Chemical characterization, antioxidant and cytotoxic activities of Brazilian red propolis

Frozza, Caroline Olivieri da Silva; Garcia, Charlene Silvestrin Celi; Gambato, Gabriela; Souza, Marcia Denize Oliveira de; Salvador, Mirian; Moura, Sidnei; Padilha, Francine Ferreira; Seixas, Fabiana Kömmling; Collares, Tiago; Borsuk, Sibele; Dellagostin, Odir A.; Henriques, João Antônio Pêgas; Roesch‐Ely, Mariana

doi:10.1016/j.fct.2012.11.013

Cited by 178 publications

(106 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Furthermore, total flavonoid content in Brazilian red propolis is correlated with antioxidant activity, suggesting that all the phenolic and flavonoid compounds present contribute to this activity [64]. Chinese red propolis had a higher antioxidant activity than propolis from other sources, which was attributed predominantly to CAPE [65].…”

Section: Antioxidant Activitymentioning

confidence: 99%

Emerging Roles of Propolis: Antioxidant, Cardioprotective, and Antiangiogenic Actions

Daleprane

Abdalla

2013

Evidence-Based Complementary and Alternative Medicine

View full text Add to dashboard Cite

Propolis has attracted attention in recent years due to its beneficial effects, which make it a potential preventive and therapeutic agent as well as a useful additive in food and cosmetics. The aim of this review is to discuss the growing evidence that propolis may, via a diverse array of biological actions, assist in the prevention of some inflammation-mediated pathologies including cardiovascular disease. The active components of propolis that have been identified so far include polyphenols and flavonoids. These compounds have cardioprotective, vasoprotective, antioxidant, antiatherosclerotic, anti-inflammatory and antiangiogenic actions. Many studies have been undertaken to elucidate the mechanism(s) by which propolis acts, which involve cellular signaling targets and interactions at the genomic level. This review will highlight the effects of propolis that may assist in the prevention of chronic degenerative diseases, such as cardiovascular disease.

show abstract

Section: Antioxidant Activitymentioning

confidence: 99%

Emerging Roles of Propolis: Antioxidant, Cardioprotective, and Antiangiogenic Actions

Daleprane

Abdalla

2013

Evidence-Based Complementary and Alternative Medicine

View full text Add to dashboard Cite

show abstract

“…Coupled with various detection techniques, such as a diode array detector (DAD) [1,21,40,47] and/or mass spectrometry, it enables both identiication and quantiication of polyphenols [42,45,46]. Since phenolic components can vary greatly, the suitable technique is liquid chromatography coupled with various types of mass detection, LC-MS enables high selectivity, sensitivity and universality when analyzing various polyphenolic components in their complex matrices.…”

Section: Evaluation Of the Phenolic Contentmentioning

confidence: 99%

“…The determination begins with an extraction step by means of solvents, which are mostly mixtures of water-alcohol in diferent proportions. Aqueous ethanol solutions (25-70 % v/v) are used in some work for 12-24 hours under stirring [42,43]. While the methanolic extraction is used in diferent proportions with water [1,44], there is still work using combined techniques of aqueous extraction, with heating or acidiication, and subsequent ethanol extraction [40,45].…”

Section: Evaluation Of the Phenolic Contentmentioning

confidence: 99%

Honey as a Functional Food

Luchese¹,

Prudêncio²,

Guerra³

2017

Honey Analysis

View full text Add to dashboard Cite

The most well-known functional properties of honey are its antioxidant and antimicrobial activities. The bioactive components of honey are afected by the lora from which it is produced and by geographical variations. Phenolic compounds promote, among other activities, high antioxidant action, being capable of minimizing intracellular oxidative damage associated with cellular aging, apoptosis and neurodegenerative diseases. A living cell system would provide a beter platform for determining antioxidant activity, since the bioactive honey compounds can act modulating antioxidant defense gene expression. Indeed, phenolic compounds, amino acids and reducing sugars are among the substances responsible for honey antioxidant activity. Most of phenolic compounds also exert antimicrobial activity against a number of pathogens and spoilage microorganisms. The antimicrobial activity of honey is also due to the action of enzymes. In addition, honey was found to contain lactic acid bacteria (LAB), which itself produce a myriad of active compounds that remain in variable amounts in mature honey. In addition, these antioxidant compounds might play a key role as prebiotic, protecting and stimulating growth of probiotic bacteria. Oligosaccharides present in honey are well-known prebiotic substances stimulating growth, activity and protecting probiotic bacteria during passage through the gastrointestinal tract and during storage of the products. This chapter describes the main bioactive components of honey, especially with respect to the phenolic compounds and their antioxidant activity and assay methods.

show abstract

“…[9][10][11][12] The characteristic red color of the product is due to pigments called retusapurpurins. 13 Some of the red propolis constituents, such as chalcones, neoflavonoids, isoflavones and pterocarpns, are classes of secondary metabolites characteristic of the subfamily Faboideae of the family Fabaceae (Leguminosae).…”

Section: Brazilian Red Propolismentioning

confidence: 99%

Brazilian Red Propolis: Legitimate Name of the Plant Resin Source

Salatino

2018

MOJFPT

View full text Add to dashboard Cite

Red propolis ranks as the second most produced Brazilian propolis type. Its main chemical constituents are phenolic substances typical of the subfamily Faboideae of the Fabaceae (Leguminosae) family, such as neoflavanoids, chalcones, flavanones and isoflavonoids, among them isoflavones (e.g. biochanin a, daidzein) and pterocarpans (e.g. medicarpin). The plant source of Brazilian red propolis has been referred to as Dalbergia ecastophyllum throughout the propolis literature. Such scientific binomial, however, is a synonym of the legitimate name Dalbergia ecastaphyllum. Citation: Salatino ASMLF. Brazilian red propolis: legitimate name of the plant resin source. Keywords

show abstract

Chemical characterization, antioxidant and cytotoxic activities of Brazilian red propolis

Cited by 178 publications

References 32 publications

Emerging Roles of Propolis: Antioxidant, Cardioprotective, and Antiangiogenic Actions

Emerging Roles of Propolis: Antioxidant, Cardioprotective, and Antiangiogenic Actions

Honey as a Functional Food

Brazilian Red Propolis: Legitimate Name of the Plant Resin Source

Contact Info

Product

Resources

About