Chemical and pharmacological evaluation of different ayurvedic preparations of iron

Pandit, Sudipta; Biswas, Tuhin Kanti; Debnath, P. K.; Saha, Achintya; Chowdhury, Uttam Kumar; Shaw, Barnabas; Sen, S. K.; Mukherjee, Biswajit

doi:10.1016/s0378-8741(99)00003-3

Cited by 46 publications

(27 citation statements)

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“…[26272829303132333435363738] Amalaki , due to Madhura Rasa (sweet taste) and Sheeta Virya (cold potency) reduces Pitta [2627] and thus breaks down the main factor in the pathogenesis of Pandu Roga . Further, it contains richest source of vitamin-C, which helps in the absorption of iron thus increases its bioavailability.…”

Section: Discussionmentioning

confidence: 99%

“…Further, it contains richest source of vitamin-C, which helps in the absorption of iron thus increases its bioavailability. [36] Yasthimadhu , due to Varnya (complexion promoting) and Pitta pacifying property[2829] maintains the normal color of the skin. Guduchi being Tikta Rasa (bitter taste) increases appetite, Krimighna (anti helmentic) and effective against many infections.…”

Section: Discussionmentioning

confidence: 99%

“…[34] Lauha Bhasma also has a significant hematinic and cytoprotective activity,[35] hemoglobin regeneration efficacy. [36]…”

Section: Methodsmentioning

confidence: 99%

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Dhatrilauha : Right choice for iron deficiency anemia in pregnancy

Roy

Dwivedi

2014

AYU

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Background:Anemia in pregnancy is multi-factorial. Iron deficiency anemia (IDA) is the most common one. Major cause is increased demand of iron during pregnancy. In Ayurveda, under Pandu-Roga the features of anemia are described. It is characterized by Vaivarnyata or Varnanasha (change/destruction in normal color of the body), a disorder of Pitta vitiation. Ayurvedic management is an effective way of curing anemia in general by a large number of Lauha preparations of which Dhatrilauha has been used widely for centuries.Aim:To evaluate the effect of Dhatrilauha in the management of IDA based on the scientific parameters among pregnant patients.Materials and Methods:A total of 58 cases were selected by simple randomized sampling method as per inclusion criteria of pregnant women between 4th and 7th months of pregnancy with a clinical diagnosis and laboratory confirmation of IDA. Dhatrilauha 500 mg in two divided doses after food with normal potable water were given for 45 days with three follow-ups, each of 15 days intervals. Final assessment was done after completion of 45 days and results were statistically analyzed by using Cochran's Q-test and Student's t-test.Results:Dhatrilauha showed statistically significant (P < 0.01) improvement in the majority of sign-symptoms and objective parameters such as weakness, fatigue, palpitation, effort intolerance, breathlessness, heartburn, pallor, constipation, hemoglobin, red blood cells (RBC), hematocrit, mean corpuscular volume, mean corpuscular hemoglobin concentration, RBC distribution width, mean platelet volume, serum iron, and total iron binding capacity.Conclusion:Dhatrilauha possesses many fold effectiveness in anemia (IDA), which was evidenced with the significant results obtained in the majority of parameters in this study.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Dhatrilauha : Right choice for iron deficiency anemia in pregnancy

Roy

Dwivedi

2014

AYU

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“…The crude product was powdered and mixed with Aloe vera juice to obtain a homogeneous paste, which was transferred to the earthenware crucibles and sealed with the clay. The calcination was then carried out in the traditional furnace (temperature of 600 • C) following the procedure described by Pandit et al [5]. After overnight calcinations, the product was taken out, the undesired ash was removed and the sample was named as (SNB-1).…”

Section: Methodsmentioning

confidence: 99%

Effect of calcination cycles on the preparation of tin oxide based traditional drug: Studies on its formation and characterization

Wadekar

Rode

Bendale³

et al. 2006

Journal of Pharmaceutical and Biomedical Analysis

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“…The paste was then transferred to an earthen crucible covered with a lid and sealed with sealing clay. Then, it was subjected to calcination following the procedure described by Pandit et al [7].…”

Section: Methodsmentioning

confidence: 99%