Chemical Composition and Biological Activities of Leaf Essential Oil of Syzygium myrtifolium from Eastern India

Jena, Sudipta; Ray, Asit; Sahoo, Ambika; Das, Purnima; Dash, Khirabdhi Tanaya; Kar, Subrat Kumar; Nayak, Sanghamitra; Panda, Pratap Chandra

doi:10.1080/0972060x.2021.1947897

Cited by 13 publications

(14 citation statements)

References 54 publications

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“…The yield of essential oils S. myrtifolium is 0.435 with the main constituents β-pinene (9.95%), trans-caryophyllene (9.27%), linalool (7.46%), and α-terpineol (4.82%). The essential oil of S. myrtifolium derived from eastern India was reported to contain δ-cadinol (29.53 %), caryophyllene oxide (26.25 %), and cyclocolorenone (7.7 %) as the main compounds based on GC/MS analysis (Jena et al, 2021). The main constituents of essential oils S. polycephalum are α-bergamotene (5.57%), nerolidol (10.84%), trans-caryophyllene (1.11%), trans-farnesyl acetate (0.72%).…”

Section: Results and Discussion Chemical Compound Analysismentioning

confidence: 99%

GC-MS Analysis and Antibacterial Activity of Essential Oils of Five Syzygium Species Leaves

et al. 2023

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The essential oil can inhibit pathogenic bacterial activities, which can be developed to be a natural preservative for food. This research aimed to evaluate the antibacterial activity of the essential oils from five species Syzygium on Bacillus cereus, Escherichia coli, Listeria monocytogenes, Staphylococcus aureus, and Salmonella enterica sv Typhimurium. The research results show that five Syzygium sp. Essential oils have moderate antibacterial properties with a minimum inhibitory concentration (MIC) value of 250 ‒ 500 μg/mL. S. polyanthum essential oils have the highest antibacterial activity than the rest species on B. cereus at 250 μg/mL. Meanwhile, the essential oil of S. polycephalum also showed the highest antibacterial activity with a MIC value of 250 μg/mL against L. monocytogenes. The chemical component analysis using GC-MS shows the main constituents farnesol, nerolidol, and n-decanal, presenting the antibacterial effect.

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Section: Results and Discussion Chemical Compound Analysismentioning

confidence: 99%

GC-MS Analysis and Antibacterial Activity of Essential Oils of Five Syzygium Species Leaves

et al. 2023

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“…The RAW 264.7 cells were treated with varying concentrations of essential oils (12.5 and 25 µg/mL), followed by treatment with LPS (1 µg/mL) at 37 °C for 24 h. Subsequently, the level of NO production in the culture medium was measured using a Griess reagent [ 95 ]. Then, Griess reagent (100 μL) was added to the culture medium (100 μL) and incubated for 10 min at 37 °C, followed by measurement of optical density at 540 nm.…”

Section: Methodsmentioning

confidence: 99%

Neocinnamomum caudatum Essential Oil Ameliorates Lipopolysaccharide-Induced Inflammation and Oxidative Stress in RAW 264.7 Cells by Inhibiting NF-κB Activation and ROS Production

et al. 2022

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Neocinnamomum caudatum (Lauraceae) plant is used in the traditional system of medicine and is considered a potential source of edible fruits, spices, flavoring agents and biodiesel. The leaves, bark and roots of the species are used by local communities for the treatment of inflammatory responses, such as allergies, sinusitis and urinary tract infections. However, there is no scientific evidence to support the molecular mechanism through which this plant exerts its anti-inflammatory effect. The aim of the current research was to characterize the chemical constituents of bark (NCB) and leaf (NCL) essential oil of N. caudatum and to elucidate its anti-inflammatory action in lipopolysaccharide (LPS)-treated RAW 264.7 cells. Essential oils extracted by hydrodistillation were further subjected to gas chromatography mass spectrometry (GC-MS) analysis. The major constituents in bark essential oil identified as β-pinene (13.11%), α-cadinol (11.18%) and α-pinene (10.99%), whereas leaf essential oil was found to be rich in β-pinene (45.21%), myrcene (9.97%) and α-pinene (9.27%). Treatment with NCB and NCL at a concentration of 25 µg/mL exerted significant anti-inflammatory activity by significantly reducing LPS-triggered nitric oxide (NO) production to 45.86% and 61.64%, respectively, compared to the LPS-treated group. In the LPS-treated group, the production of proinflammatory cytokines, such as tumor necrosis factor (TNF)-α, interleukin (IL)-6 and IL-1β, decreased after treatment with essential oil, alleviating the mRNA levels of inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2. The essential oil also inhibited the production of intracellular ROS and attenuated the depletion of mitochondrial membrane potential in a concentration-dependent manner. Pretreatment with NCB also reduced nuclear factor kappa-B (NF-κB)/p65 translocation and elevated the levels of endogenous antioxidant enzymes in LPS-induced macrophages. The present findings, for the first time, demonstrate the anti-inflammatory potential of both bark and leaf essential oils of N. caudatum. The bark essential oil exhibited a significantly more important anti-inflammatory effect than the leaf essential oil and could be used as a potential therapeutic agent for the treatment of inflammatory diseases.

