Chemical Composition and Antimicrobial Activity of Essential Oil from <i>Eupatorium triplinerve </i> Vahl. Aerial Parts

Abstract

Eupatorium triplinerve Vahl belongs to the Asteraceae family, popularly known as Ayapana .It is a perennial shrub native to Amazon rainforests of South America. Its leaves are used through infusions, decoctions, baths, and tea. It is largely used in Brazilian folk medicine as sedative, febrifuge, stimulant, tonic and anti-inflammatory. The essential oil from aerial parts of Eupatorium triplinerve was analysis by gas chromatography mass spectroscopy (GC-MS). Thirty compounds representing 98.24 % of the oil were identified. The major compounds were 2-tert-butyl – 1, 4-methoxybenzene (74.3 %) and b –Selinene (8.6 %). The antibacterial activity of the essential oil was evaluated against ten bacteria (including Gram positive and Gram negative) and six phytopathogenic fungi. The oil exhibited moderated antibacterial and strong antifungal activity against all the test pathogens. The highest zone inhibition was recorded against Salamella typhae (21mm) followed by Shigella sonnei (18mm) at a concentration of 20μl/ disc on the other standard Ampicillin 20mg/ disc showed on average of 14-34mm diameter of zone inhibition against the test organism. The lowest antifungal activities were recorded against Macrophomina phaseoline, and Botryodiplodia theobromae. The highest Alternaria alternate (12000ppm).Further pharmacological and toxicology studies will be required to establish the therapeutic uses of this oil.

A Mini Review: The Application of Eupatorium Plants as Potential Cosmetic Ingredients

“…The present study reveals that different extracts from E. triplinerve leaves contain a diverse range of secondary metabolites and had an antibacterial activity against all of the microorganisms tested. In addition, the E. triplinerve plant can be used to find natural products, which may lead to new pharmaceutical development [27].…”

“…The essential oil from the plant has been found to have various restorative properties, including acting as a central nervous system (CNS) depressant, pain-relieving effects, and narcotic impacts. The ethanolic extract has an antibacterial and antifungal effect, and can be used as a disinfectant or for the treatment of different ulcers and hemorrhages [24,[27][28][29][30]. The conventional utilization of the leaves of E. triplinerve as anthelmintics has been affirmed.…”

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“…There are many plants with ethno-pharmacological background that have been gastro-protective and used in traditional medicine 14,15 . The purpose of this study design is to develop different graded gastric ulceration in experimental model and to search out whether our selected plant Ayapana triplinervis (AT) has protective efficacy even on severe grade ulcers or not 16,17 . Rats were treated with three different doses of indomethacin 10mg, 20mg and 40mg/kg body weight/day for 15 days Table 1 and after sacrifice accordingly to clinical manifestation of gastric environment and different gastric secreting parameters, we have divided these three different doses of indomethacin treated experimental rats in mild, moderate and severe grade ulcerated group.…”