Chemical Composition and Antibacterial Activity of Kaempferia galanga Essential Oil

Yang, Yang

doi:10.17957/ijab/15.0560

Cited by 13 publications

(12 citation statements)

References 25 publications

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“…Ethyl p -methoxycinnamate ( 105 ) also isolated from K. galanga rhizomes have been shown based on a resazurin micro-titer assay to inhibit Mycobacterium tuberculosis H37Ra, H37Rv, multidrug-resistant, and drug-susceptible isolates with MIC 0.242–0.485 mM [27]. Its essential oil also displays strong antibacterial activity against Staphylococcus aureus and Salmonella typhimurium , and weak activity against Escherichia coli [28]. Moreover, essential oils extracted from three varieties of K. galanga exhibited potent larvicidal activity [29].…”

Section: Biological Activitymentioning

confidence: 99%

Recent Advances in Kaempferia Phytochemistry and Biological Activity: A Comprehensive Review

et al. 2019

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Background: Plants belonging to the genus Kaempferia (family: Zingiberaceae) are distributed in Asia, especially in the southeast region, and Thailand. They have been widely used in traditional medicines to cure metabolic disorders, inflammation, urinary tract infections, fevers, coughs, hypertension, erectile dysfunction, abdominal and gastrointestinal ailments, asthma, wounds, rheumatism, epilepsy, and skin diseases. Objective: Herein, we reported a comprehensive review, including the traditional applications, biological and pharmacological advances, and phytochemical constituents of Kaempheria species from 1972 up to early 2019. Materials and methods: All the information and reported studies concerning Kaempheria plants were summarized from library and digital databases (e.g., Google Scholar, Sci-finder, PubMed, Springer, Elsevier, MDPI, Web of Science, etc.). The correlation between the Kaempheria species was evaluated via principal component analysis (PCA) and agglomerative hierarchical clustering (AHC), based on the main chemical classes of compounds. Results: Approximately 141 chemical constituents have been isolated and reported from Kaempferia species, such as isopimarane, abietane, labdane and clerodane diterpenoids, flavonoids, phenolic acids, phenyl-heptanoids, curcuminoids, tetrahydropyrano-phenolic, and steroids. A probable biosynthesis pathway for the isopimaradiene skeleton is illustrated. In addition, 15 main documented components of volatile oils of Kaempheria were summarized. Biological activities including anticancer, anti-inflammatory, antimicrobial, anticholinesterase, antioxidant, anti-obesity-induced dermatopathy, wound healing, neuroprotective, anti-allergenic, and anti-nociceptive were demonstrated. Conclusions: Up to date, significant advances in phytochemical and pharmacological studies of different Kaempheria species have been witnessed. So, the traditional uses of these plants have been clarified via modern in vitro and in vivo biological studies. In addition, these traditional uses and reported biological results could be correlated via the chemical characterization of these plants. All these data will support the biologists in the elucidation of the biological mechanisms of these plants.

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Section: Biological Activitymentioning

confidence: 99%

Recent Advances in Kaempferia Phytochemistry and Biological Activity: A Comprehensive Review

et al. 2019

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“…Volatile oils are generally composed of esters, hydrocarbons, terpenes and aromatic compounds. The 19 major compounds of essential oils are esters and terpenoids such as ethyl cinnamate, p-methoxycinnamate, pentadecane, δ-selinene, borneol, eucalyptol ( Fan et al, 2005 ; Zhou et al, 2006 ; Zhang, 2007 ; Cui et al, 2008 ; Wang et al, 2009 ; Sutthanont et al, 2010 ; Liu et al, 2014 ; Luo et al, 2014 ; Raina and Abraham, 2016 ; Yang et al, 2018 ) ( Table 4 ; Figure 2 ).…”

Section: Phytochemistrymentioning

confidence: 99%

“…(KGPs) were extracted and purified for the first time, and further investigated by different spectroscopic techniques such as HPGPC, FTIR, IC. Results showed that fucose (80), arabinose (81), xylose (82), rhamnose (83), mannose (84), galactose (85), glucose (86), glucuronic acid (87), and galacturonic acid (88) were the main components of KGPs, and their the molar ratio is 0.37: 3.12: 1.23: 3.09: 1.00: 6.39: 1.36: 0.91: 1.27, which significantly indicated that KGPs were heterogeneous acidic polysaccharides ( Yang et al, 2018 ).…”

Section: Phytochemistrymentioning

confidence: 99%

Kaempferia galanga L.: Progresses in Phytochemistry, Pharmacology, Toxicology and Ethnomedicinal Uses

Wang

Zhao

et al. 2021

Front. Pharmacol.

