Chemical composition and antioxidant activity of the essential oil ofSchisandra chinensisfruits

Abstract

This study was designed to examine the composition and in vitro antioxidant activity of the essential oil of Schisandra chinensis fruits. Gas chromatography/mass spectrometry was used to determine the composition of the essential oil. Forty components were identified, representing 90.80% of the oil; ylangene (37.72%), β-himachalene (10.46%) and α-bergamotene (8.57%) were the main components. Antioxidant and radical-scavenging properties were evaluated by means of 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay and β-carotene bleaching assay. In the DPPH assay, IC(50) value of the S. chinensis essential oil was determined as 4.17 mg mL(-1). In the β-carotene bleaching assay, the essential oil (1.0 mg mL(-1)) exhibited 25.89% inhibition against linoleic acid oxidation. In both systems, antioxidant capacity of butylated hydroxytoluene was also determined in parallel experiments.

Induction of reactive oxygen species–mediated apoptosis by purified Schisandrae semen essential oil in human leukemia U937 cells through activation of the caspase cascades and nuclear relocation of mitochondrial apoptogenic factors

“…including antioxidant and antimicrobial activities, have been found in the essential oil [33][34][35][36]. Nevertheless, the biological activities and underlying molecular mechanisms of the potential anti-cancer effects of S. semen essential oil (SSeo) remain unclear.…”

Nrf2-Mediated HO-1 Induction Contributes to Antioxidant Capacity of a Schisandrae Fructus Ethanol Extract in C2C12 Myoblasts

“…Schisandrae Fructus is often used to increase physical working capacity and affords stress-protective effects. Schisandrae Fructus and its related compounds possess various biological activities, such as antioxidant, anti-inflammatory, anti-microbial, anti-septic, anti-aging, hepatoprotection, immunostimulating, and anti-cancer effects [ 12 , 13 , 14 , 15 , 16 ]. Although several studies have been conducted on the antioxidant activity of Schisandrae Fructus, the molecular Nrf2/HO-1 signaling pathway by which Schisandrae Fructus exerts antioxidant effects has not been reported.…”

Antioxidant Effects of Schisandra chinensis Fruits and Their Active Constituents

“…S. chinensis fruits contain about 1.5% sugars (polysaccharides and monosaccharides; glucose, fructose, galactose, and arabinose), tannins (hydrolysable, e.g., gallic acid esters, and condensed, e.g., proanthocyanidins and catechol-type tannins), color substances (mainly anthocyanins), and about 3% essential oils, with sesquiterpenes as the dominant compounds [6]. α-Bergamotene, β-chamigrene, β-himachalene, and ylangene are the main components of essential oils (about 75%), whereas oxygenated sesquiterpenes, monoterpenes, and oxygenated monoterpenes comprise the smaller part (about 5%) [6].…”