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“…The percentages and the retention indices of the identified oil components were listed in Table 2 and 3 in the order of their elution on the HP-5MS column. Essential oils from Syzygium attopeuense and Syzygium tonkinense 2011; Saroj et al, 2015;Petrachaianan et al, 2019;Jugreet and Mahomoodally, 2020;Jena et al, 2021). This difference may be attributed to different factors such as the nature and age of the plants, geographical areas, time of collection, as well as the differences in the parts of the plants used for analysis (Thinh et al, 2022).…”

Section: Yields and Chemical Constituents Of Essential Oilsmentioning

confidence: 99%

Chemical composition, antimicrobial and larvicidal activities of essential oils of two Syzygium species from Vietnam

et al. 2024

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The present study is the first to investigate the chemical composition, antimicrobial and larvicidal activities of the essential oils from the leaves of Syzygium attopeuense (Gagnep.) Merr. & L.M.Perry and Syzygium tonkinense (Gagnep.) Merr. & L.M.Perry collected in Vietnam. The essential oils were extracted by hydrodistillation and analyzed by GC and GC–MS. The study indicated the presence of a high percentage of sesquiterpenes in both investigated essential oils. The major components of S. attopeuense essential oil were bicyclogermacrene (24.26%), (E)-caryophyllene (11.72%), and (E)-β-ocimene (6.75%), whereas S. tonkinense essential oil was dominated by (E)-caryophyllene (80.80%). The antimicrobial activity of essential oils was evaluated by broth microdilution assay to determine the minimum inhibitory concentration (MIC) and median inhibitory concentration (IC50). Both essential oils exhibited remarkable inhibitory activity against all tested Gram-positive bacteria and yeast than Gram-negative bacteria. Among them, essential oils of S. attopeuense and S. tonkinense possessed the strongest activity against Enterococcus faecalis (MIC = 4.00 μg/mL; IC50 = 1.69 μg/mL) and Candida albicans (MIC = 16.00 μg/mL; IC50 = 8.67 μg/mL), respectively. Furthermore, the larvicidal activity of essential oils was tested using fourth-instar larvae of Aedes aegypti. Results from the larvicidal test revealed that both essential oils had an excellent inhibitory effect against A. aegypti larvae with LC50 values from 25.55 to 30.18 μg/mL and LC90 values from 33.00 to 39.01 μg/mL. Our findings demonstrate that the essential oil extracted from S. attopeuense and S. tonkinense are potential sources of natural antimicrobials and can act as inexpensive mosquito larvicidal agents.

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Chemical Composition and Biological Activities of Leaf Essential Oil of Syzygium myrtifolium from Eastern India

Cited by 13 publications

References 54 publications

GC-MS Analysis and Antibacterial Activity of Essential Oils of Five Syzygium Species Leaves

GC-MS Analysis and Antibacterial Activity of Essential Oils of Five Syzygium Species Leaves

Neocinnamomum caudatum Essential Oil Ameliorates Lipopolysaccharide-Induced Inflammation and Oxidative Stress in RAW 264.7 Cells by Inhibiting NF-κB Activation and ROS Production

Chemical composition, antimicrobial and larvicidal activities of essential oils of two Syzygium species from Vietnam

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