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K. galanga is an aromatic medicinal herb. It is locally to India and distributed in China, Myanmar, Indonesia, Malaysia, and Thailand. K. galanga is a Traditional Chinese Herb Medicine (TCHM), which has been applied to treat cold, dry cough, toothaches, rheumatism, hypertension and so on. In addition, it has been used widely as spices since its highly aromas. The aim of this review is to compile and update the current progresses of ethnomedicinal uses, phytochemistry, pharmacology and toxicology of K. galanga. All the data on K. galanga were based on different classical literary works, multiple electronic databases including SciFinder, Web of Science, PubMed, etc. The results showed that ninety-seven compounds have been identified from rhizome of K. galanga, including terpenoids, phenolics, cyclic dipeptides, flavonoids, diarylheptanoids, fatty acids and esters. Modern pharmacology studies revealed that extracts or secondary metabolites of the herb possessed anti-inflammatory, anti-oxidant, anti-tumorous, anti-bacterial, and anti-angiogenesis effects, which were closely related to its abundant ethnomedicinal uses. In conclusion, although previous research works have provided various information of K. galanga, more in-depth studies are still necessary to systemically evaluate phytochemistry, pharmacological activities, toxicity and quality control of this herb.

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“…According to [23], Kencur essential oil showed strong inhibitory activity against Salmonella typhimurium, Staphylococcus aureus and Escherichia coli. Antimicrobial activity can occur due to membrane damage, cell wall damage and damage to electron transport [24].…”

Section: A Activity Of Inhibition Zone Of Hard Candy With Kencur Essential Oilmentioning

confidence: 99%

“…Antimicrobial activity can occur due to membrane damage, cell wall damage and damage to electron transport [24]. The mechanism of changes that occur due to the administration of Kencur essential oil has been reported in study by [23], where the use of essential oils causes structural changes in bacterial cells as well as nucleic acids and causes proteins to undergo lysis, eventually leading to cell damage. Giving Kencur essential oil causes bacterial cells to stick together, cell membranes to undergo lysis and changes in bacterial morphology, including severe damage, defects, holes and wrinkles.…”

Section: A Activity Of Inhibition Zone Of Hard Candy With Kencur Essential Oilmentioning

confidence: 99%

Antibacterial Activity of Kaempferia Galanga L. Hard Candy Against Streptococcus pyogenes and Staphylococcus aureus Bacteria Growth

et al. 2021

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Aromatic ginger (Kaempferia Galanga L.) is a spice plant that has a high volatile content with active compounds of ethyl p-methoxy cinnamate (23.65%) and ethyl cinnamate (5.98%). These two compounds have been reported to have antibacterial activity against Streptococcus pyogenes and Staphylococcus aureus, which are two types of bacteria that can cause sore throat. The application of aromatic ginger essential oil on hard candy can potentially reduce inflammation in the throat. This study aims to determine the effect of aromatic ginger essential oil concentration on hard candy in inhibiting the growth of Streptococcus pyogenes and Staphylococcus aureus bacteria and to determine their acceptance by the panelists. This research was conducted with 6 treatments of variations in the concentration of aromatic ginger essential oil, including 0%, 0.2%, 0.4%, 0.6%, 0.8%, and 1%. The results showed that the higher the concentration of aromatic ginger essential oil on hard candy would further increase the inhibition of the growth of Streptococcus pyogenes and Staphylococcus aureus bacteria. The highest inhibitory activity and the highest panelist acceptance was 1% essential oil concentration with 3.29% moisture content, 0.12% ash content, and 7.13% reducing sugar. The use of aromatic ginger essential oil on hard candy as a flavoring and well as inhibiting the growth of strep throat-causing bacteria (Streptococcus pyogenes and Staphylococcus aureus) has the potential to be developed. Keywords: Antibacterial, hard candy, aromatic ginger, essential oil, Streptococcus pyogenes, Staphylococcus aureus

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Chemical Composition and Antibacterial Activity of Kaempferia galanga Essential Oil

Cited by 13 publications

References 25 publications

Recent Advances in Kaempferia Phytochemistry and Biological Activity: A Comprehensive Review

Recent Advances in Kaempferia Phytochemistry and Biological Activity: A Comprehensive Review

Kaempferia galanga L.: Progresses in Phytochemistry, Pharmacology, Toxicology and Ethnomedicinal Uses

Antibacterial Activity of Kaempferia Galanga L. Hard Candy Against Streptococcus pyogenes and Staphylococcus aureus Bacteria Growth

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