalho, João Ernesto de; Ruiz, Ana Lúcia T. G.; Cardoso, Cláudia Andréa Lima; Silva, Rogério César de Lara da; Anjos, Ademir dos; Simionatto, Euclésio

doi:10.17807/orbital.v11i5.1376

Cited by 2 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The essential oil of C. canadensis from Turkey, Pakistan, and Brazil, was dominated by limonene and polyacetylene derivatives, mainly (Z)-lachnophyllum ester and matricaria ester isomers [8,[10][11][12]. In most reports, limonene dominated the EO obtained from whole aerial parts, while polyacetylene derivatives dominated the essential oil obtained from the roots [4,5,9]. Noticeably, the CCHD-EO of different aerial parts was rich in (2E,8Z)matricaria ester isomer which was almost absent in EO of the plant from other regions.…”

Section: Cchd-eos Data Analysismentioning

confidence: 99%

“…Literature surveys revealed that several Conyza species, including C. canadensis, were subjected to investigation of their volatile composition [4,5,[8][9][10][11][12]. A previous phytochemical screening of C. canadensis secondary metabolites revealed the presence of polyacetylene derivatives [13], triterpenes [14][15][16], flavones, and phenolic compounds [17,18].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Conyza canadensis from Jordan: Phytochemical Profiling, Antioxidant, and Antimicrobial Activity Evaluation

Barhoumi,

Shakya,

Al-Fawares

et al. 2024

Molecules

View full text Add to dashboard Cite

In this investigation, the chemical composition of the hydro-distilled essential oil (HD-EO), obtained from the fresh aerial parts (inflorescence heads (Inf), leaves (L), and stems (St)) of Conyza canadensis growing wild in Jordan was determined by GC/MS. Additionally, the methanolic extract obtained from the whole aerial parts of C. canadensis (CCM) was examined for its total phenolic content (TPC), total flavonoids content (TFC), DPPH radical scavenging activity, iron chelating activity and was then analyzed with LC-MS/MS for the presence of certain selected phenolic compounds and flavonoids. The GC/MS analysis of CCHD-EOs obtained from the different aerial parts revealed the presence of (2E, 8Z)-matricaria ester as the main component, amounting to 15.4% (Inf), 60.7% (L), and 31.6% (St) of the total content. Oxygenated monoterpenes were the main class of volatile compounds detected in the Inf-CCHD-EO. However, oils obtained from the leaves and stems were rich in polyacetylene derivatives. The evaluation of the CCM extract showed a richness in phenolic content (95.59 ± 0.40 mg GAE/g extract), flavonoids contents (467.0 ± 10.5 mg QE/ g extract), moderate DPPH radical scavenging power (IC50 of 23.75 ± 0.86 µg/mL) and low iron chelating activity (IC50 = 5396.07 ± 15.05 µg/mL). The LC-MS/MS profiling of the CCM extract allowed for the detection of twenty-five phenolic compounds and flavonoids. Results revealed that the CCM extract contained high concentration levels of rosmarinic acid (1441.1 mg/kg plant), in addition to caffeic acid phenethyl ester (231.8 mg/kg plant). An antimicrobial activity assessment of the CCM extract against a set of Gram-positive and Gram-negative bacteria, in addition to two other fungal species including Candida and Cryptococcus, showed significant antibacterial activity of the extract against S. aureus with MIC value of 3.125 µg/mL. The current study is the first phytochemical screening for the essential oil and methanolic extract composition of C. canadensis growing in Jordan, its antioxidant and antimicrobial activity.

show abstract

Section: Cchd-eos Data Analysismentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Conyza canadensis from Jordan: Phytochemical Profiling, Antioxidant, and Antimicrobial Activity Evaluation

Barhoumi,

Shakya,

Al-Fawares

et al. 2024

Molecules

View full text Add to dashboard Cite

show abstract

“…Due to its diuretic property, it is also useful in situations of oedema and obesity accompanied by fluid retention (Shakirullah et al, 2011). Studies conducted by Ayaz et al (2017) and Aragão et al (2019) detected limonene, caryophyllene oxide, spathulenol and beta-pinene as the major constituents of the essential oil of C. canadensis. Queiroz et al (2012) performed the systematic fractionation guided by bioassays using extract of C. canadensis and identified three substances with antifungal activity among them (4Z)-lachnophyllum lactone (LACH) (Figure 1).…”

mentioning

confidence: 99%

Bioactive compound isolated from Conyza canadensis combined with physical treatments for the control of green mould in Orange

Terao

Queiroz

Maia

2022

Journal of Phytopathology

View full text Add to dashboard Cite

Orange (Citrus sinensis L. Osbeck) plays an important role among Brazilian fruits, with a yearly yield of around 17 million tons in an area of approximately 600,000 ha, representing revenues of U$ 2 billion per year. Brazil exports 30,000 tons of fresh oranges and more than 1 million tons of fresh juice per year, placing the country as the world's leading exporter of orange juice, representing 85% of the global market (Revista Agrobrasil, 2020).Green mould, caused by Penicillium digitatum (Pers.) Sacc, is the major postharvest disease in citrus in all producing countries, and its occurrence depends on climatic conditions and fruit handling, from the orchard to the arrival at the end consumer. The onset of symptoms occurs mainly during storage and transport, reducing both the quality and quantity of marketable fruits (Terao et al., 2017).Currently, the widely used way to control these losses is through the application of fungicides in postharvest treatments, which can leave toxic residues in the fruit (Hjorth et al., 2011). Therefore, the availability of clean technologies and alternatives to the use of fungicides is essential. Among them, bioactive compounds obtained from plants, as well as physical treatments, such as hot water treatment and UV-C radiation, stand out.

show abstract

Chemical Composition and Evaluation of Antitumoral Activity of Leaf and Root Essential Oils of Conyza canadensis (Asteraceae)

Cited by 2 publications

References 0 publications

Conyza canadensis from Jordan: Phytochemical Profiling, Antioxidant, and Antimicrobial Activity Evaluation

Conyza canadensis from Jordan: Phytochemical Profiling, Antioxidant, and Antimicrobial Activity Evaluation

Bioactive compound isolated from Conyza canadensis combined with physical treatments for the control of green mould in Orange

Contact Info

Product

Resources

About