Chemical and biological evaluation of essential oil from <i>Saussurea costus</i> (Falc.) Lipsch. from Garhwal Himalaya collected at different harvesting periods

Benedetto, Cristina; D’Auria, Maurizio; Mecca, Marisabel; Prasad, P.; Singh, Pawan; Singh, Sandeep; Sinisgalli, Chiara; Milella, Luigi

doi:10.1080/14786419.2018.1440219

Cited by 22 publications

(9 citation statements)

References 11 publications

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“…The ferric reducing antioxidant power of samples was determined using FRAP assay with some modifications [ 29 ]. Briefly, 25 μ L of appropriately diluted sample (methanol in blank) was added to 225 μ L of FRAP reagent and incubated at 37°C for 40 min in the dark.…”

Section: Methodsmentioning

confidence: 99%

Antioxidant and Antisenescence Effects of Bergamot Juice

Pozzo

Leo

Faraone

et al. 2018

Oxidative Medicine and Cellular Longevity

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Aging is one of the main risk factor for the onset of cardiovascular diseases; one of the possible explanations could be linked to the age-associated overproduction of free radicals. This increase of oxidative stress can be overcome with a high intake of food antioxidants. In this context, a number of studies have been addressed to assess the antiaging potential of natural antioxidant compounds. Recently, it has been shown that the juice of bergamot (Citrus bergamia Risso et Poiteau), a fruit mostly produced in the Ionian coastal areas of Southern Italy (Calabria), is a valuable source of health-promoting constituents with, among other, antioxidant properties. In order to investigate the potential antiaging effects of this Mediterranean natural antioxidant source, bergamot juices of three different cultivars (“fantastico,” “femminello,” and “castagnaro”) were herein characterized by the mean of high-performance liquid chromatography-photodiode array-electrospray ionization-tandem mass spectrometry. Then, juices were investigated for the evaluation of total polyphenolic and flavonoid contents, cell-free model antioxidant activities, and in vitro antiaging properties on two different cellular models of induced myocardial senescence. The best performing juice was also assessed in vivo. The phytochemical profiles confirmed that juices were rich in flavonoids, both flavone and flavanone glycosides. In addition, two limonoid glycosides were also identified in all cultivars. Each cultivar showed different phenolic and flavonoid contents. In tube results showed the juice robust antioxidant activities that correlate with their phenolic and flavonoid contents. Moreover, for the first time, the ability of juice to counteract the chemical-induced senescence was here demonstrated in both cellular models. Lastly, the in vivo data obtained from mouse hearts evidenced an increase in transcription of genes involved in antiaging and antioxidant responses. The overall results suggest that bergamot juice exerts antioxidant and antisenescence effects, making it useful for nutraceutical purposes.

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Section: Methodsmentioning

confidence: 99%

Antioxidant and Antisenescence Effects of Bergamot Juice

Pozzo

Leo

Faraone

et al. 2018

Oxidative Medicine and Cellular Longevity

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“…Different phytochemical investigations on the chemical composition of the S. costus root EO have revealed a large variability in the relative amounts and composition of the constituents, with recoveries ranging from 0.02 to 3% [ 272 , 273 ]. Besides different eco- and chemotypes, different growing localities, and environmental factors (temperature, relative humidity, irradiance, photoperiod) as well as storage duration may be responsible for this great variance [ 273 , 274 , 275 , 276 ].…”

Section: Essential Oils From Selected Rootsmentioning

confidence: 99%

“…Thus, it has been convincingly illustrated that, biodiversity, harvesting period (month and year), and plant age also have a strong impact on the chemical composition of costus root oil. Moreover, variations in the observed moderate radical scavending and reducing power activities of costus oil have been observed according to the harvesting period, being the highest in samples collected during summer [ 272 ].…”

Section: Essential Oils From Selected Rootsmentioning

confidence: 99%

Back to the Roots—An Overview of the Chemical Composition and Bioactivity of Selected Root-Essential Oils

Lunz

Stappen

2021

Molecules

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Since ancient times, plant roots have been widely used in traditional medicine for treating various ailments and diseases due to their beneficial effects. A large number of studies have demonstrated that—besides their aromatic properties—their biological activity can often be attributed to volatile constituents. This review provides a comprehensive overview of investigations into the chemical composition of essential oils and volatile components obtained from selected aromatic roots, including Angelica archangelica, Armoracia rusticana, Carlina sp., Chrysopogon zizanioides, Coleus forskohlii, Inula helenium, Sassafras albidum, Saussurea costus, and Valeriana officinalis. Additionally, their most important associated biological impacts are reported, such as anticarcinogenic, antimicrobial, antioxidant, pesticidal, and other miscellaneous properties. Various literature and electronic databases—including PubMed, ScienceDirect, Springer, Scopus, Google Scholar, and Wiley—were screened and data was obtained accordingly. The results indicate the promising properties of root-essential oils and their potential as a source for natural biologically active products for flavor, pharmaceutical, agricultural, and fragrance industries. However, more research is required to further establish the mechanism of action mediating these bioactivities as well as essential oil standardization because the chemical composition often strongly varies depending on external factors.

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“…The paste is applied to the inflamed area to relieve pain. The chemical constituents are terpenoids, steroids, phenylpropanoids, lignans, flavonoids and so on (Benedetto et al 2019;Rohit et al 2020). According to the Chinese pharmacopeia (National Pharmacopeia Commission 2020), Radix Aucklandiae for medicinal use should contain at least 15% total costunolide (C 15 H 20 O 2 ) and dehydrocostus lactone (C 5 H 18 O 2 ).…”

mentioning

confidence: 99%

“…The chemical constituents are terpenoids, steroids, phenylpropanoids, lignans, flavonoids and so on (Benedetto et al. 2019 ; Rohit et al. 2020 ).…”

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confidence: 99%

The complete mitochondrial genome of Aucklandia lappa Decne. (Asteraceae, Aucklandia Falc.)

Song

Zhang

Tang

et al. 2021

Mitochondrial DNA Part B

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The complete mitochondrial genome of Aucklandia lappa was sequenced for the first time. The mitochondrial genome length was 320,439 bp, with 45.05% GC contents. There were 67 genes annotated, including 31 known protein-coding genes, 25 tRNAs, and six rRNAs. The maximum likelihood method was used to establish the phylogenetic tree of 37 species. Results have shown that A. lappa and Arctium lappa were sister groups. It reveals the genetic relationship between different species and provides a theoretical basis for the establishment of a classification system.

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Chemical and biological evaluation of essential oil from Saussurea costus (Falc.) Lipsch. from Garhwal Himalaya collected at different harvesting periods

Cited by 22 publications

References 11 publications

Antioxidant and Antisenescence Effects of Bergamot Juice

Antioxidant and Antisenescence Effects of Bergamot Juice

Back to the Roots—An Overview of the Chemical Composition and Bioactivity of Selected Root-Essential Oils

The complete mitochondrial genome of Aucklandia lappa Decne. (Asteraceae, Aucklandia Falc.)

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