Chemical and biological evaluation of essential oils with economic value from Lauraceae species

Abstract

Este trabalho compara pela primeira vez a composição química do óleo essencial das folhas de Licaria canella coletadas em duas estações climáticas. Os resultados foram comparados com os obtidos para o óleo essencial das folhas de outra espécie da família Lauraceae, Aniba canelilla, coletada no mesmo período. Ambos os óleos essenciais foram analisados por CG-DIC e CG-EM, e os resultados indicaram uma grande quantidade de benzenóides, sendo o principal constituinte em L. canella o benzoato de benzila e para A. canelilla, o 1-nitro-2-feniletano. A comparação das atividades biológicas mostrou que o óleo de L. canella (IC 50 19 µg mL-1) foi mais ativo contra as cepas de Leishmania amazonensis e menos citotóxico em cultura de macrófagos do que o de A. canelilla (IC 50 40 µg mL-1). Por outro lado, o óleo de L. canella exibiu uma maior citotoxicidade contra Artemia salina com uma concentração letal (CL 50) igual a 5,25 µg mL-1. This work compares the chemical composition of the essential oils from the leaves of Licaria canella collected in two different seasons. The results of this investigation were compared with the leaf essential oils of other species of the Lauraceae family, Aniba canelilla, collected at the same time. Both essential oils were analyzed by GC-FID and GC-MS. The results demonstrated a larger predominance of benzenoids, being the main constituent benzyl benzoate for L. canella and 1-nitro-2-phenylethane for A. canelilla. The comparison of the biological activities showed that L. canella (IC 50 19 µg mL-1) was more active against Leishmania amazonensis strains and less cytotoxic in macrophage cultures than A. canelilla (IC 50 40 µg mL-1). On the other hand, the L. canella oil displayed a higher cytotoxicity against Artemia salina with a lethal concentration (LC 50), equal to 5.25 µg mL-1 .

CHEMICAL COMPOSITION OF WOOD ESSENTIAL OIL OF Aniba cinnamomiflora C. K. Allen FROM VENEZUELAN ANDES

“…For example, benzyl benzoate (1.3%) is also present in A. riparia (R. Luz et al, 2002) and A. hostamanniana (De Lima et al, 2015) essential oils. This compound is considered a characteristic feature of the genus Aniba (Gottlieb & Kubitzki, 1981), and is commercially used as a topical medication against several parasitoses (Silva et al, 2009). Although a minor component of this species (0.9%), the monoterpene linalool, usually present in high proportion in rosewood A. rosaeodora (Moreira et al, 2010;Almeida et al, 2013), has anti-inflammatory, antioxidant, and inhibitory activities, as well as bactericidal effects (Peana et al, 2002;Liu, et al, 2012).…”

Distribution of alkaloids in woody plants

“…Finally, the Lauraceae family includes several species able to produce isoquinoline alkaloids (33,34). The most frequently detected alkaloids in Lauraceae barks include reticuline, boldine, aporphine, corydine, cinnamolaurine, laurotetatnine and laurolitsine (33,35,36).…”

Biomass production and essential oil yield from leaves, fine stems and resprouts using pruning the crown of Aniba canelilla (H.B.K.) (Lauraceae) in the Central Amazon

“…The 1-nitro-2-phenyletane compound from A. canelilla essential oil did not show any difference among seasons (Silva et al 2009) but another study found that the concentration was higher during the wet season (Taveira et al 2003). As in the essential oil chemical composition, the essential oil yield between plant organs also has different responses.…”

“…These factors can be the cause on variation in the seasonality (Duarte et al 2009), although some studies did not find any differences between seasons (Rajeswara Rao et al 1996;Lopes et al 1997;Silva et al 2009). One experiment with A. canelilla seedlings showed that moisture deficiency and light irradiance decreases essential oil yield in roots and leaves respectively (Atroch 2008).…”