Chemical and photochemical degradation of human hair: A free-volume microprobe study

Chandrashekara, M.; Ranganathaiah, C.

doi:10.1016/j.jphotobiol.2010.07.014

Cited by 30 publications

(22 citation statements)

References 40 publications

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“…The fluorescence of this fluorophore was found to change in a predictable manner producing strong characteristic fluorescence when excited with ultraviolet light [7] [8]. This fact generates great interest for utilizing fluorescence spectroscopy to quantify damage from ionizing radiation.…”

Section: Introductionmentioning

confidence: 99%

Changes in Human Hair Induced by UV- and Gamma Irradiation

Palma¹,

González‐Gómez²,

Galicia³

et al. 2016

ABB

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The effect of UV-and 137 Cs gamma radiation on the structural and chemical integrity of human hair was studied to determine the feasibility of using human hair as a non-invasive biomarker of radiation exposure to ionized gamma-and non-ionized UV-radiation. Steady state tryptophan (Trp) fluorescence and chemical analytical methods were used to evaluate the molecular integrity of Trp fluorophores and SH-groups in hair proteins and to assess the radiation induced damage quantitatively. It was found that human hair fibers were progressively damaged by exposure to both UV-and ionized gamma radiation. Damage to the hair was evidenced by a decrease in the fluorescence intensity as a result of observed depletion of the amino acid tryptophan as well as significant reduction in a number of free SH-groups in hair proteins. Hair damage was dose-dependent for exposures between 0 and 10.0 Gy and 0 -20 J/cm 2 of UV-radiation. Additional results demonstrate that hair-fibers exposed to gamma rays, with much higher quantum energy than UV, undergo a smaller extent of changes in Trp fluorescence than when exposed to lower or equal energy of UV-irradiation. The stable Trp fluorophore appears to be extremely sensitive to UVradiation in contrast to the ionized gamma radiation whose damage is originated from the reaction of free radicals and direct deposition of energy. We conclude that fluorescence spectroscopy represents a useful tool in the quantitative evaluation of the radiation exposure and could also be used for the rapid and non-invasive assessment of radiation dose i.e. biodosimeter. The approach is simple, non-invasive and appears to have considerable potential that enables quantitative evaluation of radiation dose exposure in a single hair fiber.

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Section: Introductionmentioning

confidence: 99%

Changes in Human Hair Induced by UV- and Gamma Irradiation

Palma¹,

González‐Gómez²,

Galicia³

et al. 2016

ABB

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show abstract

“…Melanin almost totally dissipates as heat the absorbed UV radiation hence it has an important protective role against photodegradation [12,13].…”

Section: Introductionmentioning

confidence: 99%

Thermal degradation of keratin waste

Brebu¹,

Spiridon²

2011

Journal of Analytical and Applied Pyrolysis

172

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“…314 Positron annihilation provides early detection of coating degradation (after a few days of natural weathering), depth profile information, and information on degradation on molecular level. 317 The photosensitive amino acid residues present in the amorphous domains of virgin/bleached hair crosslinked under ambient conditions. 315 Also combined effect of salt and UV on coating durability has been studied by PALS.…”

Section: Positron Annihilation Lifetime Spectroscopymentioning

confidence: 99%

“…315 The method can be used as a portable tool to monitor degradation on large objects exposed to natural conditions (e.g., paint on cars). 317 The gel fraction and the positron annihilation lifetime are measured to assess the effect of crosslinking. 316 PALS found application in studies of photodegradation of human hair, especially to compare its stability with bleached hair.…”

Section: Positron Annihilation Lifetime Spectroscopymentioning

confidence: 99%

Testing Methods of Weathered Specimen

Wypych¹

2013

Handbook of Material Weathering

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Chemical and photochemical degradation of human hair: A free-volume microprobe study

Cited by 30 publications

References 40 publications

Changes in Human Hair Induced by UV- and Gamma Irradiation

Changes in Human Hair Induced by UV- and Gamma Irradiation

Thermal degradation of keratin waste

Testing Methods of Weathered Specimen

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