Chemical composition and antimicrobial activity of different solvent extracts of Carthamus tinctorius flowers

Alkhafaji, Sura L.; Kashamar, Abbass M.; Alkhafaji, Ibrahim H.

doi:10.5958/0974-360x.2020.01055.0

Cited by 5 publications

(2 citation statements)

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“…Therefore, knowledge of risk factors associated with infections could help to strengthen the efforts towards declining the complications and their recurrence. Standardization of protocol for selection of antibiotic, dosage, and course of treatment are required to reduce morbidity and mortality resulting from pyogenic infections (Alkhafaji Sura et al, 2020).…”

Section: Introduction Introduction Introduction Introductionmentioning

confidence: 99%

Prevalence and antibiogram of aerobic bacterial isolates from pus samples in a tertiary care hospital of north Kerala, India

RAJALAKSHMY,

KUMARI,

AHMED

2024

Not Sci Biol

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Assessment of pathogens diversity and evolving drug-resistant pattern is quite essential in the systematic management of infections. To regulate the pyogenic infection, 1350 (783 males and 567 females) pus samples collected from individuals attending a tertiary care hospital in Northern Kerala. Pathogens isolated from the collected pus samples were identified based on the colony morphology, microscopic examination, and biochemical characteristics. About 84.44% of samples showed significant bacteria. The causative organisms were Staphylococcus aureus (28%), Escherichia coli (13%), Pseudomonas aeruginosa (12%), Klebsiella pneumonia (10%), coagulase negative Staphylococcus sp. (8%), Proteus mirabilis (6%), Streptococcus sp. (2%), Enterococcus faecalis (2%), Acenitobactor baumanii (1%), Citrobactor koseri (2%), Enterococcus faecium (2%), Enterococcus sp. (2%), Morganella morganii (1%), Proteus vulgaris (2%), and other less prominent bacteria (3%). The drug-resistant pattern of pathogens analyses against 29 contemporary antibiotics. Pathogenic Gram-negative bacteria (GNB) were sensitive to amikacin > imipenem > meropenem > tazobactum > gentamycin > chloramphenicol> ciprofloxacin > levofloxacin and resistant to clindamycin, erythromycin, linezolid, oxacillin, penicillin, and vancomycin. Gram-Positive Bacteria (GPB) were susceptible to linezolid > vancomycin > tetracycline > clindamycin > chloramphenicol > gentamycin > ciprofloxacin, and resistant to amikacin, imipenem, meropenem, and tazobactum. Overall, the study concludes that MDR S. aureus was the predominant cause of pyogenic infections, drug resistance pattern of the pathogens in the selected region and raises concerns for the need to analyze signaling mechanism that transforms a susceptible strain into a resistant to develop a suitable treatment strategy.

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Section: Introduction Introduction Introduction Introductionmentioning

confidence: 99%

Prevalence and antibiogram of aerobic bacterial isolates from pus samples in a tertiary care hospital of north Kerala, India

RAJALAKSHMY,

KUMARI,

AHMED

2024

Not Sci Biol

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“…In Chinese traditional medicine, its flowers have been applied to treat cardiovascular and brain disorders [5]. More recently, Alkhafaji et al [6] reported that extracts of its flowers have numerous antioxidant, antimicrobial, anti-inflammatory, antidepressant, and antitumor properties.…”

Section: Introductionmentioning

confidence: 99%

Effects of NaCl on Antioxidant, Antifungal, and Antibacterial Activities in Safflower Essential Oils

Attia

Harrathi

Alamer

et al. 2021

Plants

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The present study aims to evaluate the antioxidant and antimicrobial activity of essential oils (EO) extracted from safflower plants grown in the absence and presence of NaCl, 50 mM. Plants treated with 50 mM of NaCl showed decreases in root, stem, and leaf dry weight. Results of the essential oils showed that roots have a higher EO yield than leaves and stems. Salinity caused a decrease in this yield in roots and leaves but not in stems. The compounds identified in the EO extracted from these organs belong to seven chemical classes of which the dominant class is the sesquiterpene hydrocarbons. The chemotype of C. tinctorius EO is variable depending on the organ and the treatment. The safflower essential oils showed low antioxidant, antiradical, and iron-reducing activities compared to those of the positive control (BHT). In an antifungal activity test, only two strains, Aspergillus niger and Candida albicans, were found to be highly sensitive to these oils as they showed almost total inhibition of their growth. For antibacterial activity, safflower EOs showed significant antimicrobial activity against Bacillus subtilis, Bacillus cereus, and Xanthomonas campestris in both control and NaCl-treated plants: for these three strains, total inhibition of growth was noted at 50,000 ppm of EO in leaves and roots; whereas for stems, total inhibition was noted only for the third strain (Xanthomonas campestris). For other strains, this inhibition was variable and weak. Salt was found to have no effect on the activities of safflower EOs.

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Ethnomedicinal Uses, Phytochemistry, Pharmacology, and Toxicology of Ruellia tuberosa L.: A Review

Sharma,

Kumar,

Singh

et al. 2024

Chemistry & Biodiversity

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Natural Products continue to be the purest source of physiologically active molecules employed in the identification of possible lead compounds in the drug discovery process. Acanthaceae is a big plant family with around 2500 species, found primarily in subtropical and tropical regions, as well as the Mediterranean, Australia, and the United States. Several species of the Acanthaceae family have been used traditionally to treat a variety of diseases, including gastrointestinal and cardiovascular ailments, etc. Ruellia tuberosa commonly known as “Mexican Bluebell” is a perennial herb that originated in Central America and has spread to some countries in the Southern tropics and Southeast Asia. It has been utilized as a traditional Rasayana plant from ancient times. R. tuberosa extracts and phytochemicals showed potent bioactivities, such as anticancer, anti‐inflammatory, wound healing, antifungal, antimicrobial, anti‐diabetic, hypoglycemic, hypolipidemic, gastro‐protective, and anthelminthic activities. Chemical analyses have unveiled a range of bioactive constituents within the plant, including alkaloids, flavonoids, saponins, and phenolic compounds, suggestive of its therapeutic potential. Collectively, this review provides an overview of R. tuberosa, encompassing its traditional uses, ethnomedicinal importance, phytochemistry, pharmacological properties, and toxicity.

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Chemical composition and antimicrobial activity of different solvent extracts of Carthamus tinctorius flowers

Cited by 5 publications

References 0 publications

Prevalence and antibiogram of aerobic bacterial isolates from pus samples in a tertiary care hospital of north Kerala, India

Prevalence and antibiogram of aerobic bacterial isolates from pus samples in a tertiary care hospital of north Kerala, India

Effects of NaCl on Antioxidant, Antifungal, and Antibacterial Activities in Safflower Essential Oils

Ethnomedicinal Uses, Phytochemistry, Pharmacology, and Toxicology of Ruellia tuberosa L.: A Review

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