Chemical and Genetic Diversity of Ligularia hodgsonii in China

Abstract

Ligularia hodgsonii was found to be diverse in China. Furanoeremophilanes were isolated from samples collected in Yunnan Province, while such compounds were absent from samples from Sichuan, Gansu, and Chongqing. DNA sequencing showed that the Yunnan samples were also genetically distinct. γ-Humulene and a new bisabolane sesquiterpene were isolated.

Bisabolane, Oplopane, and Lignan Constituents of Cremanthodium campanulatum Collected in China

“…The roots of sample 3 (2008-12) (dry weight 3.6 g) produced an extract (89.5 mg). From this extract, compounds 1 (1.9 mg), 3 35 (0.7 mg), 5 (3.4 mg), 6 36 (0.4 mg), 7 28 (0.3 mg), 8 37 (1.2 mg), and 10 (1.3 mg) were isolated. Bisangeloyloxy-3β,4β,10,11bisepoxybisabol-7(14)-en-1β-ol (2)…”

Total Synthesis of Highly Oxygenated Bisabolane Sesquiterpene Isolated from Ligularia lankongensis: Relative and Absolute Configurations of the Natural Product

“…Some of us and co-workers isolated oxidized bisabolane compounds from Ligularia lankongensis , and Ligularia. hodgsonii during a study of the diversity of Ligularia species . However, the relative and absolute configurations at C(8) and C(10) of these compounds were not determined because the configuration of the flexible side chain from the NMR data could not be established.…”