Chemical composition and antioxidant activity of Strobilanthes crispus leaf extract

Abstract

This study investigated the components present in and the total antioxidant activity of leaves of Strobilanthes crispus (L.) Bremek or Saricocalyx crispus (L.) Bremek (Acanthacea). Proximate analyses and total antioxidant activity using ferric thiocyanate and thiobarbituric acid methods were employed. Minerals content was determined using the atomic absorption spectrophotometer, whereas the water-soluble vitamins were determined by means of the UV-VIS spectrophotometer (vitamin C) and fluorimeter (vitamins B(1) and B(2)). Catechin, tannin, caffeine, and alkaloid contents were also studied. All data were compared to the previously reported results of Yerbamate, green tea, black tea, and Indian tea. The dried leaves contained a high amount of total ash (21.6%) as a result of a high amount of minerals including potassium (51%), calcium (24%), sodium (13%), iron (1%), and phosphorus (1%). High content of water-soluble vitamins (C, B(1), and B(2)) contributed to the high antioxidant activity of the leaves. The leaves also contained a moderate amount of other proximate composition as well as other compounds such as catechins, alkaloids, caffeine, and tannin, contributing further to the total antioxidant activity. Catechins of Strobilanthes crispus leaves showed highest antioxidant activity when compared to Yerbamate and vitamin E. Consumption of the leafy extract daily (5 g/day) as an herbal tea could contribute to the additional nutrients and antioxidants needed in the body to enhance the defense system, especially toward the incidence of degenerative diseases.

Anticancer mechanisms of Strobilanthes crispa Blume hexane extract on liver and breast cancer cell lines

“…Stigmasterol and β-sitosterol extracted from S. crispa have been demonstrated to possess anti-cancer effects on liver, breast, and colon carcinoma (22). Other anti-cancer compounds that may be extracted include alkaloids and tannins (20), which have been documented to exhibit anti-cancer properties (37)(38)(39)(40). In order to identify the compounds responsible for the anti-cancer effects, further studies on the isolation and purification of the bioactive compounds from S. crispa are required.…”

“…This bush-like plant is scattered throughout the regions of Madagascar to Malay Archipelago (18). S. crispa has high mineral and phenolic content, and exhibits high antioxidant activity (19,20). In addition, this plant contains alkaloids, tannins, polyphenols, water-soluble vitamins, caffeine, catechins (19,20) and bioactive compounds, including β-sitosterol, and stigmasterol (21).…”

“…S. crispa has high mineral and phenolic content, and exhibits high antioxidant activity (19,20). In addition, this plant contains alkaloids, tannins, polyphenols, water-soluble vitamins, caffeine, catechins (19,20) and bioactive compounds, including β-sitosterol, and stigmasterol (21). A previous study demonstrated that S. crispa leaves possess anti-diabetic, diuretic and blood pressure lowering properties (17).…”

Optimization of Extraction Condition for Supercritical Carbon Dioxide (SCCO 2) Extraction of Strobhilantes crispus (Pecah Kaca) Leaves by Response Surface Methodology

“…It also has been proven scientifically to possess high antioxidant activity, anti-AIDS, and anticancer properties due to its phytochemical constituent especially mineral contents, antioxidant vitamin as well as catechin [8,9]. It is commonly consumed in the form of herbal tea.…”

Subacute oral toxicity study of ethanolic leaves extracts of Strobilanthes crispus in rats

“…(Details on Page 951) and thiamine), phenolic acids (p-hydroxybenzoic acid, p-coumaric acid, caffeic acid, vanillic acid, gentinic acid, ferulic acid and syryngic acid), caffeine, tannin, alkaloid, and catechin [10,11] . In addition to the chemicals stated above, S. crispus leaves also contained cystoliths of calcium carbonate in which the infusion was mildly alkaline [12] .…”