Chemical composition and antimicrobial and antioxidant activity of Helichrysumitalicum (Roth) G.Don subspecies essential oils

Abstract

The chemical composition and the antimicrobial and antioxidant activity of essential oils from two Helichrysum italicum (Roth) G.Don subspecies grown in Bulgaria were investigated. As a result, 95 compounds with concentrations above 0.05% were detected by GC/MS and 46 of them, mainly mono-and sesquiterpenes, representing 79.81% and 85.51% of the total content of the samples, were identified. The main constituents of the essential oil from Helichrysum italicum subsp. microphyllum (plant origin from Bosnia) were monoterpene α-pinene (20.84%) and sesquiterpene γ-curcumene (16.53%), followed by β-selinene (5.59%), ar-curcumene (4.39%), trans-caryophyllene (4.35%), β-diketone italidione I (4.32%), α-selinene (4.28%), and neryl acetate (3.81%). The sesquiterpene hydrocarbons were the dominant groups of chemical constituents in the essential oil, followed by the oxygenated aliphatic hydrocarbons. The main constituents in the H. italicum essential oil (plant origin from France) were neryl acetate (33.87%), γ-curcumene (8.84%), rosifoliol (5.46%), geranyl propionate (4.98%), αr-curcumene (4.31%), italidione I (3.56%), α-eudesmol (3.19%), and limonene (3.02%). The main class of chemical compounds was the oxygenated monoterpenes, followed by sesquiterpene hydrocarbons. H. italicum essential oil from France showed more pronounced antimicrobial activity against the Gram-positive bacteria Staphylococcus aureus and Bacillus subtilis, and the fungus Aspergillus brasiliensis, as well as stronger antioxidant potential.

Formulation and Evaluation of Helichrysum italicum Essential Oil-Based Topical Formulations for Wound Healing in Diabetic Rats

“…The previous study aimed to compare the chemical composition and antioxidant activity of essential oil originating from Bosnia and France and concluded that the chemical composition was in direct line with the antioxidant activity. French oil was found to be rich in oxygenated monoterpenes, while the oil obtained from Bosnian H. italicum was rich in sesquiterpene hydrocarbons, and consequently essential oil from France exhibited higher antioxidant activity [ 25 ]. A potential explanation for the insufficiently potent in vitro antioxidant activity might lie in the fact that essential oils and their pure compounds are not soluble in polar solvents, and therefore they could not show powerful antioxidant activity [ 26 ].…”

Evaluation of the in vitro antibacterial activity of some essential oils and their blends against Staphylococcus spp. isolated from episodes of sheep mastitis

“…It is important to note that the MBC mode values for all the above mentioned EOs did not follow the same trend as the first group, in some cases deviating by two dilutions in comparison to MIC values. However, the wide variability in antimicrobial activity showed by this second group is reported in several studies (Chao et al 2008;Giovannini et al 2016;Imane et al 2020;Mollova et al 2020). The remaining EOs selected for initial screening test showed mild antibacterial activity against isolated staphylococci.…”

Can 2-Aticyto Complex be an Effective Agent for Recovery of The Symptoms and Enhancing Laboratory Parameters in COVID-19 Patients?

“…has been used, its content was quantified as neryl acetate (31%), γ-curcumene (10.7%), neryl propanoate (5.1%), nonyl acetate (10.5%), carvacrol (9.8%), nonyl propanoate (6.8%); and ar-curcumene (6.4%). [18]. In addition to that in another study, content of Helichrysum sp.…”