Chemical composition and antioxidant and radical‐scavenging activities of Periploca laevigata root bark extracts

Hajji, Mohamed; Masmoudi, Ons; Ellouz-Triki, Yosra; Siala, Rayda; Gharsallah, Néji; Nasri, Monçef

doi:10.1002/jsfa.3532

Cited by 49 publications

(24 citation statements)

References 76 publications

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“…In addition, the plant extracts was significantly higher than that of the standards. The observed reductive potential of the extracts is as a result of the presence of hydrophilic polyphenolic compounds (Mohammed et al, 2008;Omoruyi et al, 2012). The finding is in full agreement with other reports which showed that the reductive potential of plant extracts corresponds with the amount of phenolic constituents present (Amin et al, 2006).…”

Section: Antioxidant Assaysupporting

confidence: 91%

Phytochemical constituents and antioxidant properties of acetone extract of Cleome gynandra (L.) growing in the Eastern Cape, South Africa.

Sowunmi¹,

Afolayan²

2015

Afr. J. Trad. Compl. Alt. Med.

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Background: Several wild vegetables have been reported for their therapeutic benefits in South Africa. Many of these plants including Cleome gynandra (L.) lack scientific reports on its significance in folkloric medicine. Therefore, this study was undertaken to evaluate quantitatively the compositions of phytochemicals and antioxidant properties of acetone extract of different parts of C. gynandra. Materials and Method: Antioxidant activities were assessed against ferric reducing power, ABTS (2, 2'-azino-bis-3-ethyl benzothiazoline-6-sulfonic acid) diammonium salt, DPPH (1, 1-diphenyl-2-picrylhydrazyl) and NO (nitric oxide) radical scavenging activities. Total phenolics, flavonoids, flavanols, proanthocyanidins, tannins, saponins and alkaloids were also investigated. Results: Amongst the different plant parts, the leaf extract had the highest concentration of total phenolics (126.79 ± 0.55 mg/g), flavonoids (40.58 ± 0.06 mg/g) and flavanols (42.41 ± 0.05 mg/g) while the stem extract had the highest amount of proanthocyanidins (419.01 ± 0.67 mg/g) compared to the leaves (403.29 ± 0.89 mg/g) and fruits (107.18 ± 0.59 mg/g). The reducing power of the extracts was significantly higher than that of the standard drugs used in a concentration dependent manner. The activities of the plant extracts against ABTS, DPPH and NO radicals were dose responsive with IC 50 value of 0.2, 0.1 and 0.03 mg/g respectively. Conclusion: C. gynandra possesses high secondary metabolites which accounts for its strong antioxidant ability thus justifying its use as natural occurring antioxidants in folkloric medicine. The study encourages a regular consumption of this wild vegetable in order to avert oxidative stress related diseases.

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Section: Antioxidant Assaysupporting

confidence: 91%

Phytochemical constituents and antioxidant properties of acetone extract of Cleome gynandra (L.) growing in the Eastern Cape, South Africa.

Sowunmi¹,

Afolayan²

2015

Afr. J. Trad. Compl. Alt. Med.

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“…The reduction capacity of the extract depends on the presence of reductones, which break the free radical chain by donating a hydrogen atom (Mohamed et al, 2009). In the present Study, an increase in reducing power with an increase in the concentration of the extract have been observed which is in agreement with the reports of Kumar et al, (2012) and Kalaivani and Mathew (2010).…”

Section: Discussionsupporting

confidence: 93%

In-vitro assessment of antioxidant potential of rotula aquatic lour extract

Joshi¹,

N²

2017

Int J Recent Sci Res

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ARTICLE INFO ABSTRACTThe present investigation was focused on the antioxidant activity of the methanolic extract of Rotula aquatica, a medicinal shrub trailing over gravel in stream beds. The extract exhibited significant (p<0.05) increase in the antioxidant activity with increase in concentration. The extract showed 91.89% DPPH scavenging activity and 74.35% inhibition of nitric oxide at a concentration of 128 μg/mL. Superoxide scavenging activity indicated that 38 μg/mL of extract could inhibit 50% of superoxides. FRAP assay and total reducing potential also signifies the antioxidant potential of the plant extract. The study demonstrated a statistical correlation (r>0.95) between phenol content and antioxidant activity. Overall, the work validates the ethnobotanical usage of the plant and its potential for application in pharmaceutical and food industries.

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“…Our findings concurred with other studies [23,26] that reported that the reducing power of plant extracts from different solvents was concentration-dependent. The reducing ability of plant extracts to transform Fe 2+ to Fe 3+ could be a result of the presence of hydrophilic polyphenolic compounds such as lycopene [27].…”

Section: Free Radical Scavenging Activitiesmentioning

confidence: 99%

A Report on the In Vitro Antioxidant Properties of Vachellia karroo Leaf Extract: A Plant Widely Grazed by Goats in the Central Eastern Cape of South Africa

2017

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Abstract:The polyphenolic constituents and antioxidant activity of aqueous and acetone extracts of Vachellia karroo leaves were determined in order to evaluate its efficacy in scavenging radicals such as DPPH, ferric reducing power and nitric oxide as an antioxidant model. The flavonols and flavonoid and phenolic content of the leaf extracts were also accessed using benchmark phytochemical reaction methods. Results of the phytochemical analyses revealed the presence of flavonoids and flavonol and phenolic compounds in the leaf extracts. The total phenolic content values in the aqueous and acetone leaf extracts were 7.40 and 11.09 mg tannic acid equivalent/g of extract powder, respectively. The total flavonol and flavonoid content values of the aqueous leaf extracts were 9.90 and 53.23 mg quercetin equivalent/g of extract, respectively, while those of the acetone leaf extracts were 1.18 and 5.18 mg quercetin equivalent/g of extract, respectively. At 0.2 mg/mL, the values for the scavenging activities of the acetone and aqueous extracts of the V. karroo leaves were significantly higher (p < 0.05) than that of the ascorbic acid but comparable to BHT against ferric oxide radicals. The findings from the study reveal that the antioxidative potentials of V. karroo leaf extract and could serve as free radical inhibitors, possibly acting as principal antioxidants.

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Chemical composition and antioxidant and radical‐scavenging activities of Periploca laevigata root bark extracts

Cited by 49 publications

References 76 publications

Phytochemical constituents and antioxidant properties of acetone extract of <i>Cleome gynandra</i> (L.) growing in the Eastern Cape, South Africa.

Phytochemical constituents and antioxidant properties of acetone extract of <i>Cleome gynandra</i> (L.) growing in the Eastern Cape, South Africa.

In-vitro assessment of antioxidant potential of rotula aquatic lour extract

A Report on the In Vitro Antioxidant Properties of Vachellia karroo Leaf Extract: A Plant Widely Grazed by Goats in the Central Eastern Cape of South Africa

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