Chemical Composition and Antifungal Activity of Foeniculum vulgare Mill

Abstract

The essential oils of plants have been widely recognized in the pharmaceutical industry due to their various benefits as well as their biological activities. In Algeria, the seeds of Foeniculum vulgare Mill (Family Apiaceae) are widely utilized in herbal medicine. We aimed to examine the chemical composition of seed essential oil of this species, and to reveal its in vitro antifungal activity against Candida albicans, Aspergillus flavus, Aspergillus niger, Rhizopus sp., Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton violaceum, Microsporumgypseum, Microsporumcanis and Rhodotorula sp. Chemical analysis of essential oil isolated by hydro-distillation was carried out by GC-FID and GC-MS. The basic components of the essential oil were estragole (84.8%), limonene (7.8%), fenchone (3.1%) and α-pinene (1.3%). The essential oil of F. vulgare revealed higher antifungal activities particularly against C. albicans and Aspergillus species with MIC values of 0.16-0.2 mg/ml.

Chemical composition and synergistic effect of three Moroccan lavender EOs with ciprofloxacin against foodborne bacteria: a promising approach to modulate antimicrobial resistance

“…bacterial cell membrane(Simsek and Duman 2017;Nafis et al 2020). Several studies showed that EOs characterized by high amounts of fenchone exhibited a high inhibitory capacity on the microbial cell, especially against pathogenic yeasts like Candida species(Garzoli et al 2018;Belabdelli et al 2020) Varsha et al (2015). demonstrated that 2,4-di-tert-butylphenol had a fungicidal potential against Aspergillus niger, Fusarium oxysporum and Penicillium chrysogenum.…”

Mold‐deteriorated archaeological Egyptian papyri: Biodeteriogens, monitoring the deterioration, and treatment approach

“…Alam et al (2019) found that the basic constituents of fennel oil were benzaldehyde‐4‐methoxy (8.01%), fenchone (11.68%), 2‐pentanone (25.01%), and trans ‐anetholes (31.49%). However, Belabdelli et al (2020) reported that the main components of fennel oil were estragole (84.8%), limonene (7.8%), fenchone (3.1%), and α‐pinene (1.3%); they added that the oil had a potent antifungal activity particularly against Aspergillus species. The components of EOs can be utilized for both short‐ and long‐term protection.…”

The Antioxidant and Antimicrobial Potential of Persian Indigenous Herbs as an Alternatives for Nitrate and Nitrite in the Preservation of Meat and Meat Products: An Overview

“…Estragole (10.42%) was identified to be the second most abundant phenylpropanoid in fennel oil, followed by limonene (6.24%), fenchone (5.45%), and other minor components in the EO of fennel seeds [200]. According to another study, estragole (84.8%), limonene (7.8%), fenchone (3.1%), and α-pinene (1.3%) constitute the basic components of the EO derived from seeds of Foeniculum vulgare Mill [201]. Furthermore, 60 compounds representing 90.1-98.7% of the EOs derived from leaves of Florence fennel were identified.…”