Chemical and metabolic characteristics of 1-naphthyl .beta.-D-glucoside

Abstract

Wales who conducted the pathological examination of trout in this study and the Monsanto Chemical Company who provided us with Aroclor 1254. LITERATURE CITED

Bioavailability in rats of bound and conjugated plant carbamate insecticide residues

“…Being bioavailable, it is likely that the water-soluble carbamate metabolites underwent considerable bioalteration after they were administered to the rats. In vivo cleavage of 1-naphthyl glucoside (Dorough et al, 1974) and the glucosides of 4-and 5-hydroxy carbaryl (Dorough, 1976) has been demonstrated experimentally. The toxicological significance of such cleavage is dependent upon the toxic properties of the released exocons and their ability to withstand enzymatic degradation to innocuous products.…”

“…Urine collected from rats treated with the carbofuran and Croneton metabolites was extracted with chloroform, and the polar phase treated with glucosidase and acid as described for the bean plant water solubles. In addition, the polar urinary radiocarbon was subjected to glucuronidase treatment (Dorough et al, 1974). The feces of rats fed unextractable 14C residues were extracted with acetonitrile and the extract separated into an aqueous and organic solvent phase by the addition of chloroform.…”

Development of a monoclonal antibody based enzyme immunoassay method for analysis of maleic hydrazide

“…Light brown crystals (mp 172-175 °C) precipitated from methanol-ether were identified as MH-glucoside tetraacetate based on UV and IR spectra. 4 was prepared by deacetylation of MH-glucoside tetraacetate with methanolic NH3 (Dorough et al, 1974). Deacetylation was quantitative as shown by TLC, and the residue after evaporation at 77 °C in vacuo (mp 184-187 °C) was identified as 4 based on UV and IR: UV (CH3OH) Xmu 303 nm, eM 1912 ±23 (n = 3); IR (KBr, cm"1) vs (3410, 3340, 3240,1595,1070), s (1675,1650,1280, 995), m (1435,1315,1100, 835).…”

An active immunization approach to generate protective catalytic antibodies

“…To avoid the contamination of free α-naphthol, 0.1 ml of 3 % KMnO % was incubated with the blood for 2 min, extracted with chloroform three times and dried in acuo. The concentration of free α-naphthol in the blood was expected to be very low since it is known to be efficiently transformed into αnaphthyl glucoside, α-naphthyl sulphate or another water-soluble substance, all of which are separated from carbaryl by chloroform extraction [27].…”